KEGG ORTHOLOGY: K23115

ORTHOLOGY: K23115

Entry

K23115                      KO

Symbol

TTI2

Name

TELO2-interacting protein 2

Disease

H00768

Autosomal recessive intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K23115  TTI2; TELO2-interacting protein 2
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Check point factors
   Triple T complex
    K23115  TTI2; TELO2-interacting protein 2

Genes

HSA:	80185(TTI2)

PTR:	747397(TTI2)

PPS:	100971552(TTI2)

GGO:	101133678(TTI2)

PON:	100444974(TTI2)

NLE:	100591215(TTI2)

HMH:	116461700(TTI2)

MCC:	696776(TTI2)

MCF:	102118643(TTI2)

MTHB:

126961777

MNI:	105476612(TTI2)

CSAB:

103215600(TTI2)

CATY:

105579264(TTI2)

PANU:

101018818(TTI2)

TGE:	112630325(TTI2)

MLEU:

105536881(TTI2)

RRO:	104669248(TTI2)

RBB:	108518771(TTI2)

TFN:	117094654(TTI2)

PTEH:

111544144(TTI2)

CANG:

105525191(TTI2)

CJC:	100408575(TTI2)

SBQ:	101050810(TTI2)

CIMI:

108309692(TTI2)

CSYR:

103265302(TTI2)

MMUR:

105877331(TTI2)

LCAT:

123626479(TTI2)

PCOQ:

105813805(TTI2)

OGA:	100941379(TTI2)

MMU:	234138(Tti2)

MCAL:

110300362(Tti2)

MPAH:

110336565(Tti2)

RNO:	290811(Tti2)

MCOC:

116069112(Tti2)

ANU:	117721571(Tti2)

MUN:	110549821(Tti2)

CGE:	100760553(Tti2)

MAUA:

101828155(Tti2)

PROB:

127220396(Tti2)

PLEU:

114698505(Tti2)

MORG:

121462359(Tti2)

MFOT:

126504468

AAMP:

119811991(Tti2)

NGI:	103743575(Tti2)

HGL:	101719521(Tti2)

CPOC:

100721725(Tti2)

CCAN:

109685008(Tti2)

DORD:

105991535

DSP:	122125937(Tti2)

PLOP:

125339397(Tti2)

NCAR:

124983272

MMMA:

107155372(Tti2)

OCU:

100358152

OPI:	101523067(TTI2)

TUP:	102476425(TTI2)

GVR:	103608072(TTI2)

CFA:	608405(TTI2)

CLUD:

112645329(TTI2)

VVP:	112916112(TTI2)

VLG:	121489503(TTI2)

NPO:	129516034(TTI2)

AML:	100479638(TTI2)

UMR:	103681353(TTI2)

UAH:	113262145(TTI2)

UAR:	123780375(TTI2)

ELK:

111144441

LLV:

125092599

MPUF:

101683685(TTI2)

MNP:	132006508(TTI2)

MLK:	131820651(TTI2)

NVS:	122889897(TTI2)

ORO:	101376565(TTI2)

EJU:	114203356 114203360

ZCA:	113925104(TTI2)

MLX:	118009982(TTI2)

NSU:	110584061(TTI2)

LWW:	102727159(TTI2)

FCA:	101097888(TTI2)

PYU:	121039815(TTI2)

PCOO:

112870017(TTI2)

PBG:	122471951(TTI2)

PVIV:

125164046(TTI2)

LRUF:

124520578

PTG:	102960679(TTI2)

PPAD:

109277293(TTI2)

PUC:

125923374

AJU:

106966542

HHV:	120246811(TTI2)

BTA:	535350(TTI2)

BOM:	102274369(TTI2)

BIU:	109553448(TTI2)

BBUB:

102412155(TTI2)

BBIS:

104987739(TTI2)

CHX:	102183662(TTI2)

OAS:	101108629(TTI2)

BTAX:

128068191(TTI2)

ODA:	120865635(TTI2)

CCAD:

122432381(TTI2)

MBEZ:

129549385(TTI2)

SSC:	100526252(TTI2)

CFR:	102511294(TTI2)

CBAI:

105067615(TTI2)

CDK:	105095808(TTI2)

VPC:	102535716(TTI2)

BACU:

103013214(TTI2)

BMUS:

118887800(TTI2)

LVE:	103080003(TTI2)

OOR:	101275404(TTI2)

DLE:	111173490(TTI2)

PCAD:

102982173(TTI2)

PSIU:

116746877(TTI2)

NASI:

112413170(TTI2)

ECB:	100061066(TTI2)

EPZ:	103555765(TTI2)

EAI:	106835393(TTI2)

MYB:	102261752(TTI2)

MYD:	102767685(TTI2)

MMYO:

118649925(TTI2)

MLF:	102439504(TTI2)

PKL:	118728315(TTI2)

EFUS:

103290339(TTI2)

MNA:	107535351(TTI2)

DRO:	112306781(TTI2)

SHON:

118993152(TTI2)

AJM:	119036878(TTI2)

PDIC:

114508860(TTI2)

PHAS:

123807603(TTI2)

MMF:	118622780(TTI2)

PPAM:

129064829(TTI2)

RFQ:	117021548(TTI2)

PALE:

102884339(TTI2)

PGIG:

120595709(TTI2)

PVP:	105300894(TTI2) 105310262

RAY:	107503199(TTI2)

MJV:	108394023(TTI2)

TOD:	119257796(TTI2)

SARA:

101550145(TTI2)

SETR:

126006832(TTI2)

LAV:	100675665(TTI2)

TMU:

101346248

ETF:	101639349(TTI2)

DNM:	101437544(TTI2)

MDO:	100032879(TTI2)

GAS:	123234874(TTI2)

SHR:	100933875(TTI2)

AFZ:

127548211

PCW:	110207600(TTI2)

GGA:	426923(TTI2)

PCOC:

116234550(TTI2)

MGP:	100545039(TTI2)

CJO:	107323767(TTI2)

TPAI:

128089949(TTI2)

LMUT:

125685254(TTI2)

NMEL:

110387136(TTI2)

APLA:

101789418(TTI2)

ACYG:

106044387(TTI2)

CATA:

118256119(TTI2)

AFUL:

116499332(TTI2)

TGU:	100228535(TTI2)

LSR:	110477345(TTI2)

SCAN:

103824519(TTI2)

PMOA:

120505195(TTI2)

OTC:	121346704(TTI2)

PRUF:

121355873(TTI2)

GFR:	102037411(TTI2)

FAB:	101814116(TTI2)

OMA:	130262038(TTI2)

PHI:	102112770(TTI2)

PMAJ:

107213831(TTI2)

CCAE:

111938834(TTI2)

CCW:	104694892(TTI2)

CBRC:

103615203(TTI2)

ETL:	114064385(TTI2)

ACHL:

103812024(TTI2)

SVG:	106863068(TTI2)

MMEA:

130586444(TTI2)

HRT:	120748289(TTI2)

FPG:	101917564(TTI2)

FCH:	102048886(TTI2)

CLV:	102090137(TTI2)

EGZ:	104127839(TTI2)

NNI:	104016046(TTI2)

PCRI:

104026614(TTI2)

PLET:

104628773(TTI2)

EHS:	104505385(TTI2)

PCAO:

104040781(TTI2)

ACUN:

113488100(TTI2)

TALA:

104359962(TTI2)

PADL:

103912379(TTI2)

AFOR:

103904697(TTI2)

ACHC:

115350054(TTI2)

HALD:

104325721(TTI2)

HLE:	104828821(TTI2)

AGEN:

126051424

GCL:

127025258

CCRI:

104156976(TTI2)

CSTI:

104558548(TTI2)

CMAC:

104475375(TTI2)

MUI:	104535708(TTI2)

BREG:

104631624(TTI2)

FGA:	104075360(TTI2)

GSTE:

104261817(TTI2)

LDI:	104351706(TTI2)

OHA:	104332166(TTI2)

NNT:	104402603(TTI2)

SHAB:

115618362(TTI2)

DPUB:

104306063(TTI2)

PGUU:

104460568(TTI2)

ACAR:

104520071(TTI2)

CPEA:

104384862(TTI2)

AVIT:

104272392(TTI2)

CVF:	104285863(TTI2)

RTD:	128919580(TTI2)

CUCA:

104068562(TTI2)

TEO:	104376937(TTI2)

BRHI:

104496026(TTI2)

AAM:	106498828(TTI2)

AROW:

112973610(TTI2)

NPD:	112949977(TTI2)

DNE:	112996686(TTI2)

SCAM:

104145916(TTI2)

ASN:	102370626(TTI2)

AMJ:	102576762(TTI2)

CPOO:

109317442(TTI2)

GGN:	109295573(TTI2)

PSS:	102461670(TTI2)

CMY:	102933974(TTI2)

CCAY:

125626359(TTI2)

DCC:	119848703(TTI2)

CPIC:

101931067(TTI2)

TST:	117872995(TTI2)

CABI:

116839835(TTI2)

MRV:	120398955(TTI2)

ASAO:

132782523(TTI2)

PVT:	110089338(TTI2)

SUND:

121934971(TTI2)

PBI:	103062224(TTI2)

PMUR:

107291993(TTI2)

CTIG:

120313927(TTI2)

TSR:	106540248(TTI2)

PGUT:

117677030(TTI2)

APRI:

131203803(TTI2)

PTEX:

113447682(TTI2)

NSS:	113414457(TTI2)

VKO:	123027111(TTI2)

PMUA:

114585379(TTI2)

PRAF:

128402529(TTI2)

ZVI:	118097103(TTI2)

HCG:	128333942(TTI2)

GJA:	107115375(TTI2)

STOW:

125441620(TTI2)

EMC:	129342396(TTI2)

XLA:	108711603(tti2.L)

XTR:	100487242(tti2)

NPR:	108795036(TTI2)

RTEM:

120933119(TTI2)

BBUF:

120986337(TTI2)

BGAR:

122927143(TTI2)

MUO:	115469381(TTI2)

GSH:	117362844(TTI2)

DRE:	100334230(tti2)

SRX:

SANH:

SGH:

CCAR:

CAUA:

113070687(tti2)

CGIB:

128018330

PTET:

122350588(tti2)

LROH:

127169342(tti2)

OMC:	131545458(tti2)

PPRM:

120474857(tti2)

RKG:	130081987(tti2)

MAMB:

125279520(tti2)

CIDE:

127517604

MASI:

127424543

TROS:

130568539(tti2)

TDW:	130407176(tti2)

MANU:

129413554(tti2)

IPU:

108265876

IFU:	128607406(tti2)

PHYP:

113546026(tti2)

SMEO:

124400487(tti2)

TFD:	113643104(tti2)

TVC:	132853726(tti2)

AMEX:

103047080(tti2)

CMAO:

118813102(tti2)

EEE:	113590248(tti2)

CHAR:

105907583(tti2)

TRU:	101066065(tti2)

TFS:	130525876(tti2)

TNG:	GSTEN00010763G001

NCC:	104951785(tti2)

TBEN:

117472808(tti2)

CGOB:

115012940(tti2)

PGEO:

117452454(tti2)

GACU:

117535008(tti2)

EMAC:

134872954(tti2)

ELY:	117252940(tti2)

EFO:	125890879(tti2)

SLUC:

116056733(tti2)

ECRA:

117944858(tti2)

ESP:	116689935(tti2)

PFLV:

114555681(tti2)

GAT:

120831201

PPUG:

119225424(tti2)

AFB:	129101566(tti2)

CLUM:

117736030(tti2)

PSWI:

130196506(tti2)

MSAM:

119891563(tti2)

SCHU:

122876774(tti2)

CUD:	121509623(tti2)

ALAT:

119019946(tti2)

MZE:	101478663(tti2)

ONL:	102076186(tti2)

OAU:	116328429(tti2)

OLA:	101157224(tti2)

OML:	112136364(tti2)

CSAI:

133451195(tti2)

XMA:	102224046(tti2)

XCO:	114144374(tti2)

XHE:	116730365(tti2)

PRET:

103470753 103470756

PFOR:

103129632(tti2)

PLAI:

106962998(tti2)

PMEI:

106904241(tti2)

GAF:	122828591(tti2)

PPRL:

129366236(tti2)

CVG:	107097917(tti2)

CTUL:

119791350(tti2)

GMU:	124877982(tti2)

NFU:	107386160(tti2)

KMR:	108241571(tti2)

ALIM:

106527824(tti2)

NWH:	119413110(tti2)

AOCE:

111583633(tti2)

MCEP:

125012007(tti2)

CSEM:

103397987(tti2)

POV:	109645376(tti2)

SSEN:

122770062(tti2)

HHIP:

117768389(tti2)

HSP:	118114706(tti2)

SMAU:

118313732(tti2)

LCF:

108875434

SDU:	111236944(tti2)

SLAL:

111645990(tti2)

XGL:	120805840(tti2)

HCQ:	109525297(tti2)

SSCV:

125993800

SBIA:

133498982(tti2)

PEE:	133399626(tti2)

PTAO:

133475667(tti2)

BPEC:

110172509(tti2)

MALB:

109957315(tti2)

BSPL:

114862920(tti2)

SJO:	128364787(tti2)

SASA:

106587029(tti2)

STRU:

115167656(tti2)

OTW:	112248929(tti2)

OMY:	110526121(tti2)

OGO:	124033979(tti2)

ONE:	115112000(tti2)

OKI:	109884397(tti2)

OKE:	118393604(tti2)

SALP:

111974072(tti2)

SNH:	120045024(tti2)

CCLU:

121584605(tti2)

ELS:	105014048(tti2)

SFM:	108940320(tti2)

PKI:	111857519(tti2)

AANG:

118206436(tti2)

LOC:	102695899(tti2)

PSPA:

121302468 121303128

ARUT:

117397859 117397921

PSEX:

120539309(tti2)

LCM:	102348457(TTI2)

CMK:	103187828(tti2)

RTP:	109938118(tti2)

CPLA:

122543096(tti2)

HOC:	132837023(tti2)

LERI:

129713159(tti2)

PMRN:

116946696(TTI2)

LRJ:	133353001(TTI2)

BBEL:

CIN:

SPU:

LPIC:

APLC:

AJC:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208920

BANY:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

API:

DNX:

AGS:

RMD:

DVT:

CLEC:

HHAL:

NLU:

MQU:

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_325742

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

CQD:

PTRU:

MNZ:

HAZT:

EAF:

LSM:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

PTEP:

ABRU:

SDM:

HRO:	HELRODRAFT_158818

LGI:	LOTGIDRAFT_54709

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CVN:

CANU:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

OSN:

LAK:

SMM:	Smp_137130

OVI:	T265_01791

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

TAD:	TRIADDRAFT_55162

AQU:

ATH:

ALY:

CRB:

CSAT:

104782452 104785433 104792832

EUS:	EUTSA_v10016686mg

BRP:

103857891

BNA:	106394097 106420743(BNAC03G22300D) 106438062

BOE:

106334896

RSZ:	108847298 130509058

THJ:

104810050

CPAP:

110819251

CIT:

102619829

CIC:	CICLE_v10031701mg

PVY:

MINC:

TCC:

GRA:

GHI:	107900451 107962041

GAB:

108486183

HSYR:

120119482 120151818 120196168 120204000

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_001G239600g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj0g3v0253809.1(Lj0g3v0253809.1)

ADU:

107469638

AIP:

107622628

AHF:	112715437 112785097

LANG:

109330104

PCIN:

129294273

QSA:	O6P43_013911

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:	112011754 112025563

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107775524 107779240

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

121775569 121777401 121792014

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130792938 130793172

BVG:	104883411 104903721

SOE:

110805674

CQI:	110699226 110733396

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os06t0694100-01(Os06g0694100)

OBR:

102722023

OGL:

127775766

BDI:

100843113

ATS:	109768676 109772885

TDC:	119329350 119338385 119340462

TAES:

123148758 123159152 123161327 123166631

LPER:

127312383

LRD:	124661968 124665960

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	121983707 122038281

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_413376 SELMODRAFT_423529

PPP:

112288948

OLU:	OSTLU_17567

OTA:	OT_ostta12g01330

MIS:	MICPUN_54343

MPP:	MICPUCDRAFT_63299(JGI:MicpuC2_63299)

MBR:	MONBRDRAFT_26411

SRE:	PTSG_03060

PIF:	PITG_11191

PSOJ:

PHYSODRAFT_311376

SPAR:

SPRG_05558 SPRG_18347

» show all

Reference

PMID:20810650

Authors

Hurov KE, Cotta-Ramusino C, Elledge SJ

Title

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

Journal

Genes Dev 24:1939-50 (2010)
DOI:10.1101/gad.1934210

Sequence

[hsa:80185]

LinkDB

DBGET integrated database retrieval system