KEGG ORTHOLOGY: K24006

ORTHOLOGY: K24006

Entry

K24006                      KO

Symbol

PAM

Name

peptidylglycine monooxygenase / peptidylamidoglycolate lyase [EC:1.14.17.3 4.3.2.5]

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K24006  PAM; peptidylglycine monooxygenase / peptidylamidoglycolate lyase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.17  With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.17.3  peptidylglycine monooxygenase
     K24006  PAM; peptidylglycine monooxygenase / peptidylamidoglycolate lyase
4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.5  peptidylamidoglycolate lyase
     K24006  PAM; peptidylglycine monooxygenase / peptidylamidoglycolate lyase

Other DBs

GO:	0004504 0004598

Genes

HSA:

5066(PAM)

PTR:	461974(PAM)

PPS:	100970635(PAM)

GGO:	101148887(PAM)

PON:	100449730(PAM)

PPYG:

129037163(PAM)

NLE:	100603954(PAM)

HMH:	116470968(PAM)

SSYN:

129492549(PAM)

MCC:	707733(PAM)

MCF:	101926659(PAM)

MTHB:

126957228

MNI:	105471068(PAM)

CSAB:

103244283(PAM)

CATY:

105576668(PAM)

PANU:

101026672(PAM)

TGE:	112626915(PAM)

MLEU:

105554887(PAM)

RRO:	104669199(PAM)

RBB:	108527716(PAM)

TFN:	117064857(PAM)

PTEH:

111542665(PAM)

CANG:

105524723(PAM)

CJC:	100396001(PAM)

SBQ:	101034151(PAM)

CIMI:

108291406(PAM)

ANAN:

105722350(PAM)

CSYR:

103263009(PAM)

MMUR:

105875983(PAM)

LCAT:

123648435(PAM)

PCOQ:

105807623(PAM)

OGA:	100956802(PAM)

MMU:	18484(Pam)

MCAL:

110305227(Pam)

MPAH:

110321660(Pam)

RNO:	25508(Pam)

MCOC:

116088825(Pam)

ANU:	117722233(Pam)

ASYL:

127692343(Pam)

MUN:	110540758(Pam)

CGE:	100770162(Pam)

MAUA:

101829991(Pam)

PROB:

127226743(Pam)

PLEU:

114699806(Pam)

MORG:

121433406(Pam)

MFOT:

126508296

AAMP:

119820391(Pam)

NGI:	103738185(Pam)

HGL:	101716909(Pam)

CPOC:

100713254(Pam)

CCAN:

109689129(Pam) 109698017

DORD:

105989825(Pam)

DSP:	122117119(Pam)

DMER:

138832862(Pam)

PLOP:

125339850(Pam)

NCAR:

124986502

MMMA:

107140778(Pam)

ITI:	101964848(Pam)

OCU:

100352005

OPI:	101526566(PAM)

TUP:	102499925(PAM)

GVR:	103593467(PAM)

CFA:	479145(PAM)

CLUD:

112654112(PAM)

VVP:	112915565(PAM)

VLG:	121489468(PAM)

NPO:	129501613(PAM)

AML:	100484534(PAM)

UMR:	103656467(PAM)

UAH:	113255028(PAM)

UAR:	123799268(PAM)

ELK:

111148403

LLV:

125101073

MPUF:

101671790(PAM)

MNP:	132028823(PAM)

MLK:	131832499(PAM)

NVS:	122917187(PAM)

ORO:	101383156(PAM)

EJU:	114208638(PAM)

ZCA:	113929120(PAM)

MLX:	118017056(PAM)

NSU:	110590755(PAM)

LWW:	102745099(PAM)

FCA:	101084598(PAM)

PYU:	121012392(PAM)

PCOO:

112860269(PAM)

PBG:	122491636(PAM)

PVIV:

125161563(PAM)

LRUF:

124519496

LGF:	123609071(PAM)

AJU:

106982276

PTG:	102961161(PAM)

PPAD:

109267636(PAM)

PUC:

125934337

PLEZ:

122223487(PAM)

HHV:	120220005(PAM)

BTA:	280890(PAM)

BOM:	102271872(PAM)

BIU:	109562372(PAM)

BBUB:

102409727(PAM)

BBIS:

104982553(PAM)

CHX:	102190130(PAM)

OAS:	101112815(PAM)

BTAX:

128051451(PAM)

CSUM:

138085571(PAM)

ODA:	120863478(PAM)

CCAD:

122439492(PAM)

MREE:

136158164(PAM)

OVR:	110135527(PAM)

MBEZ:

129558554(PAM)

SSC:	100526040(PAM)

CFR:	102509591(PAM)

CBAI:

105082012(PAM)

CDK:	105103083(PAM)

VPC:	102529765(PAM)

BACU:

103008694(PAM)

BMUS:

118893484(PAM)

LVE:	103088789(PAM)

OOR:	101274063(PAM)

LALB:

132516970(PAM)

GMF:	115848147(PAM)

DLE:	111183960(PAM)

PCAD:

102993897(PAM)

PSIU:

116750498(PAM)

PPHC:

136120714(PAM)

NASI:

112396130(PAM)

ECB:	791244(PAM)

EPZ:	103555847(PAM)

EAI:	106831159(PAM)

MYB:	102257709(PAM)

MYD:	102752613(PAM)

MMYO:

118655718(PAM)

MLF:	102422620(PAM)

MDT:	132233389(PAM)

MYUM:

139008786(PAM)

PKL:	118703757(PAM)

EFUS:

103288742(PAM)

MNA:	107544178(PAM)

DRO:	112307140(PAM)

SHON:

118977247(PAM)

AJM:	119047249(PAM)

PDIC:

114494537(PAM)

PHAS:

123818032(PAM)

MMF:	118641919(PAM)

PPAM:

129083931(PAM)

HAI:	109394174(PAM)

RFQ:	117024680(PAM)

PALE:

102894575(PAM)

PGIG:

120590776(PAM)

PVP:	105304427(PAM)

RAY:	107509145(PAM)

MJV:	108391703(PAM)

TOD:	119260954(PAM)

SARA:

101547265(PAM)

SFUM:

130015808(PAM)

SETR:

126001926(PAM)

LAV:	100655604(PAM)

TMU:

101356870

ETF:	101662573(PAM)

DNM:	101428897(PAM)

MDO:	100030601(PAM)

GAS:	123236274(PAM)

SHR:	100929728(PAM)

AFZ:

127560527

PCW:	110199219(PAM)

TVP:	118830590(PAM)

PBRV:

138161305(PAM)

MLAO:

141502519(PAM)

OAA:	100073355(PAM)

TACU:

119939176(PAM)

GGA:	427274(PAM)

PCOC:

116229802(PAM)

CJO:	107306340(PAM)

TPAI:

128089489(PAM)

LMUT:

125687282(PAM)

NMEL:

110389678(PAM)

APLA:

101795983(PAM)

ACYG:

106043740(PAM)

CATA:

118260084(PAM)

AFUL:

116500419(PAM)

TGU:	100227923(PAM)

LSR:	110477851(PAM)

SCAN:

103822855(PAM)

PMOA:

120500582(PAM)

OTC:	121332561(PAM)

PRUF:

121355586(PAM)

ATRC:

139600483(PAM)

GFR:	102039677(PAM)

FAB:	101821831(PAM)

OMA:	130264919(PAM)

PHI:	102114573(PAM)

PMAJ:

107215969(PAM)

CCAE:

111940620(PAM)

CCW:	104693194(PAM)

CBRC:

103613059(PAM)

ETL:	114064047(PAM)

ZAB:	102069666(PAM)

ZLE:	135459288(PAM)

SVG:	106863061(PAM)

MMEA:

130586850

HRT:	120765045(PAM)

SATI:

136374135(PAM)

CCIC:

134056140(PAM)

FPG:	101920860(PAM)

FCH:	102052743(PAM)

CCRI:

104158631(PAM)

NNT:	104402404(PAM)

SHAB:

115619349(PAM)

ACUN:

113489698(PAM)

TALA:

104363524(PAM)

ACHC:

115336613(PAM)

HALD:

104316339(PAM)

HLE:	104830258(PAM)

AGEN:

126036477

HHAR:

128137836(PAM)

GCL:

127027149

CSTI:

104549454

LDI:	104346787(PAM)

DPUB:

104302573(PAM)

PPUS:

135173628(PAM)

AVIT:

104279353(PAM)

EGZ:	104135057(PAM)

NNI:	104010298(PAM)

PCRI:

104029410(PAM)

PCAO:

104044911(PAM)

PADL:

103920863(PAM)

AFOR:

103903061(PAM)

FGA:	104074433(PAM)

CBOY:

140651094(PAM)

CLV:	102087217(PAM)

CNIC:

136001332(PAM)

PGUU:

104464770(PAM)

PLET:

104619390(PAM)

EHS:	104507079(PAM)

CMAC:

104484951(PAM)

CUCA:

104058390(PAM)

TEO:	104374810(PAM)

BREG:

104629990(PAM)

OHA:	104327527(PAM)

ACAR:

104522283(PAM)

CPEA:

104397259(PAM)

CVF:	104292311(PAM)

RTD:	128902291(PAM)

CRID:

134508998(PAM)

AROW:

112970164(PAM)

NPD:	112951384(PAM)

TGT:	104568553(PAM)

DNE:	112988498 112992418

SCAM:

104140158(PAM)

ASN:	102374229(PAM)

AMJ:	102559599(PAM)

CPOO:

109308144(PAM)

GGN:	109297455(PAM)

PSS:	102462977(PAM)

CMY:	102946187(PAM)

CCAY:

125636433(PAM)

DCC:	119855451(PAM)

CPIC:

101942761(PAM)

TST:	117879396(PAM)

CABI:

116815270(PAM)

MRV:	120407700(PAM)

ACS:	100562563(pam)

ASAO:

132767177(PAM)

PVT:	110079386(PAM)

SUND:

121924102(PAM)

PBI:	103055156(PAM)

CTIG:

120306039(PAM)

TSR:	106548589(PAM)

PGUT:

117674609(PAM)

PCAE:

139313249(PAM)

APRI:

131190111(PAM)

PTEX:

113448749(PAM)

NSS:	113415426(PAM)

VKO:	123031660(PAM)

PMUA:

114606841(PAM)

PRAF:

128423318(PAM)

ZVI:	118076918(PAM)

HCG:	128343029(PAM)

GJA:	107121208(PAM)

STOW:

125436547(PAM)

EMC:	129334290(PAM)

XLA:	379207(pam.L) 397736(pam.S)

XTR:	100170159(pam)

NPR:	108797815(PAM)

RTEM:

120931440(PAM)

ACAT:

141137263(PAM)

BBUF:

120992549(PAM)

BGAR:

122924652(PAM)

DTC:	141049259(PAM)

PWL:	138285730(PAM)

MUO:	115463171(PAM)

GSH:	117352610(PAM)

DRE:	570822(pam)

SRX:	107715844 107737006

SANH:

107670040 107702561

SGH:	107558261(pam) 107560403

CCAR:

109097266 109098036

CAUA:

113053993 113109552

CGIB:

127966314 128021433

PTET:

122352678(pam)

LROH:

127171703(pam)

GRF:	141298780(pam)

OMC:	131547997(pam)

PPRM:

120483160(pam)

MAMB:

125255806(pam)

CIDE:

127520520

MASI:

127432330 127433275

TROS:

130545926(pam)

TDW:	130411485(pam)

MANU:

129447594(pam)

PDAB:

135718254(pam)

IPU:

108277198

IFU:	128619989(pam)

PHYP:

113543505(pam)

SMEO:

124393835(pam)

TFD:	113639276(pam)

TVC:	132863745(pam)

CGAR:

128545571(pam)

NGRA:

132873319(pam)

TRN:	134332132(pam)

AMEX:

103031431(pam)

CMAO:

118824741(pam)

EEE:	113576732(pam)

CHAR:

105894612(pam)

SPIL:

134100533(pam)

TRU:	101062613(pam)

TFS:	130516843(pam)

TNG:	GSTEN00013653G001

LCO:	104938829(pam)

TBEN:

117474446(pam)

CGOB:

115017065(pam)

PGEO:

117455911(pam)

GACU:

117557435(pam)

EMAC:

134868393(pam)

ELY:	117269835(pam)

EFO:	125905793(pam)

PLEP:

121960283(pam)

SLUC:

116041373(pam)

ECRA:

117958843(pam)

PFLV:

114570620(pam)

GAT:	120831508(pam)

PPUG:

119226240(pam)

AFB:	129102660(pam)

CLUM:

117740491(pam)

PSWI:

130205500(pam)

CANA:

137783438(pam)

CVE:	137868809(pam)

MSAM:

119914308(pam)

SCHU:

122865869(pam)

CUD:	121525000(pam)

SPUL:

138609586(pam)

LMIX:

132968519(pam)

ALAT:

119030296(pam)

ASTR:

137608003(pam)

MZE:	101484633(pam)

ONL:	100700800(pam)

OAU:	116319154(pam)

OLA:	101164528(pam)

OML:	112140341(pam)

CSAI:

133455498(pam)

XMA:	102227462(pam)

XCO:	114149523(pam)

XHE:	116724732(pam)

PRET:

103473165(pam)

PFOR:

103152322

PLAI:

106947015(pam)

PMEI:

106922489(pam)

GAF:	122819675(pam)

PPRL:

129379781(pam)

CVG:	107098487(pam)

CTUL:

119797739(pam)

GMU:	124872307(pam)

NFU:	107395057(pam)

KMR:	108246466(pam)

ALIM:

106522199(pam)

NWH:	119424389(pam)

AOCE:

111579145(pam)

EJA:	138210121(pam)

BFRE:

138635598(pam)

MCEP:

124996364(pam)

CSEM:

103389193(pam)

POV:	109637635(pam)

SSEN:

122758574(pam)

SSOE:

131445926(pam)

HHIP:

117771409(pam)

HSP:	118098063(pam)

PPLT:

128424769(pam)

SMAU:

118284799(pam)

LCF:

108877750

SDU:	111221118(pam)

SLAL:

111659622(pam)

XGL:	120806189(pam)

HCQ:	109530660(pam)

SSCV:

125979803(pam)

SBIA:

133490609(pam)

PEE:	133414017(pam)

PTAO:

133465262(pam)

BPEC:

110161642(pam)

ENY:	140367496(pam)

MALB:

109960744(pam)

BSPL:

114867236(pam)

SJO:	128379787(pam)

SSCO:

133994864(pam)

GMH:	115542060(pam)

SASA:

106571984(pam)

STRU:

115160105(pam)

OTW:	112219988(pam)

OMY:	110523161(pam)

OGO:	123989512(pam)

ONE:	115118014(pam)

OKI:	109868844(pam)

OKE:	118387260(pam)

OMM:	135518378(pam)

OCLA:

139408310

SALP:

111961960(pam)

SNH:	120025478(pam)

CCLU:

121581954(pam)

ELS:	105020460(pam)

OEP:	134038821(pam)

SFM:	108929922(pam)

PKI:	111835769(pam)

AANG:

118212765(pam)

AROT:

135240145(pam)

CCOG:

133141679(pam)

LOC:	102682623(pam)

PSPA:

121302893(pam) 121315078

ARUT:

117409376 117963343

PSEX:

120532663(pam)

LCM:	102348819(PAM)

CMK:	103178402(pam)

RTP:	109919477(pam)

CPLA:

122559877(pam)

HOC:	132823331(pam)

LERI:

129695861(pam)

HAKA:

140739520(pam)

PMRN:

116950708 116954932

LRJ:	133360938(PAM)

BFO:	118407264 118409685

BBEL:

109470824 109482227

CIN:

100186640

SCLV:

120333720 120334207

SPU:	579753 587198

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

FCD:

DPX:	DAPPUDRAFT_330720

DMK:	116930770 123466817

DPZ:

AFRA:

PVM:

PJA:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

PORN:

HAZT:

EAF:	111695161 111695791

LSM:

PPOI:

DSV:

RMP:

DPTE:

DFR:

CSCU:

CVS:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_T19B4.1(pamn-1)

CBR:	CBG_14919(Cbr-pamn-1)

CRQ:	GCK72_001307

NAI:	NECAME_00981

LOA:	LOAG_02126

HRO:	HELRODRAFT_90150

LGI:	LOTGIDRAFT_128636

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:	124146994 124147038

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_156530

SHX:	MS3_00006564

OVI:	T265_08837

EGL:

EGR_00446

LLON:

135483295

NVE:	5505959 5513959

EPA:	110253509 110253517

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114522559 114541151

XEN:	124452262 124454721

HMG:

100212200

HSY:	130640814 130643790 130646165

RES:	135687062 135687547

TAD:	TRIADDRAFT_63754

OLU:	OSTLU_15206(PAM1)

OTA:	OT_ostta04g04860

BPG:	Bathy08g04470

MPP:	MICPUCDRAFT_60313

» show all

Reference

PMID:12699694

Authors

Satani M, Takahashi K, Sakamoto H, Harada S, Kaida Y, Noguchi M

Title

Expression and characterization of human bifunctional peptidylglycine alpha-amidating monooxygenase.

Journal

Protein Expr Purif 28:293-302 (2003)
DOI:10.1016/s1046-5928(02)00684-8

Sequence

[hsa:5066]

Reference

PMID:11028916

Authors

Prigge ST, Mains RE, Eipper BA, Amzel LM

Title

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function.

Journal

Cell Mol Life Sci 57:1236-59 (2000)
DOI:10.1007/PL00000763

LinkDB

DBGET integrated database retrieval system