KEGG ORTHOLOGY: K24015

ORTHOLOGY: K24015

Entry

K24015                      KO

Symbol

UNC80

Name

protein unc-80

Disease

H01922

Infantile hypotonia with psychomotor retardation and characteristic facies

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K24015  UNC80; protein unc-80
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Sodium leak channel, non-selective
   K24015  UNC80; protein unc-80

Other DBs

TC:	1.A.1.11.15

Genes

HSA:	285175(UNC80)

PTR:	459911(UNC80)

PPS:	100990194(UNC80)

GGO:	101129967(UNC80)

PON:	100438941(UNC80)

PPYG:

129031212(UNC80)

NLE:	100592472(UNC80)

HMH:	116810367(UNC80)

SSYN:

129488363(UNC80)

MCC:	713007(UNC80)

MCF:	102127896(UNC80)

MTHB:

126932514

MNI:	105481129(UNC80)

CSAB:

103217749(UNC80)

CATY:

105580131(UNC80)

PANU:

101023667(UNC80)

TGE:	112636082(UNC80)

MLEU:

105529400(UNC80)

RRO:	104655502(UNC80)

RBB:	108540356(UNC80)

TFN:	117094583(UNC80)

PTEH:

111545966(UNC80)

CANG:

105504772(UNC80)

CJC:	100413919(UNC80)

SBQ:	101053190(UNC80)

CIMI:

108316729(UNC80)

ANAN:

105712667(UNC80)

CSYR:

103251760(UNC80)

MMUR:

105863903(UNC80)

LCAT:

123643591(UNC80)

ERUF:

138382967(UNC80)

PCOQ:

105823916(UNC80)

OGA:	100952262(UNC80)

MMU:	329178(Unc80)

MCAL:

110294217(Unc80)

MPAH:

110321692(Unc80)

RNO:	689991(Unc80)

MCOC:

116088523(Unc80)

ANU:	117705702(Unc80)

ASYL:

127692915(Unc80)

MUN:	110563139(Unc80)

CGE:	100759311(Unc80)

MAUA:

101836525(Unc80)

PROB:

127226394(Unc80)

PLEU:

114693622(Unc80)

PMAV:

102928381(Unc80)

MORG:

121433500(Unc80)

MFOT:

126508784

AAMP:

119820433(Unc80)

CNL:	130869377(Unc80)

NGI:	103744459(Unc80)

HGL:	101701377(Unc80)

CPOC:

100722465(Unc80)

CCAN:

109691992(Unc80)

DORD:

105981610(Unc80)

DSP:	122107507(Unc80)

DMER:

138824257(Unc80)

PLOP:

125350342(Unc80)

NCAR:

124979810

MMMA:

107138381(Unc80)

ITI:	101955559(Unc80)

OCU:

100339726

OPI:	101535327(UNC80)

OCZ:	121159397(UNC80)

TUP:	102490656(UNC80)

GVR:	103588659(UNC80)

CFA:	488505(UNC80)

CLUD:

112656342(UNC80)

VVP:	112922598(UNC80)

VLG:	121480797(UNC80)

NPO:	129522872(UNC80)

AML:	100467089(UNC80)

UMR:	103659962(UNC80)

UAH:	113250511(UNC80)

UAR:	123798051(UNC80)

ELK:

111151748

LLV:

125095482

MPUF:

101679124(UNC80)

MNP:	132013510(UNC80)

MLK:	131827506(UNC80)

NVS:	122902257(UNC80)

ORO:	101375669(UNC80)

EJU:	114215975(UNC80)

ZCA:	113920529(UNC80)

MLX:	118012090(UNC80)

NSU:	110592085(UNC80)

LWW:	102727498(UNC80)

FCA:	101098246(UNC80)

PYU:	121031002(UNC80)

PCOO:

112870295(UNC80)

PBG:	122481716(UNC80)

PVIV:

125172774(UNC80)

LRUF:

124515962

LGF:	123599399(UNC80)

AJU:

106976297

PTG:	102964352(UNC80)

PPAD:

109265130(UNC80)

PUC:

125911244

PLEZ:

122228197(UNC80)

HHV:	120243745(UNC80)

BTA:	536610(UNC80)

BOM:	102265563(UNC80)

BIU:	109575662(UNC80)

BBUB:

102404910(UNC80)

BKE:	129647316(UNC80)

BBIS:

105003850(UNC80)

CHX:	102168868(UNC80)

OAS:	101122170(UNC80)

BTAX:

128069319(UNC80)

CSUM:

138075705(UNC80)

ODA:	120854541(UNC80)

CCAD:

122426583(UNC80)

MREE:

136163234(UNC80)

OVR:	110135705(UNC80)

MBEZ:

129538390(UNC80)

SSC:	100522957(UNC80)

CFR:	102504661(UNC80)

CBAI:

105072950(UNC80)

CDK:	105093546(UNC80)

VPC:	102535499(UNC80)

BACU:

102999759(UNC80)

BMUS:

118898283(UNC80)

LVE:

103072412

OOR:	101281291(UNC80)

LALB:

132521660(UNC80)

GMF:	115851350(UNC80)

DDP:	132428029(UNC80)

DLE:	111172043(UNC80)

PCAD:

102994743(UNC80)

PSIU:

116756603(UNC80)

PPHC:

136125310(UNC80)

NASI:

112395256(UNC80)

ECB:	100049923(UNC80)

EPZ:	103560555(UNC80)

EAI:	106848064(UNC80)

MYB:	102238915(UNC80)

MYD:	102766510(UNC80)

MMYO:

118661262(UNC80)

MLF:	102441668(UNC80)

MDT:	132238182(UNC80)

MYUM:

139014974(UNC80)

PKL:	118709019(UNC80)

EFUS:

103289350(UNC80)

MNA:	107524804(UNC80)

DRO:	112307786(UNC80)

SHON:

118984286(UNC80)

AJM:	119064386(UNC80)

PDIC:

114495687(UNC80)

PHAS:

123829145(UNC80)

MMF:	118625592(UNC80)

PPAM:

129080381(UNC80)

HAI:	109390440(UNC80)

RFQ:	117025767(UNC80)

PALE:

102892875(UNC80)

PGIG:

120587598(UNC80)

PVP:	105298388(UNC80)

RAY:	107503683(UNC80)

MJV:	108394308(UNC80)

TOD:	119256161(UNC80)

SARA:

101555164(UNC80)

SFUM:

130021074(UNC80)

SETR:

126022968(UNC80)

LAV:	100657325(UNC80)

TMU:

101360230

ETF:	101650638(UNC80)

DNM:	101437655(UNC80)

MDO:	100013259(UNC80)

GAS:	123240114(UNC80)

SHR:	100932697(UNC80)

AFZ:

127553157

PCW:	110223328(UNC80)

TVP:	118847134(UNC80)

PBRV:

138151677(UNC80)

MLAO:

141490994(UNC80)

OAA:	103169586(UNC80)

TACU:

119945384(UNC80)

GGA:	424003(UNC80)

PCOC:

116235921(UNC80)

MGP:	100540125(UNC80)

CJO:	107316455(UNC80)

TPAI:

128076842(UNC80)

LMUT:

125696812(UNC80)

NMEL:

110399510(UNC80)

APLA:

101801718(UNC80)

AACU:

137858509(UNC80)

ACYG:

106034503(UNC80)

CATA:

118257675(UNC80)

AFUL:

116490478(UNC80)

TGU:	100230000(UNC80)

LSR:	110471691(UNC80)

SCAN:

103814569(UNC80)

PMOA:

120511541(UNC80)

OTC:	121339683(UNC80)

PRUF:

121364420(UNC80)

ATRC:

139593481(UNC80)

GFR:	102038531(UNC80)

FAB:	101818520(UNC80)

OMA:	130255345(UNC80)

PHI:	102107438(UNC80)

PMAJ:

107207422(UNC80)

CCAE:

111931886(UNC80)

CCW:

104689869

CBRC:

103624288(UNC80)

ACOE:

138113511

ETL:	114059415(UNC80)

ZAB:	102068270(UNC80)

ZLE:	135450517(UNC80)

ACHL:

103801476(UNC80)

SVG:	106863943(UNC80)

MMEA:

130588878(UNC80)

HRT:	120754889(UNC80)

SATI:

136363307(UNC80)

CFAI:

136293114(UNC80)

CCIC:

134052362(UNC80)

FPG:	101920270(UNC80)

FCH:	102059918(UNC80)

CCRI:

104166756

NNT:	104409937(UNC80)

SHAB:

115608231(UNC80)

ACUN:

113482446(UNC80)

SURA:

141945095(UNC80)

TALA:

104365403(UNC80)

ACHC:

115342740(UNC80)

HALD:

104318974(UNC80)

HLE:	104841526(UNC80)

AGEN:

126040780

HHAR:

128144008(UNC80)

BBUT:

142031075(UNC80)

GCL:

127018424

MNB:	103776170(UNC80)

DPUB:

104298417(UNC80)

PPUS:

135186276(UNC80)

AVIT:

104272827(UNC80)

BRHI:

104500385(UNC80)

EGZ:	104124204(UNC80)

NNI:	104010074(UNC80)

PCRI:

104034840(UNC80)

PADL:

103921652(UNC80)

AFOR:

103900398(UNC80)

FGA:

104083239

CBOR:

142083782(UNC80)

GSTE:

104256556(UNC80)

CBOY:

140657400(UNC80)

MAME:

142414828(UNC80)

CLV:	102096356(UNC80)

CNIC:

135990178(UNC80)

MUI:	104543631(UNC80)

PGUU:

104469772

PLET:

104616892(UNC80)

EHS:	104512682(UNC80)

CUCA:

104064551(UNC80)

TEO:

104376710

BREG:

104630653(UNC80)

GAME:

129207855(UNC80)

OHA:	104338577(UNC80)

ACAR:

104518675(UNC80)

CPEA:

104388081(UNC80)

CVF:	104288747(UNC80)

RTD:	128913124(UNC80)

CRID:

134518882(UNC80)

LMIC:

141746501(UNC80)

NARQ:

141462882(UNC80)

AAM:	106492372(UNC80)

AROW:

112976858(UNC80)

NPD:	112954306(UNC80)

TGT:	104575231(UNC80)

DNE:	112993439(UNC80)

SCAM:

104153012(UNC80)

ASN:	102388186(UNC80)

AMJ:	102565011(UNC80)

CPOO:

109322609(UNC80)

GGN:	109301993(UNC80)

PSS:	102446294(UNC80)

CIZ:	142016651(UNC80)

CMY:	102941604(UNC80)

CCAY:

125644745(UNC80)

LKP:	140895864(UNC80)

NDS:	141996175(UNC80)

DCC:	119863269(UNC80)

CPIC:

101945955(UNC80)

TST:	117884699(UNC80)

CABI:

116816099(UNC80)

MRV:	120374654(UNC80)

ACS:	100561741(unc80)

ASAO:

132778796(UNC80)

PVT:	110072418(UNC80)

SUND:

121914168(UNC80)

PBI:	103056591 103064014(UNC80)

PMUR:

107286248

CTIG:

120312332(UNC80)

PGUT:

117674564(UNC80)

PCAE:

139327086(UNC80)

APRI:

131199216(UNC80)

PTEX:

113440933(UNC80)

NSS:	113415668(UNC80)

VKO:	123024350(UNC80)

PMUA:

114583634(UNC80)

PRAF:

128401635(UNC80)

ZVI:	118096598(UNC80)

HCG:	128339464 128339530

GJA:	107119081(UNC80)

STOW:

125426188(UNC80)

EMC:	129323600(UNC80)

XLA:	108701429(unc80.L)

XTR:	779473(unc80)

NPR:	108794428(UNC80)

RTEM:

120943854(UNC80)

ACAT:

141146842(UNC80)

PADS:

140335713(UNC80)

BBUF:

121008462(UNC80)

BGAR:

122945729(UNC80)

DTC:

141054300

PWL:	138285572(UNC80)

MUO:	115474136(UNC80)

GSH:	117361031(UNC80)

DRE:	100536734(unc80)

SRX:	107709567 107733373

SANH:

107677624 107688825

SGH:	107562223 107586360(unc80)

CCAR:

109082946

CAUA:

113096620(unc80)

CGIB:

127959467

PTET:

122346787 122346910

LROH:

127166478

GRF:	141347502(unc80)

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

129450398(unc80)

PDAB:

135717814(unc80)

IPU:

108272372

IFU:

128615401

PHYP:

113538326(unc80)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113574020(unc80)

CHAR:

105905295

SPIL:

134061853

ASAD:

121696861

TRU:	105418828(unc80)

TFS:

130523318

TNG:	GSTEN00015863G001

LCO:	104929361(unc80)

NCC:	104953633(unc80)

TBEN:

117499241

CGOB:

115019077(unc80)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:	116674200(unc80)

PFLV:

114550661(unc80)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:	141785761(unc80)

ALAT:

119015518

ASTR:

137591418

PKLU:

139223640

MZE:	101470347(unc80)

ONL:	100702120(unc80)

OAU:

116332064

OLA:	101166366(unc80)

OML:

112156663

CSAI:

133425206

XMA:	102230646(unc80)

XCO:	114140707(unc80)

XHE:	116715754(unc80)

PRET:

103476829(unc80)

PFOR:

103139212(unc80)

PLAI:

106940519(unc80)

PMEI:

106914876(unc80)

GAF:

122827503

PPRL:

129378690

CVG:	107093617(unc80)

CTUL:

119780808

GMU:

124861581

NFU:	107377232(unc80)

KMR:

108242191

ALIM:

106522869(unc80)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103389550(unc80)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111233919(unc80)

SLAL:

111665290(unc80)

XGL:

120798371

HCQ:	109528401(unc80)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110170912(unc80)

ENY:	140361251(unc80)

MALB:

109968778(unc80)

BSPL:

SJO:

SSCO:

TTY:

GMH:	115538234(unc80)

SASA:

106574930(unc80)

STRU:

115179225 115195176

OTW:

112239191

OMY:	110497049 110514120

OGO:	124010734 124025816

OKI:	109876752 109876945

OKE:

118379616

OCLA:

139396940

SNH:	120033462 120039489

SFON:

129846006

CCLU:

121574679 123487294

ELS:	105023133(unc80)

OEP:

134007846

SFM:	108918899(unc80)

PKI:	111857179(unc80)

AANG:

118214123

AROT:

135240617

CCOG:

133116881

LOC:	102687983(unc80)

PSPA:

121321971 121323429

ARUT:

117426669

PSEX:

120530703

LCM:	102347444(UNC80)

CMK:

103182963

RTP:

109912343

CPLA:

122551900

CPUN:

140481983(unc80)

HOC:

132817546

SCAU:

119960968

LERI:

129698575

HAKA:

140728290(unc80)

PMRN:

116939985(UNC80)

LRJ:	133350246(UNC80)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG18437(unc80)

DER:

6554451

DSE:

6618698

DSI:	Dsimw501_GD21344(Dsim_GD21344)

DYA:	Dyak_GE23751

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22017

DAZ:

108620757

DNV:

108651416

DHE:

111593238

DVI:	6632299(unc80)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:	101899092 101899704

SCAC:

106095776

LCQ:

111683563

LSQ:

119614241

CVJ:	135963849(unc80)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ013258

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108723919(unc80)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139110296(Unc80)

TLN:	139813789(Unc80)

TAME:

143895221(Unc80)

HST:

DQU:

CFO:

FEX:

PMEC:

138944950(Unc80)

LHU:	105671708(unc80)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141537358(Unc80)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124213021(unc80)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138135667(unc80)

DPA:

109544558

ESIM:

136416333(unc80)

EFOR:

136348083(unc80)

SOY:

115884265

RFG:	143202325(unc80)

AGRG:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

BMOR:

BMAN:

MSEX:

DPL:	KGM_211593

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137926975(unc80)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

141434045(unc80)

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106684301(unc80)

NLU:

111059297

LDA:	142328974(unc80)

HVI:

124360589

MQU:

128991485

PHU:	Phum_PHUM244880

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

IEL:

HAMR:

139690859(unc80)

DPX:	DAPPUDRAFT_318531

DMK:

116922735

DPZ:

124340767

AFRA:

136035321

PVM:	113813755(unc80)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123772714(unc80)

PTRU:

123513061

ESN:

126984224

MNZ:

135216070

MRJ:	136849205(unc80)

PORN:

139757418(unc80)

OOT:

143032297

LSM:	121114755(unc80)

PPOI:

119097728 119097729

ISC:

120849056

DSV:

119442285

DALB:

135900267(unc80)

RSAN:

RMP:

OTI:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136990047(unc80)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F25C8.3(unc-80)

CBR:	CBG_05555(Cbr-unc-80)

LGI:	LOTGIDRAFT_232936

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_174230

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

Reference

PMID:19092807

Authors

Lu B, Su Y, Das S, Wang H, Wang Y, Liu J, Ren D

Title

Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80.

Journal

Nature 457:741-4 (2009)
DOI:10.1038/nature07579

Sequence

[mmu:329178]

LinkDB

DBGET integrated database retrieval system