KEGG ORTHOLOGY: K23214

ORTHOLOGY: K23214

Entry

K23214                      KO

Symbol

AUTS2

Name

autism susceptibility gene 2 protein

Pathway

map03083

Polycomb repressive complex

Disease

H00773

Autosomal dominant intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    K23214  AUTS2; autism susceptibility gene 2 protein
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K23214  AUTS2; autism susceptibility gene 2 protein
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.3/1.5)
     K23214  AUTS2; autism susceptibility gene 2 protein

Genes

HSA:	26053(AUTS2)

PTR:	463457(AUTS2)

PPS:	100990974(AUTS2)

PON:	100447576(AUTS2)

PPYG:

129040496(AUTS2)

NLE:	100606262(AUTS2)

HMH:	116812026(AUTS2)

SSYN:

129489804(AUTS2)

MCC:	701038(AUTS2)

MCF:	102129166(AUTS2)

MTHB:

126950292

MNI:	105466343(AUTS2)

CSAB:

103246605(AUTS2)

CATY:

105593330(AUTS2)

PANU:

101026402(AUTS2)

TGE:	112620345(AUTS2)

MLEU:

105548722(AUTS2)

RRO:	104672938(AUTS2)

RBB:	108544185(AUTS2)

TFN:	117072857(AUTS2)

PTEH:

111547033(AUTS2)

CANG:

105504751(AUTS2)

CJC:	100392628(AUTS2) 100402891

SBQ:	101053134(AUTS2)

CIMI:

108314445(AUTS2)

ANAN:

105714928(AUTS2)

CSYR:

103264513(AUTS2)

MMUR:

105871160(AUTS2)

LCAT:

123632645(AUTS2)

PCOQ:

105807085(AUTS2)

OGA:	100949036(AUTS2)

MMU:	319974(Auts2)

MCAL:

110294627(Auts2)

MPAH:

110313162(Auts2)

RNO:	304419(Auts2)

MCOC:

116070612(Auts2)

ANU:	117698286(Auts2)

ASYL:

127673080(Auts2)

MUN:	110560854(Auts2)

CGE:	100750545(Auts2)

MAUA:

101842010(Auts2)

PROB:

127236873(Auts2)

PLEU:

114693696(Auts2)

MORG:

121446045(Auts2)

MFOT:

126516018

AAMP:

119825405(Auts2)

NGI:	103748478(Auts2)

HGL:	101717933(Auts2)

CPOC:

100735074(Auts2)

CCAN:

109683138(Auts2)

DORD:

105998463(Auts2)

DSP:	122114888(Auts2)

PLOP:

125368531(Auts2)

NCAR:

124970816

MMMA:

107146579(Auts2)

ITI:

101974270

OCU:

100351572

OPI:	101525432(AUTS2)

TUP:	102471722(AUTS2)

GVR:	103593378(AUTS2)

CFA:	479709(AUTS2)

CLUD:

112646103(AUTS2)

VVP:	112934096(AUTS2)

VLG:	121487448(AUTS2)

NPO:	129519516(AUTS2)

AML:	100479098(AUTS2)

UMR:	103670236(AUTS2)

UAH:	113267983(AUTS2)

UAR:	123784716(AUTS2)

ELK:

111145610

LLV:

125091127

MPUF:

101690874(AUTS2)

MNP:	132026649(AUTS2)

MLK:	131819580(AUTS2)

NVS:	122895336(AUTS2)

ORO:	101371175 101379151(AUTS2)

EJU:	114214342(AUTS2) 114214403

ZCA:	113931844(AUTS2) 113932100

MLX:	117999516(AUTS2)

NSU:	110589958(AUTS2)

FCA:	101099855(AUTS2)

PYU:	121017827(AUTS2)

PCOO:

112859879(AUTS2)

PBG:	122472039(AUTS2)

PVIV:

125154304(AUTS2)

LRUF:

124519380

LGF:	123589404(AUTS2)

AJU:

106972847

PTG:	102968057(AUTS2)

PPAD:

109250499(AUTS2)

PUC:	125917571 125917579

PLEZ:

122209341(AUTS2)

HHV:	120235654(AUTS2)

BTA:	615936(AUTS2)

BOM:	102277741(AUTS2)

BIU:

109578163

BBUB:

102414450(AUTS2)

BBIS:

104998944(AUTS2)

CHX:	102175180(AUTS2)

OAS:	114110670(AUTS2)

BTAX:

128062213(AUTS2)

CSUM:

138076075(AUTS2)

ODA:	120878086(AUTS2)

CCAD:

122433079(AUTS2)

MREE:

136160737(AUTS2)

OVR:	110122328(AUTS2)

MBEZ:

129545596(AUTS2)

SSC:	100515476(AUTS2)

CFR:	102512792(AUTS2)

CBAI:

105082866(AUTS2)

CDK:	105089733(AUTS2)

VPC:	102543194(AUTS2)

BACU:

103012147(AUTS2)

BMUS:

118880530(AUTS2)

OOR:	101276084(AUTS2)

LALB:

132505054(AUTS2)

DLE:	111182068(AUTS2)

PCAD:

102977671(AUTS2)

PSIU:

116739760(AUTS2)

NASI:

112412446(AUTS2)

ECB:	100062562(AUTS2)

EPZ:	103553797(AUTS2)

EAI:	106835459(AUTS2)

MYB:	102244643(AUTS2)

MYD:	102755121(AUTS2)

MMYO:

118656682(AUTS2)

MLF:	102428461(AUTS2)

MDT:	132233165(AUTS2)

MYUM:

139008985(AUTS2)

PKL:	118703883(AUTS2)

EFUS:

103286054(AUTS2)

MNA:	107546693(AUTS2)

DRO:	112314832(AUTS2)

SHON:

118984021(AUTS2)

AJM:	119042023(AUTS2)

PDIC:

114491650(AUTS2)

PHAS:

123806325(AUTS2)

MMF:	118642474(AUTS2)

PPAM:

129083754(AUTS2)

HAI:	109389147(AUTS2)

RFQ:	117025321(AUTS2)

PALE:

102885110(AUTS2)

PGIG:

120591695(AUTS2)

PVP:	105296716(AUTS2)

RAY:	107515693(AUTS2)

MJV:	108401742(AUTS2)

TOD:	119241493(AUTS2)

SARA:

101550877(AUTS2)

SFUM:

130045018(AUTS2)

SETR:

126029918

LAV:	100672170(AUTS2)

TMU:

101344138

ETF:	101655548(AUTS2)

DNM:	101439859(AUTS2)

MDO:	100011864(AUTS2)

GAS:	123246828(AUTS2)

SHR:	100918813(AUTS2)

AFZ:

127558734

PCW:	110222095(AUTS2)

TVP:	118858306(AUTS2)

PBRV:

138162398(AUTS2)

OAA:	100076981(AUTS2)

TACU:

119939098(AUTS2)

GGA:	417481(AUTS2)

PCOC:

116228203(AUTS2)

MGP:	100551021(AUTS2)

CJO:	107322672(AUTS2)

TPAI:

128083348(AUTS2)

LMUT:

125703069(AUTS2)

NMEL:

110407919(AUTS2)

APLA:

101803047(AUTS2)

ACYG:

106041047(AUTS2)

CATA:

118254216(AUTS2)

AFUL:

116497152(AUTS2)

TGU:	116809141(AUTS2)

LSR:	110472023(AUTS2)

SCAN:

103823610(AUTS2)

PMOA:

120513462(AUTS2)

OTC:	121346891(AUTS2)

PRUF:

121362979(AUTS2)

ATRC:

139600213(AUTS2)

GFR:	102036146(AUTS2)

FAB:	101822142(AUTS2)

OMA:	130260947(AUTS2)

PHI:	102100070(AUTS2)

PMAJ:

107212675(AUTS2)

CCAE:

111937921(AUTS2)

CCW:	104695796(AUTS2)

CBRC:

103616350(AUTS2)

ACOE:

138120733(AUTS2)

ETL:	114068239(AUTS2)

ZAB:	102066386(AUTS2)

ZLE:	135455959(AUTS2)

ACHL:

103797717(AUTS2)

SVG:	106856253(AUTS2)

MMEA:

130580252(AUTS2)

HRT:	120761246(AUTS2)

SATI:

136369978(AUTS2)

CCIC:

134052547(AUTS2)

FPG:	101914451(AUTS2)

FCH:	102056384(AUTS2)

CCRI:

104164394(AUTS2)

NNT:	104413176(AUTS2)

SHAB:

115601957(AUTS2)

ACUN:

113487351(AUTS2)

TALA:

104362300(AUTS2)

ACHC:

115347012(AUTS2)

HALD:

104321917(AUTS2)

HLE:	104843143(AUTS2)

AGEN:

126039942

HHAR:

128148950(AUTS2)

GCL:

127024297

CSTI:

104550120(AUTS2)

LDI:	104343427(AUTS2)

MNB:	103772564(AUTS2)

DPUB:

104300242(AUTS2)

PPUS:

135187687(AUTS2)

AVIT:

104267717(AUTS2)

BRHI:

104492110(AUTS2)

EGZ:	104131771(AUTS2)

NNI:	104012448(AUTS2)

PCRI:

104030131(AUTS2)

PCAO:

104045501(AUTS2)

PADL:

103912870(AUTS2)

AFOR:

103896536(AUTS2)

FGA:	104069155(AUTS2)

CBOY:

140660957(AUTS2)

CLV:	102090894(AUTS2)

MUI:	104538096(AUTS2)

PGUU:

104470038(AUTS2)

PLET:

104623728(AUTS2)

EHS:	104505904(AUTS2)

CMAC:

104480350(AUTS2)

CUCA:

104064678(AUTS2)

TEO:	104381463(AUTS2)

BREG:

104638619(AUTS2)

OHA:	104339139(AUTS2)

ACAR:

104532589(AUTS2)

CPEA:

104390066(AUTS2)

CVF:	104289852(AUTS2)

RTD:	128913193(AUTS2)

CRID:

134518415(AUTS2)

AAM:	106491715(AUTS2)

AROW:

112964988(AUTS2)

TGT:	104577625(AUTS2)

DNE:	112987402(AUTS2)

SCAM:

104146256(AUTS2)

ASN:	102376740(AUTS2)

AMJ:	102571472(AUTS2)

CPOO:

109316932(AUTS2)

GGN:	109293455(AUTS2)

PSS:	102462070(AUTS2)

CMY:	102938821(AUTS2)

CCAY:

125623853(AUTS2)

DCC:	119844665(AUTS2)

CPIC:

101938508(AUTS2)

TST:	117867563(AUTS2)

CABI:

116831166(AUTS2)

MRV:	120387273(AUTS2)

ACS:	100566460(auts2)

ASAO:

132763463(AUTS2)

PVT:	110083280(AUTS2)

SUND:

121916965

PBI:	103052998(AUTS2)

PMUR:

107300299(AUTS2)

CTIG:

120307347(AUTS2)

TSR:	106538948(AUTS2) 106539154

PGUT:

117667459(AUTS2)

APRI:

131188770(AUTS2)

PTEX:

113441437(AUTS2)

NSS:	113415114(AUTS2)

VKO:	123023607(AUTS2)

PMUA:

114585249(AUTS2)

PRAF:

128402921(AUTS2)

ZVI:	118096926(AUTS2)

HCG:	128336036 128336082

GJA:	107116487(AUTS2)

STOW:

125445724(AUTS2)

EMC:

129345063

XLA:	108708344 108708936

XTR:	100498056(auts2)

NPR:	108788148(AUTS2)

RTEM:

120926624(AUTS2)

BBUF:

120995550(AUTS2)

BGAR:

122932410(AUTS2)

PWL:	138286547(AUTS2) 138304394(FBRS)

MUO:	115456876(AUTS2) 115473884(FBRS)

GSH:	117348765(AUTS2) 117360711(FBRS)

DRE:	100150849(auts2b) 368890(auts2a)

SRX:	107707850 107718788 107720532 107726097 107729123 107747043

SANH:

107657550 107662780 107693947 107701171

SGH:	107548872(auts2) 107555116 107586267 107597539

CCAR:

109078194(auts2b) 109088006 109097628 109097953(auts2a)

CAUA:

113054345 113058389 113076123 113109810 113115147

CGIB:

127966381 127972920 128021147 128029523

PTET:

122353001(auts2a) 122359089(auts2b)

LROH:

127171510(auts2a) 127177308(auts2b)

OMC:	131547839(auts2a) 131554354(auts2b)

PPRM:

120482212(auts2a) 120485666(auts2b)

RKG:	130082783(auts2a)

MAMB:

125248798(auts2b) 125261042(auts2a)

CIDE:

127495273 127520726

CERY:

137005090(auts2b) 137028722(auts2a)

MASI:

127422652 127430323 127432504 127433724

TROS:

130545845(auts2a) 130565106(auts2b)

TDW:	130411735(auts2a) 130428899(auts2b)

MANU:

129437918(auts2b) 129446902(auts2a)

PDAB:

135740251(auts2a) 135771192(auts2b)

IPU:	108278168(auts2b)

IFU:	128621134(auts2b)

PHYP:

113532752(auts2) 113535556

SMEO:

124394560(auts2b)

TFD:	113660439(auts2b)

TVC:	132857750(auts2b)

CGAR:

128533110(auts2b)

NGRA:

132901406(auts2b)

TRN:	134334616(auts2b)

AMEX:

103040710(auts2b)

CMAO:

118800063(auts2b) 118800839(auts2a)

EEE:	113582998(auts2) 113584371

CHAR:

105909135(auts2a)

SPIL:

134080662(auts2a)

TRU:	101067208(auts2)

TFS:	130537222(auts2a)

TNG:	GSTEN00007570G001

LCO:	104924138(auts2)

NCC:	104942550(auts2) 104945269

TBEN:

117469624(auts2a)

CGOB:

115018742(auts2)

PGEO:

117458880(auts2a)

GACU:

117538432(auts2a)

EMAC:

134871691(auts2a)

ELY:	117262354(auts2a)

EFO:	125898827(auts2a)

PLEP:

121952724(auts2a)

SLUC:

116058129(auts2a)

ECRA:

117955949(auts2a)

ESP:	116700506(auts2)

PFLV:

114566410(auts2)

GAT:	120822076(auts2a)

PPUG:

119215028(auts2a)

AFB:	129113359(auts2a)

CLUM:

117742611(auts2a)

PSWI:

130210417(auts2a)

CANA:

137802473(auts2a)

CVE:	137880068(auts2a)

MSAM:

119895575(auts2a)

SCHU:

122888186(auts2a)

CUD:	121518720(auts2a)

SPUL:

138597166(auts2a)

LMIX:

132988478(auts2a)

ALAT:

119030718(auts2a)

ASTR:

137605799(auts2a)

MZE:	101464344(auts2)

ONL:

100698981

OAU:	116320587(auts2a)

OLA:	101174450(auts2)

OML:	112143019(auts2a)

CSAI:

133459848(auts2a)

XMA:	102222906(auts2)

XCO:	114153500(auts2)

XHE:	116728059(auts2)

PRET:

103476108(auts2)

PFOR:

103142101(auts2)

PLAI:

106946456(auts2)

PMEI:

106915848(auts2)

GAF:	122845172(auts2a)

PPRL:

129368786(auts2a)

CVG:	107089937 107093964(auts2)

CTUL:

119796290

GMU:	124876091(auts2a)

NFU:

107386297

KMR:	108244712(auts2a)

ALIM:

106530310(auts2)

NWH:

119420706

AOCE:

111576793(auts2a)

EJA:	138196712(auts2a)

BFRE:

138633726(auts2a)

MCEP:

125020783(auts2a)

CSEM:

103395206(auts2)

POV:	109628684(auts2)

SSEN:

122779404(auts2a)

SSOE:

131458105(auts2a)

HHIP:

117773946(auts2a)

HSP:	118122061(auts2a)

PPLT:

128457562(auts2a)

SMAU:

118301080(auts2a)

LCF:	108893399(auts2a)

SDU:	111222194(auts2)

SLAL:

111663507(auts2)

XGL:	120802719(auts2a)

HCQ:	109531145(auts2)

SSCV:

125982631(auts2a)

SBIA:

133491497(auts2a)

PEE:	133415712(auts2a)

PTAO:

133467018(auts2a)

BPEC:

110165043

ENY:	140361086(auts2a)

MALB:

109967064

BSPL:

114868965(auts2a)

SJO:	128371144(auts2a)

SSCO:

133993744(auts2a)

GMH:	115547311(auts2)

SASA:

106567958 106603524

STRU:

115148879 115154336 115206829

OTW:	112233389 112257841 112267148

OMY:	110533651 110537471

OGO:	123998797 124006347 124010501

ONE:	115105548 115135902 115141875

OKI:	109873450 109891806 109909195

OKE:	118357822 118390087 118391161

OMM:	135545296 135548580 135550687

OCLA:

139382722 139418262 139423096

SALP:

111950415 111980328

SNH:	120045197 120057069

CCLU:

121568008 121573566 121579768

ELS:	105011009(auts2) 105022439

OEP:	134039376(auts2a)

SFM:	108936221(auts2)

PKI:	111854733(auts2)

AANG:

118235691(auts2a)

AROT:

135263868(auts2a)

CCOG:

133108317 133132659(auts2a)

LOC:	102697583(auts2)

PSPA:

121305114(auts2a)

ARUT:

117429727 117430738 117964285

PSEX:

120531520(auts2a)

LCM:	102359242(FBRS) 102360613(AUTS2)

RTP:	109917551(auts2a)

CPLA:

122564081(auts2a)

HOC:	132808894 132830342(auts2a)

LERI:

129710468(auts2a)

LRJ:

BFO:

BBEL:

SPU:

LPIC:

APLC:

AFIL:

AJC:

SKO:

PFLL:

LGI:	LOTGIDRAFT_163411

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MMER:

RPHI:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

Reference

PMID:12160723

Authors

Sultana R, Yu CE, Yu J, Munson J, Chen D, Hua W, Estes A, Cortes F, de la Barra F, Yu D, Haider ST, Trask BJ, Green ED, Raskind WH, Disteche CM, Wijsman E, Dawson G, Storm DR, Schellenberg GD, Villacres EC

Title

Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins.

Journal

Genomics 80:129-34 (2002)
DOI:10.1006/geno.2002.6810

Sequence

[hsa:26053]

LinkDB

DBGET integrated database retrieval system