KEGG ORTHOLOGY: K23965

ORTHOLOGY: K23965

Entry

K23965                      KO

Symbol

RSPH3

Name

radial spoke head protein 3

Disease

H00564

Primary ciliary dyskinesia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K23965  RSPH3; radial spoke head protein 3
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Radial spoke
   K23965  RSPH3; radial spoke head protein 3

Genes

HSA:	83861(RSPH3)

PTR:	463103(RSPH3)

PPS:	100986929(RSPH3)

GGO:	101138352(RSPH3)

PON:	100460624(RSPH3)

PPYG:

129038279(RSPH3)

NLE:	100582630(RSPH3)

HMH:	116473522(RSPH3)

SSYN:

129476045(RSPH3)

MCC:	114669855(RSPH3) 704059

MCF:	102127619(RSPH3)

MTHB:

126953658

MNI:	105492031(RSPH3)

CSAB:

103240811(RSPH3)

CATY:

105581333(RSPH3)

PANU:

100137452(RSPH3)

TGE:	112622842(RSPH3)

MLEU:

105536544(RSPH3)

RRO:	104676649(RSPH3)

RBB:	108540558(RSPH3)

TFN:	117097216(RSPH3)

PTEH:

111538578(RSPH3)

CANG:

105519432(RSPH3)

CJC:	100387715(RSPH3)

SBQ:	101051418(RSPH3)

CIMI:

108311044(RSPH3)

ANAN:

105717701(RSPH3)

CSYR:

103251375(RSPH3)

MMUR:

105868623(RSPH3)

LCAT:

123633421(RSPH3)

PCOQ:

105812386(RSPH3)

OGA:	100941577(RSPH3)

MMU:	100037282(Rsph3b) 66832(Rsph3a)

MCAL:

110284225(Rsph3)

MPAH:

110338227(Rsph3)

RNO:	361476(Rsph3)

MCOC:

116077268(Rsph3)

ANU:	117700177(Rsph3)

ASYL:

127673914(Rsph3)

MUN:	110547893(Rsph3)

CGE:	100762246(Rsph3)

MAUA:

101837838(Rsph3)

PROB:

127237687(Rsph3)

PLEU:

114685673(Rsph3)

MORG:

121466429(Rsph3)

MFOT:

126497678

AAMP:

119821504(Rsph3)

NGI:	103739286(Rsph3)

HGL:	101720107(Rsph3)

CPOC:

100717457(Rsph3)

CCAN:

109700996(Rsph3)

DORD:

105991809(Rsph3)

DSP:	122116124(Rsph3)

PLOP:

125357605(Rsph3)

NCAR:

124989765

MMMA:

107153129(Rsph3)

ITI:	101955468(Rsph3)

OCU:

100356049

OPI:	101536288(RSPH3) 118757858

TUP:	102500738(RSPH3)

GVR:	103585784(RSPH3)

CFA:	484057(RSPH3)

CLUD:

112643463(RSPH3)

VVP:	112935147(RSPH3)

VLG:	121477941(RSPH3)

NPO:	129499800(RSPH3)

AML:	100483988(RSPH3)

UMR:	103660903(RSPH3)

UAH:	113259337(RSPH3)

UAR:	123797408(RSPH3)

ELK:

111158667

LLV:

125101696

MPUF:

101691298(RSPH3)

MNP:	132018735(RSPH3)

MLK:	131833323(RSPH3)

NVS:	122889091(RSPH3)

ORO:	101384980(RSPH3)

EJU:	114209190(RSPH3)

ZCA:	113926932(RSPH3)

MLX:	118001848 118001971

NSU:	110583171(RSPH3)

LWW:	102747062(RSPH3)

FCA:	101096480(RSPH3)

PYU:	121013493(RSPH3)

PCOO:

112862230(RSPH3)

PBG:	122490556(RSPH3)

PVIV:

125166518(RSPH3)

LRUF:

124529371

LGF:	123609968(RSPH3)

AJU:

106982675

PTG:	102949779(RSPH3)

PPAD:

109245465(RSPH3)

PUC:

125939164

PLEZ:

122220550(RSPH3)

HHV:	120245155(RSPH3)

BTA:	533135(RSPH3)

BOM:	102275726(RSPH3)

BIU:

109566709

BBUB:

102407298(RSPH3)

BBIS:

104989281(RSPH3)

CHX:	102170320(RSPH3)

OAS:	101110682(RSPH3)

BTAX:

128053458(RSPH3)

CSUM:

138089594(RSPH3)

ODA:	120862680(RSPH3)

CCAD:

122434128(RSPH3)

MREE:

136163296(RSPH3)

OVR:	110126595(RSPH3)

MBEZ:

129560908(RSPH3)

SSC:	100156750(RSPH3)

CFR:	102510982(RSPH3)

CBAI:

105077458(RSPH3)

CDK:	105103127(RSPH3)

VPC:	102526476(RSPH3)

BACU:

103004440(RSPH3)

BMUS:

118905440(RSPH3)

LVE:	103071858(RSPH3)

OOR:	101286821(RSPH3)

LALB:

132530290(RSPH3)

DLE:	111167514(RSPH3)

PCAD:

102994652(RSPH3)

PSIU:

116763724(RSPH3)

NASI:

112401563(RSPH3)

ECB:	100059353(RSPH3)

EPZ:	103554094(RSPH3)

EAI:	106842032(RSPH3)

MYD:	102772460(RSPH3)

MMYO:

118660515(RSPH3)

MLF:	102423730(RSPH3)

MDT:	132236736(RSPH3)

MYUM:

139012997(RSPH3)

PKL:	118705864(RSPH3)

EFUS:

103297957(RSPH3)

MNA:	107541876(RSPH3)

DRO:	112297290(RSPH3)

SHON:

118988367(RSPH3)

AJM:	119034985(RSPH3)

PDIC:

114495340(RSPH3)

PHAS:

123821756(RSPH3)

MMF:	118620796(RSPH3)

PPAM:

129066953(RSPH3)

HAI:	109393999(RSPH3)

RFQ:	117015659(RSPH3)

PALE:

102898018(RSPH3)

PGIG:

120611433(RSPH3)

PVP:	105303000(RSPH3)

MJV:	108392598(RSPH3)

TOD:	119251552(RSPH3)

SARA:

101538414(RSPH3)

SFUM:

130034684(RSPH3)

SETR:

125995736(RSPH3)

LAV:	100662610(RSPH3)

TMU:

101342452

ETF:	101643701(RSPH3)

DNM:	101411916(RSPH3)

MDO:	100032381(RSPH3)

GAS:	123246961(RSPH3)

SHR:	100921702(RSPH3)

AFZ:

127562365

PCW:	110208598(RSPH3)

TVP:	118833031 118857017(RSPH3)

PBRV:

138147777(RSPH3)

OAA:	100083497(RSPH3)

TACU:

119919543(RSPH3)

GGA:	421663(RSPH3)

PCOC:

116240847(RSPH3)

MGP:	100547101(RSPH3)

CJO:	107311649(RSPH3)

TPAI:

128078880(RSPH3)

LMUT:

125689711(RSPH3)

NMEL:

110396629(RSPH3)

APLA:

101791303(RSPH3)

ACYG:

106044270(RSPH3)

CATA:

118243911(RSPH3)

AFUL:

116488105(RSPH3)

TGU:	100228966(RSPH3)

LSR:	110475912(RSPH3)

SCAN:

103820627(RSPH3)

PMOA:

120501246(RSPH3)

OTC:	121346225(RSPH3)

PRUF:

121354891(RSPH3)

ATRC:

139593527(RSPH3)

GFR:	102036524(RSPH3)

FAB:	101809902(RSPH3)

OMA:	130251695(RSPH3)

PHI:	102103844(RSPH3)

PMAJ:

107201188(RSPH3)

CCAE:

111926758(RSPH3)

CCW:	104693850(RSPH3)

CBRC:

103617686(RSPH3)

ACOE:

138107264(RSPH3)

ETL:	114068471(RSPH3)

ZAB:	102074359(RSPH3)

ZLE:	135444882(RSPH3)

ACHL:

103798793(RSPH3)

SVG:	106860666(RSPH3)

MMEA:

130572854(RSPH3)

HRT:	120750561(RSPH3)

SATI:

136358437(RSPH3)

CCIC:

134041861(RSPH3)

FPG:	101912833(RSPH3)

FCH:	102047892(RSPH3)

CCRI:

104163661(RSPH3)

NNT:

104400194

SHAB:

115613940(RSPH3)

ACUN:

113477865(RSPH3)

TALA:

116959171(RSPH3)

ACHC:

115345043(RSPH3)

HALD:

104311071(RSPH3)

AGEN:

126038812

HHAR:

128140574(RSPH3)

GCL:

127014907

CSTI:

104556855(RSPH3)

LDI:	104350075(RSPH3)

MNB:	103771538(RSPH3)

DPUB:

104301051(RSPH3)

PPUS:

135189232(RSPH3)

AVIT:

104268411(RSPH3)

BRHI:

104501263(RSPH3)

EGZ:	104131122(RSPH3)

NNI:	104008873(RSPH3)

PCAO:

104046258(RSPH3)

PADL:

103912763(RSPH3)

AFOR:

103900789(RSPH3)

FGA:	104071166(RSPH3)

GSTE:

104254366(RSPH3)

CBOY:

140650057(RSPH3)

CLV:	102091812(RSPH3)

MUI:	104540659(RSPH3)

PGUU:

104459023(RSPH3)

PLET:

104615044(RSPH3)

CMAC:

104474254(RSPH3)

CUCA:

104061472(RSPH3)

TEO:	104375682(RSPH3)

BREG:

104629077(RSPH3)

OHA:	104330836(RSPH3)

ACAR:

104525991(RSPH3)

CPEA:

104389547(RSPH3)

CVF:	104284065(RSPH3)

RTD:	128907372(RSPH3)

CRID:

134513175(RSPH3)

AAM:	106497927(RSPH3)

AROW:

112974890(RSPH3)

NPD:	112947161(RSPH3)

TGT:	104575158(RSPH3)

DNE:	112995675(RSPH3)

SCAM:

104143235(RSPH3)

ASN:	102383612(RSPH3)

AMJ:	102573313(RSPH3)

CPOO:

109320079(RSPH3)

GGN:	109304776(RSPH3)

PSS:	102463130(RSPH3)

CMY:	102937496(RSPH3)

CCAY:

125634010(RSPH3)

CPIC:

101952839(RSPH3)

TST:	117874799(RSPH3)

CABI:

116833363(RSPH3)

MRV:	120400938(RSPH3)

ACS:	100557535(rsph3)

ASAO:

132775079(RSPH3) 132781751

PVT:	110072461 110087600(RSPH3)

SUND:

121925053(RSPH3) 121937078

PBI:	103050126(RSPH3) 103056482

PMUR:

107288253(RSPH3) 107295872

CTIG:

120313817 120314819(RSPH3)

TSR:	106541658(RSPH3) 106545553

PGUT:

117656221 117671381(RSPH3)

APRI:

131188450 131192665(RSPH3)

PTEX:

113439226(RSPH3) 113451101

VKO:	123017604 123030466(RSPH3)

PMUA:

114588360 114593355(RSPH3)

PRAF:

128405790 128410704(RSPH3)

ZVI:	118082741(RSPH3) 118087995

HCG:	128344378(RSPH3) 128346133

GJA:	107106838(RSPH3)

STOW:

125437582(RSPH3)

EMC:	129324632(RSPH3) 129330828

XLA:	100158369(rsph3.L)

XTR:	407929(rsph3)

NPR:	108793475(RSPH3)

RTEM:

120935352 120937381(RSPH3)

BBUF:

120997128(RSPH3)

BGAR:

122935767(RSPH3)

PWL:	138295943(RSPH3)

MUO:	115466864(RSPH3)

GSH:	117358233(RSPH3)

DRE:	562259(rsph3)

SRX:	107745291(rsph3)

SANH:

107685760(rsph3)

CCAR:

109099782(rsph3)

CAUA:

113121216(rsph3)

CGIB:

127984285

PTET:

122325123(rsph3)

LROH:

127182747(rsph3)

OMC:	131527408(rsph3)

PPRM:

120493380(rsph3)

RKG:	130096045(rsph3)

MAMB:

125279001(rsph3)

CIDE:

127502284

CERY:

137018672(rsph3)

MASI:

127415859

TROS:

130566374(rsph3)

TDW:	130434491(rsph3)

PDAB:

135750141(rsph3)

IPU:

108270820

IFU:	128613973(rsph3)

PHYP:

113530191(rsph3)

SMEO:

124391454(rsph3)

TFD:	113645435(rsph3) 113663718

TVC:	132858887 132859436 132860154

CGAR:

128523963 128542712(rsph3)

NGRA:

132899029(rsph3)

TRN:	134334459(rsph3)

AMEX:

103033990(rsph3) 111193056 111193670 125802222 125802223 125802224

CMAO:

118815847(rsph3)

EEE:	113571966(rsph3)

CHAR:

105894444(rsph3)

TRU:	101062780 101075889 115249649

TFS:	130515877(rsph3) 130533639

TNG:	GSTEN00020319G001 GSTEN00030718G001

LCO:	104931241(rsph3)

NCC:	104960190(rsph3)

TBEN:

117487022(rsph3)

CGOB:

115003638(rsph3)

PGEO:

117440095(rsph3)

GACU:

117562348(rsph3)

EMAC:

134877067(rsph3)

ELY:	117271024(rsph3)

EFO:	125896964(rsph3)

PLEP:

121955687(rsph3)

SLUC:

116066457(rsph3)

ECRA:

117961919(rsph3)

ESP:	116706087(rsph3)

PFLV:

114573521(rsph3)

GAT:	120808539(rsph3)

PPUG:

119194774(rsph3)

AFB:	129107452(rsph3)

CLUM:

117727906(rsph3)

PSWI:

130202277(rsph3)

CANA:

137785712(rsph3)

CVE:	137892306(rsph3)

MSAM:

119908803(rsph3)

SCHU:

122863480(rsph3)

CUD:	121521689(rsph3)

SPUL:

138585278(rsph3)

LMIX:

132984557(rsph3)

ALAT:

119012148(rsph3)

ASTR:

137613352(rsph3) 137613811

MZE:	101479996(rsph3)

ONL:	100692798(rsph3)

OAU:	116324193(rsph3)

OLA:

101175526

OML:	112139944 112155552

CSAI:

133420703 133464792(rsph3)

XMA:	102229600(rsph3)

XCO:	114158167(rsph3)

XHE:	116734074(rsph3)

PRET:

103457413(rsph3)

PFOR:

103133849(rsph3)

PLAI:

106955315(rsph3)

PMEI:

106924996(rsph3)

GAF:	122825740(rsph3)

PPRL:

129375348(rsph3)

CVG:	107093147(rsph3)

CTUL:

119787852(rsph3)

GMU:	124882280(rsph3)

NFU:	107386367(rsph3)

KMR:	108233429(rsph3)

ALIM:

106522642(rsph3)

NWH:	119417927(rsph3)

AOCE:

111574126(rsph3) 129350219

EJA:	138214683(rsph3)

BFRE:

138633795(rsph3)

MCEP:

124999198(rsph3)

CSEM:

103380872(rsph3)

POV:	109627964(rsph3)

SSEN:

122770948 122772510 122774717 122782104 122783765(rsph3)

SSOE:

131443789(rsph3) 131459903 131467406 131471738

HHIP:

117758099 117758100

HSP:	118099495 118099592

PPLT:

128460232 128460655

SMAU:

118290576(rsph3)

LCF:

108895973

SDU:	111216354(rsph3)

SLAL:

111661416(rsph3)

XGL:	120789126(rsph3)

HCQ:	109508047 109525109

SSCV:

125979403 125989943(rsph3)

SBIA:

133490895 133496406(rsph3)

PEE:	133413478 133417050(rsph3)

PTAO:

133468065(rsph3) 133489925

BPEC:

110154429(rsph3)

ENY:	140377598(rsph3)

MALB:

109962402(rsph3)

BSPL:

114849912(rsph3)

SJO:	128376859(rsph3)

SSCO:

133997971(rsph3)

GMH:	115534112(rsph3)

SASA:

106571206(rsph3)

STRU:

115175011(rsph3)

OTW:	112249958(rsph3)

OMY:	110529415(rsph3)

OGO:	123991571(rsph3)

ONE:	115107586(rsph3)

OKI:	109900573(rsph3)

OKE:	118371910(rsph3)

OMM:	135506140(rsph3)

OCLA:

139415531

SALP:

111954057(rsph3)

SNH:	120024522(rsph3)

CCLU:

121552752(rsph3)

ELS:	105015329(rsph3)

OEP:	134025481(rsph3)

SFM:	108929214 108929329

PKI:	111858034(rsph3)

AANG:

118229137(rsph3)

AROT:

135257758(rsph3)

CCOG:

133129534(rsph3)

LOC:	102689649(rsph3)

PSPA:

121315883(rsph3)

ARUT:

117402674(rsph3)

PSEX:

120516870(rsph3) 120538627

LCM:	102363996(RSPH3)

CMK:	103178903(rsph3)

RTP:	109935955(rsph3)

CPLA:

122552925(rsph3)

HOC:	132819457(rsph3)

LERI:

129699580(rsph3)

PMRN:

116955483(RSPH3)

LRJ:	133357045(RSPH3)

BFO:

118422879

BBEL:

109469426

CIN:	445625(rsp3)

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG32392(Rsph3)

DER:

6544846

DSE:

6611057

DSI:	Dsimw501_GD13109(Dsim_GD13109)

DYA:	Dyak_GE20467

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI12376

DAZ:

108614167

DNV:

108650409

DHE:

111601107

DVI:	6623737(Rsph3)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135953888(Rsph3)

GFS:	119632334 119632603 119641409

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ002223

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139102274(Rsph3)

TLN:	139810560(Rsph3)

HST:

DQU:

CFO:

FEX:

PMEC:

138939850(Rsph3)

LHU:	105677145(Rsph3)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:	124224223(Rsph3)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138132209(Rsph3)

DPA:

109536062

ESIM:

136417085(Rsph3)

EFOR:

136342273(Rsph3)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:	114340691 126891717

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213659

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137931143(Rsph3)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CCRN:

API:

DNX:

AGS:	114130240 126549327

RMD:

113553858

ACOO:

126834949 126836991 126845428

DVT:

126904477

BTAB:

109030006

DCI:	103511440 103511854 113472122

CLEC:

106669178

HHAL:

106686854 106690754

NLU:	111044663 111056219

HVI:	124357152 124371024

MQU:	128986738 128986979

PHU:	Phum_PHUM605300

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138704648(Rsph3)

BROR:

134528165 134528929

IEL:

124161025

HAMR:

139687153(Rsph3)

FCD:

110846844

DMK:

116930012

EAF:

111697121

LSM:	121115729(Rsph3)

PPOI:

119099994

CSCU:

111614305

CVS:	136977906(Rsph3)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

HRO:	HELRODRAFT_67265

LGI:	LOTGIDRAFT_130261

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115230023 115231653

LJP:

135482112

LAK:

106172118

SMM:	Smp_170010

SHX:	MS3_00008626(RSPH3)

OVI:	T265_05347

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_56411

AQU:

105312519

SMO:	SELMODRAFT_450296(RSP3)

PPP:

112284492

CRE:	CHLRE_06g291700v5

VCN:	VOLCADRAFT_106096

MNG:

MNEG_0428

MIS:	MICPUN_60075(RSP3)

MPP:	MICPUCDRAFT_50276(RSP1)

MBR:	MONBRDRAFT_31127

SRE:	PTSG_04734

TGO:	TGME49_254180

BBES:

BESB_012770

TET:	TTHERM_00418270

PTM:	GSPATT00038306001

AAF:	AURANDRAFT_3281

PIF:	PITG_12600

PSOJ:

PHYSODRAFT_296879

SPAR:

SPRG_01063

TBR:	Tb11.47.0034

TBG:	TbgDal_XI1220

TCR:	506721.20 511445.20

LMA:	LMJF_27_0520

LIF:	LINJ_27_2530

LMI:	LMXM_27_0520

LMAT:

92513448(LSCM1_03394)

LBZ:	LBRM_27_0630

LPAN:

LPMP_270510

LOI:	92360046(LSCM4_04123)

LEIS:

94179951(GH5_04521)

LENR:

94170756(CUR178_03514)

LEIN:

94187680(JIQ42_04012)

PHET:

94289311(JKF63_03214)

NGR:	NAEGRDRAFT_64930

TVA:	4769056(TVAGG3_1027290)

SSAO:

94295866(SS50377_21843)

EHX:	EMIHUDRAFT_252544

GTT:	GUITHDRAFT_85021

» show all

Reference

PMID:26073779

Authors

Jeanson L, Copin B, Papon JF, Dastot-Le Moal F, Duquesnoy P, Montantin G, Cadranel J, Corvol H, Coste A, Desir J, Souayah A, Kott E, Collot N, Tissier S, Louis B, Tamalet A, de Blic J, Clement A, Escudier E, Amselem S, Legendre M

Title

RSPH3 Mutations Cause Primary Ciliary Dyskinesia with Central-Complex Defects and a Near Absence of Radial Spokes.

Journal

Am J Hum Genet 97:153-62 (2015)
DOI:10.1016/j.ajhg.2015.05.004

Sequence

[hsa:83861]

LinkDB

DBGET integrated database retrieval system