KEGG   ORTHOLOGY: K23122
Entry
K23122                      KO                                     
Symbol
cntM
Name
staphylopine/pseudopaline/yersinopine synthase [EC:1.5.1.52 1.5.1.-]
Pathway
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Module
M00949  Staphylopine biosynthesis, L-histidine => staphylopine
Reaction
R12237  staphylopine:NADP+ oxidoreductase [(2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate]-forming
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K23122  cntM; staphylopine/pseudopaline/yersinopine synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.52  staphylopine dehydrogenase
     K23122  cntM; staphylopine/pseudopaline/yersinopine synthase
Other DBs
COG: COG4408
Genes
YPE: YPO1347
YPK: y2835
YPH: YPC_2840
YPA: YPA_0633
YPN: YPN_2637
YPM: YP_1249
YPP: YPDSF_2352
YPG: YpAngola_A1577
YPZ: YPZ3_1229
YPT: A1122_18850
YPD: YPD4_1192
YPX: YPD8_0953
YPW: CH59_495
YPJ: CH55_1201
YPV: BZ15_2207
YPL: CH46_3782
YPS: YPTB1373
YPO: BZ17_1146
YPI: YpsIP31758_2631
YPY: YPK_2716
YPB: YPTS_1472
YPQ: DJ40_855
YPU: BZ21_649
YPR: BZ20_606
YPC: BZ23_983
YPF: BZ19_781
YSI: BF17_15915
SMW: SMWW4_v1c21330
SERF: L085_18090
SERS: SERRSCBI_09990
SSUR: ATE40_007150
SURI: J0X03_13350
SNEM: NLX84_10750
SNEV: OI978_22605
SERB: QEP77_11955
SERH: GF111_01775
ANS: ArsFIN_50680
VNI: VIBNI_B0489
VAQ: FIV01_17875
PAE: PA4835
PAEV: N297_5004
PAEI: N296_5004
PAU: PA14_63920
PAG: PLES_52201
PAF: PAM18_4946
PNC: NCGM2_0694
PAEB: NCGM1900_5573
PDK: PADK2_25660
PSG: G655_25505
PRP: M062_25520
PAEP: PA1S_26280
PAER: PA1R_gp2756
PAEM: U769_26535
PAEL: T223_26730
PAES: SCV20265_5493
PAEU: BN889_05384
PAEG: AI22_07720
PAEC: M802_5002
PAEO: M801_4869
SECH: B18_11690
PAP: PSPA7_5554
PPAA: B7D75_25160
SDO: SD1155_03775
BSON: S101395_03011
BHA: BH2073
LSP: Bsph_1831
LFU: HR49_11880
LYB: C3943_14845
LYC: FH508_0007345
LYO: NV349_06630
MEKU: HUW50_21730
MDG: K8L98_19845
MSEE: WCV65_15735
MHRF: QLQ22_19990
SLMS: MM221_10315
FPN: ABE65_005810
FAR: ABE41_005935
AND: GRQ40_16000
SAU: SA2256
SAV: SAV2468
SAW: SAHV_2452
SAH: SaurJH1_2544
SAJ: SaurJH9_2495
SAM: MW2392
SAS: SAS2359
SAR: SAR2555
SAC: SACOL2477
SAX: USA300HOU_2459
SAA: SAUSA300_2412
SAO: SAOUHSC_02768
SAE: NWMN_2365
SAD: SAAV_2534
SUU: M013TW_2428(cntM)
SUV: SAVC_11210
SUE: SAOV_2518c
SUJ: SAA6159_02365(cntM)
SUK: SAA6008_02509
SUC: ECTR2_2325
SUT: SAT0131_02667
SUQ: HMPREF0772_10721
SUZ: MS7_2481
SUD: ST398NM01_2518
SUX: SAEMRSA15_23660
SUW: SATW20_25960
SUG: SAPIG2518
SUF: SARLGA251_22480
SAUA: SAAG_00294
SAUE: RSAU_002306
SAUN: SAKOR_02452
SAUS: SA40_2216
SAUU: SA957_2300
SAUG: SA268_2373
SAUZ: SAZ172_2571
SAUT: SAI1T1_2018380
SAUJ: SAI2T2_1018390
SAUK: SAI3T3_1018380
SAUQ: SAI4T8_1018390
SAUV: SAI7S6_1018380
SAUW: SAI5S5_1018320
SAUX: SAI6T6_1018320
SAUY: SAI8T7_1018360
SAUF: X998_2452
SAB: SAB2351c
SUY: SA2981_2405
SAUB: C248_2518
SAUM: BN843_25080
SAUC: CA347_2547
SAUR: SABB_01209
SAUI: AZ30_12960
SAUD: CH52_06645
SAMS: NI36_12270
SUH: SAMSHR1132_22930
SER: SERP2373
SEP: SE_0203
SEPP: SEB_00131
SEPS: DP17_1261
SSD: SPSINT_0078
SDT: SPSE_2399
SDP: NCTC12225_02594
SWA: A284_00420
SPAS: STP1_1304
SXY: BE24_11755
SXL: SXYLSMQ121_0069
SXO: SXYL_00070
SHU: SHYC_11645
SSCH: LH95_11150
SSCZ: RN70_11900
SAGQ: EP23_10520
SLZ: B5P37_06435
SFQ: C7J90_03775
SCAR: DWB96_00450(cntM)
SCHR: DWB92_11720
SSH: NCTC13712_02420
SLLO: ISP08_00450(cntM)
SRAI: LN051_10975
SPSD: JMB28_00745(cntM)
SEDA: MNY58_00465
SROT: ML435_11875(cntM)
SFF: FOB90_08240(cntM)
SSTE: SAMEA4384403_1090
BBE: BBR47_28220
BFM: BP422_09285
BAGR: BA6348_01045
BPAB: PSE45_01835
BREH: HP435_01970
BREP: M655_026370
GYM: GYMC10_2837
PMS: KNP414_01895
PMQ: PM3016_2180
PMW: B2K_11205
PAEA: R70723_16830
PNP: IJ22_25010
PVO: PVOR_17329
PLW: D5F53_15600
PCHI: PC41400_19300 PC41400_19390
PPRT: ET464_05565 ET464_05570
PBAC: HUB98_11420
PTRI: KDC22_17095
PALO: E6C60_2222
PUI: PUW25_11740
PAMY: P9222_12200
PNK: AASFL403_06950
PPAB: KET34_28285
PEZZ: HW560_11455
PELG: ACJ7K1_03520
PAJN: JNUCC32_11020
PAYG: LDO05_10370
PTUN: V6W81_14900 V6W81_23410
PRUD: CIC07_03960
PTAC: ACJYJG_25665
PACU: B9D94_13540
PANA: BBH88_13385
CARG: RSJ17_16755
CLOO: RCG18_20495
HHW: NCTC503_01796
CFM: BJL90_00600
GPD: GII33_20950
ARTQ: CGQ24_13610
AAI: AARI_10900
GAR: AOZ07_05775
GLU: F0M17_05435
GNC: QQS42_05450
PAEY: KUF55_05520
PSDS: K1T35_28800
APRE: CNX65_19680
AMI: Amir_3918
UME: RM788_04610
PLK: CIK06_26265
FNT: HMPREF0405_01276
FNE: FSDG_01139
FVA: FV113G1_15600
FUL: C4N20_14590
FMO: C4N19_08465
 » show all
Reference
PMID:27230378
  Authors
Ghssein G, Brutesco C, Ouerdane L, Fojcik C, Izaute A, Wang S, Hajjar C, Lobinski R, Lemaire D, Richaud P, Voulhoux R, Espaillat A, Cava F, Pignol D, Borezee-Durant E, Arnoux P
  Title
Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus.
  Journal
Science 352:1105-9 (2016)
DOI:10.1126/science.aaf1018
  Sequence
[sav:SAV2468]
Reference
PMID:29091735
  Authors
McFarlane JS, Lamb AL
  Title
Biosynthesis of an Opine Metallophore by Pseudomonas aeruginosa.
  Journal
Biochemistry 56:5967-5971 (2017)
DOI:10.1021/acs.biochem.7b00804
  Sequence
[pae:PA4835]
Reference
PMID:29618515
  Authors
McFarlane JS, Davis CL, Lamb AL
  Title
Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase.
  Journal
J Biol Chem 293:8009-8019 (2018)
DOI:10.1074/jbc.RA118.002007
  Sequence
[ypk:y2835]
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