KEGG ORTHOLOGY: K25048

ORTHOLOGY: K25048

Entry

K25048                      KO

Symbol

TMEM106B

Name

transmembrane protein 106B

Disease

H00679

Hypomyelinating leukodystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K25048  TMEM106B; transmembrane protein 106B
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Others
   Others
    K25048  TMEM106B; transmembrane protein 106B

Other DBs

TC:

9.B.23.1

Genes

HSA:	54664(TMEM106B)

PTR:	463266(TMEM106B)

PPS:	100983823(TMEM106B)

GGO:	101126429(TMEM106B)

PON:	100442914(TMEM106B)

PPYG:

129040798(TMEM106B)

NLE:	100590992(TMEM106B)

HMH:	116813592(TMEM106B)

SSYN:

129479451(TMEM106B)

MCC:	694132(TMEM106B)

MCF:	101867009(TMEM106B)

MTHB:

126949985

MNI:	105475600(TMEM106B)

CSAB:

103226474(TMEM106B)

CATY:

105589587(TMEM106B)

PANU:

101011050(TMEM106B)

TGE:	112621436(TMEM106B)

MLEU:

105548495(TMEM106B)

RRO:	104657851(TMEM106B)

RBB:	108526591(TMEM106B)

TFN:	117072317(TMEM106B)

PTEH:

111551068(TMEM106B)

CANG:

105512476(TMEM106B)

CJC:	100399696(TMEM106B)

SBQ:	101043051(TMEM106B)

CIMI:

108301887(TMEM106B)

ANAN:

105716265(TMEM106B)

CSYR:

103255536(TMEM106B)

MMUR:

105867268(TMEM106B)

LCAT:

123647098(TMEM106B)

PCOQ:

105805782(TMEM106B)

OGA:	100942652(TMEM106B)

MMU:	71900(Tmem106b)

MCAL:

110296347(Tmem106b)

MPAH:

110316492(Tmem106b)

RNO:	312132(Tmem106b)

MCOC:

116098584(Tmem106b)

ANU:	117720496(Tmem106b)

ASYL:

127678362(Tmem106b)

MUN:	110541381(Tmem106b)

CGE:	100763634(Tmem106b)

MAUA:

101830463(Tmem106b)

PROB:

127215323(Tmem106b)

PLEU:

114694752 114710477(Tmem106b)

MORG:

121463529(Tmem106b)

MFOT:

126503890

AAMP:

119806761(Tmem106b)

NGI:	103751160(Tmem106b)

HGL:	101703812(Tmem106b)

CPOC:

100715910(Tmem106b)

CCAN:

109697346(Tmem106b)

DORD:

105988412(Tmem106b)

DSP:	122121780(Tmem106b)

PLOP:

125347045(Tmem106b)

NCAR:

124990746

MMMA:

107144476(Tmem106b)

ITI:	101954305(Tmem106b)

OCU:

100356191

OPI:	101519998(TMEM106B)

TUP:	102494031(TMEM106B)

GVR:	103586923(TMEM106B)

CFA:	102155890 482322(TMEM106B)

CLUD:

112668926 112674839(TMEM106B)

VVP:	112923933(TMEM106B)

VLG:	121474675(TMEM106B)

NPO:	129502908(TMEM106B)

AML:	100479101(TMEM106B)

UMR:	103658823(TMEM106B)

UAH:	113260714(TMEM106B)

UAR:	123789231(TMEM106B)

ELK:

111147310

LLV:

125080852

MPUF:

101683305 101693256(TMEM106B)

MNP:	132015910(TMEM106B) 132029053

MLK:	131829440(TMEM106B)

NVS:	122904865(TMEM106B)

ORO:	101382972(TMEM106B)

EJU:	114221605(TMEM106B)

ZCA:	113911234(TMEM106B)

MLX:	118020812(TMEM106B)

NSU:	110580012(TMEM106B)

LWW:	102740858(TMEM106B)

FCA:	101100710(TMEM106B)

PYU:	121026770 121026792

PCOO:

112866752(TMEM106B)

PBG:	122487936(TMEM106B)

PVIV:

125160459(TMEM106B)

LRUF:

124523887

LGF:	123606492(TMEM106B)

AJU:

106983062

PTG:	102956304(TMEM106B)

PPAD:

109263758(TMEM106B)

PUC:

125929950

PLEZ:

122208195(TMEM106B)

HHV:	120248159(TMEM106B)

BTA:	508903(TMEM106B)

BOM:	102265774(TMEM106B)

BIU:	109557260(TMEM106B)

BBUB:

102401158(TMEM106B)

BBIS:

105004507(TMEM106B)

CHX:	102174271(TMEM106B)

OAS:	101122854(TMEM106B)

BTAX:

128046859(TMEM106B)

CSUM:

138080190(TMEM106B)

ODA:	120878018(TMEM106B)

CCAD:

122438149(TMEM106B)

MREE:

136170476(TMEM106B)

OVR:	110124677(TMEM106B)

MBEZ:

129552262(TMEM106B)

SSC:	100512621(TMEM106B)

CFR:	102514591(TMEM106B)

CBAI:

105082486(TMEM106B)

CDK:	105088694(TMEM106B)

VPC:	102537790(TMEM106B)

BACU:

103009754

BMUS:

118900843(TMEM106B)

LVE:

103086338

OOR:	101279112(TMEM106B)

LALB:

132524746(TMEM106B)

DLE:	111181645(TMEM106B)

PCAD:

102975960(TMEM106B)

PSIU:

116759555(TMEM106B)

NASI:

112414587(TMEM106B)

ECB:	100064947(TMEM106B)

EPZ:	103561413(TMEM106B)

EAI:	106829122(TMEM106B)

MYB:	102243724(TMEM106B)

MYD:	102769981(TMEM106B)

MMYO:

118666174(TMEM106B)

MLF:	102424253(TMEM106B)

MDT:	132242987(TMEM106B)

MYUM:

139016380(TMEM106B)

PKL:	118714243(TMEM106B)

EFUS:

103292432(TMEM106B)

MNA:	107541736(TMEM106B)

DRO:	112319847(TMEM106B)

SHON:

118987310(TMEM106B)

AJM:	119065354(TMEM106B)

PDIC:

114507675(TMEM106B)

PHAS:

123811455(TMEM106B)

MMF:	118620084(TMEM106B)

PPAM:

129063440(TMEM106B)

RFQ:	117012131(TMEM106B)

PALE:

102886993(TMEM106B)

PGIG:

120602288(TMEM106B)

PVP:	105294007(TMEM106B)

RAY:	107518747(TMEM106B)

MJV:	108401133(TMEM106B)

TOD:	119242857(TMEM106B)

SARA:

101545637(TMEM106B)

SFUM:

130027397(TMEM106B)

SETR:

126001914(TMEM106B)

LAV:	100668900(TMEM106B)

TMU:

101358714

ETF:	101661616(TMEM106B)

DNM:	101413491(TMEM106B)

GAS:	123255888(TMEM106B)

SHR:	100934804(TMEM106B)

AFZ:

127539189

PCW:	110217619(TMEM106B)

TVP:	118849634(TMEM106B)

PBRV:

138166005(TMEM106B)

OAA:	100079149(TMEM106B)

TACU:

119940181(TMEM106B)

GGA:	420586(TMEM106B)

PCOC:

116243341(TMEM106B)

MGP:	100543672(TMEM106B)

CJO:	107309113(TMEM106B)

TPAI:

128086600(TMEM106B)

LMUT:

125696504(TMEM106B)

NMEL:

110393850(TMEM106B)

APLA:

101796289(TMEM106B)

ACYG:

106037526(TMEM106B)

CATA:

118247331(TMEM106B)

AFUL:

116485452(TMEM106B)

TGU:	100231230(TMEM106B)

LSR:	110474708(TMEM106B)

SCAN:

103812846(TMEM106B)

PMOA:

120499897(TMEM106B)

OTC:	121343240(TMEM106B)

PRUF:

121352868(TMEM106B)

ATRC:

139591015(TMEM106B)

GFR:	102045220(TMEM106B)

FAB:	101807067(TMEM106B)

OMA:	130249090(TMEM106B)

PHI:	102104810(TMEM106B)

PMAJ:

107200526(TMEM106B)

CCAE:

111924263(TMEM106B)

CCW:	104689141(TMEM106B)

CBRC:

103612312(TMEM106B)

ACOE:

138106388 138106438

ETL:	114054583(TMEM106B)

ZAB:	102074929(TMEM106B)

ZLE:	135443773(TMEM106B)

ACHL:

103806381(TMEM106B)

SVG:	106854518(TMEM106B)

MMEA:

130577046(TMEM106B)

HRT:	120749252(TMEM106B)

SATI:

136360657(TMEM106B)

CCIC:

134053200(TMEM106B)

FPG:	101924813(TMEM106B)

FCH:	102058187(TMEM106B)

CCRI:

104160666(TMEM106B)

NNT:	104411691(TMEM106B)

SHAB:

115609235(TMEM106B)

ACUN:

113476648(TMEM106B)

TALA:

104369400(TMEM106B)

ACHC:

115339358(TMEM106B)

HALD:

104312034(TMEM106B)

HLE:	104828046(TMEM106B)

AGEN:

126037739

HHAR:

128147972(TMEM106B)

GCL:

127013291

CSTI:

104550067(TMEM106B)

LDI:	104349024(TMEM106B)

MNB:	103775184(TMEM106B)

DPUB:

104298816(TMEM106B)

PPUS:

135187852(TMEM106B)

AVIT:

104268449(TMEM106B)

BRHI:

104492489(TMEM106B)

EGZ:	104129184(TMEM106B)

NNI:	104009215(TMEM106B)

PCRI:

104025216(TMEM106B)

PCAO:

104041749(TMEM106B)

PADL:

103918714(TMEM106B)

AFOR:

103900368(TMEM106B)

FGA:	104073843(TMEM106B)

GSTE:

104251726(TMEM106B)

CBOY:

140648351(TMEM106B)

CLV:	102083448(TMEM106B)

MUI:	104534498(TMEM106B)

PGUU:

104472403(TMEM106B)

PLET:

104614807(TMEM106B)

EHS:

104504303

CMAC:

104476967(TMEM106B)

CUCA:

104068001(TMEM106B)

TEO:	104377416(TMEM106B)

BREG:

104632451(TMEM106B)

OHA:	104326547(TMEM106B)

ACAR:

104521805(TMEM106B)

CPEA:

104386341(TMEM106B)

CVF:	104295565(TMEM106B)

RTD:	128905352(TMEM106B)

CRID:

134511259(TMEM106B)

AAM:	106483414(TMEM106B)

AROW:

112971938(TMEM106B)

NPD:	112944739(TMEM106B)

TGT:	104580394(TMEM106B)

DNE:	112986024(TMEM106B)

SCAM:

104147902(TMEM106B)

ASN:	102385449(TMEM106B)

AMJ:	102562307(TMEM106B)

CPOO:

109307525(TMEM106B)

GGN:	109291449(TMEM106B)

PSS:	102444348(TMEM106B)

CMY:	102938601(TMEM106B)

CCAY:

125631487(TMEM106B)

DCC:	119850928(TMEM106B)

CPIC:

101949410(TMEM106B)

TST:	117872260(TMEM106B)

CABI:

116833909(TMEM106B)

MRV:	120398264(TMEM106B)

ACS:	100554688(tmem106b)

ASAO:

132778812(TMEM106B)

PVT:	110072895(TMEM106B)

SUND:

121934878(TMEM106B)

PBI:	103062583(TMEM106B)

PMUR:

107283859(TMEM106B)

CTIG:

120308163(TMEM106B)

TSR:	106550306(TMEM106B)

PGUT:

117655173(TMEM106B)

APRI:

131197782(TMEM106B)

PTEX:

113440130(TMEM106B)

NSS:	113418733(TMEM106B)

VKO:	123022798(TMEM106B)

PMUA:

114607081(TMEM106B)

PRAF:

128424069(TMEM106B)

ZVI:	118091899(TMEM106B)

HCG:	128329177(TMEM106B)

GJA:	107116287(TMEM106B)

STOW:

125440758(TMEM106B)

EMC:	129337433(TMEM106B)

XLA:	444763(tmem106b.S) 779125(tmem106b.L)

XTR:	549566(tmem106b)

NPR:	108799242(TMEM106B)

RTEM:

120939864(TMEM106B)

BBUF:

121000680(TMEM106B)

BGAR:

122937999(TMEM106B)

PWL:	138262091(TMEM106B)

MUO:	115460108(TMEM106B)

GSH:	117354114(TMEM106B)

DRE:	393333(tmem106ba) 566699(tmem106bb)

SRX:	107709260 107724356 107730846 107752274

SANH:

107683194 107696205 107702131 107704771

SGH:	107555560 107582242 107584266 107587075

CCAR:

109064541(tmem106ba) 109065705 109077338 109109174(tmem106bb)

CAUA:

113058603 113059027 113091454 113114999 113119589

CGIB:

127935704 127973177 127979450 128028542

PTET:

122323554(tmem106bb) 122359539(tmem106ba)

LROH:

127177664(tmem106ba) 127182297(tmem106bb)

OMC:	131520419(tmem106ba) 131525354(tmem106bb)

PPRM:

120478867(tmem106ba) 120485362(tmem106bb)

RKG:	130084676(tmem106bb) 130104302(tmem106ba)

MAMB:

125248453(tmem106ba) 125274828(tmem106bb)

CIDE:

127495699 127501478

CERY:

137005007(tmem106ba) 137037310(tmem106bb)

MASI:

127421143 127422369 127425179 127430115

TROS:

130564739(tmem106ba) 130567442(tmem106bb)

TDW:	130428638(tmem106ba)

MANU:

129438302(tmem106ba) 129455370(tmem106bb)

PDAB:

135770874(tmem106ba) 135780022 135785330(tmem106bb)

IPU:	100528568(tmem106bb) 108278007(tmem106ba)

IFU:	128600284(tmem106bb) 128621626(tmem106ba)

PHYP:

113536328 113539218(tmem106b)

SMEO:

124376427(tmem106bb) 124395040(tmem106ba)

TFD:	113643739(tmem106ba) 113661509(tmem106bb)

TVC:	132858237(tmem106ba) 132864265(tmem106bb)

CGAR:

128519442(tmem106bb) 128533702(tmem106ba)

NGRA:

132900637(tmem106bb) 132901686(tmem106ba)

TRN:	134332707(tmem106bb) 134334223(tmem106ba)

AMEX:

103025712(tmem106ba) 103043314(tmem106bb)

CMAO:

118803520(tmem106ba) 118805506(tmem106bb)

EEE:

113587123

SPIL:

134073205(tmem106bb)

TRU:	101074539 115246523

TFS:	130518015(tmem106bb)

TNG:	GSTEN00008793G001

LCO:	109138688(tmem106b)

NCC:	104968068(tmem106b)

TBEN:

117468517(tmem106ba) 117474115

CGOB:

115004641 115020908(tmem106b)

PGEO:

117443255 117460401(tmem106ba)

GACU:

117535416 117543183(tmem106ba)

EMAC:

134861757(tmem106ba) 134874891

ELY:	117263421 117265701(tmem106ba)

EFO:	125893942(tmem106ba) 125904524(tmem106bb)

PLEP:

121945663(tmem106ba) 121958000(tmem106bb)

SLUC:

116035990(tmem106ba)

ECRA:

117945848(tmem106ba)

ESP:	116690830(tmem106b)

PFLV:

114556993(tmem106b)

GAT:	120810122(tmem106ba) 120826382(tmem106bb)

PPUG:

119198083(tmem106ba) 119218812

AFB:	129097156(tmem106bb) 129109182(tmem106ba)

CLUM:

117739148(tmem106bb) 117745548(tmem106ba)

PSWI:

130212707(tmem106ba)

CANA:

137780857(tmem106ba)

CVE:	137872531(tmem106bb) 137891115(tmem106ba)

MSAM:

119897067(tmem106ba) 119907091

SCHU:

122881674(tmem106ba)

CUD:	121513349(tmem106ba) 121523896(tmem106bb)

SPUL:

138583981(tmem106ba) 138609516

LMIX:

132983520(tmem106ba) 132991259(tmem106bb)

ALAT:

119006080(tmem106ba) 119017032

ASTR:

137601528(tmem106ba) 137607165

MZE:	101473054(tmem106b)

ONL:	100700572(tmem106b)

OAU:	116334990(tmem106ba)

OLA:	101159132(tmem106b)

OML:	112136710(tmem106ba)

CSAI:

133441159(tmem106ba)

XMA:	102232554 102234349

XCO:	114142147 114156398

XHE:	116717591 116731713

PRET:

103471929 103477692

PFOR:

103142798 103152865

PLAI:

106940669 106958876(tmem106b)

PMEI:

106931466 106932555

GAF:	122831789 122843961

PPRL:

129352799 129370867

CVG:	107096163(tmem106b) 107101286

CTUL:

119779788(tmem106ba) 119784042

GMU:	124866201(tmem106ba)

NFU:	107379187(tmem106b)

KMR:	108243304(tmem106ba)

ALIM:

106524951(tmem106b)

NWH:	119409796(tmem106ba)

AOCE:

111566260(tmem106ba) 111580949

EJA:	138193713(tmem106ba)

BFRE:

138634079(tmem106ba)

MCEP:

125015882(tmem106ba) 125019630(tmem106bb)

CSEM:

103388985(tmem106b) 103394691

POV:	109631877 109639760

SSEN:

122774322(tmem106ba) 122786742(tmem106bb)

SSOE:

131447258 131471998(tmem106ba)

HHIP:

117770432(tmem106bb) 117777035(tmem106ba)

HSP:	118113540(tmem106ba) 118124524

PPLT:

128449778(tmem106ba) 128461658(tmem106bb)

SMAU:

118284935(tmem106ba) 118292138(tmem106bb)

LCF:	108883219(tmem106ba) 108896356(tmem106bb)

SDU:	111222458(tmem106b)

SLAL:

111644532(tmem106b)

XGL:	120783656(tmem106ba) 120786230(tmem106bb)

HCQ:	109507711 109521114

SSCV:

125974834(tmem106ba) 125986687

SBIA:

133501378(tmem106ba)

PEE:	133396156 133401608(tmem106ba)

PTAO:

133480134(tmem106ba)

BPEC:

110161240(tmem106b)

ENY:	140361598(tmem106bb)

MALB:

109952035 109968969(tmem106b)

BSPL:

114843482(tmem106ba)

SJO:	128366668(tmem106ba) 128373637(tmem106bb)

SSCO:

133983506(tmem106ba) 133996611(tmem106bb)

GMH:	115535237(tmem106b) 115545634

SASA:

106570314 106582194 106588715 106605200(tmem106b)

STRU:

115173805 115175660 115176981 115177917

OTW:	112223019 112229602 112230015 112264533

OMY:	110488129 110488146 110496445 110515888

OGO:	123997669 124006148 124013308 124043337

ONE:	115104786 115121508 115131416 115141134

OKI:	109902087 109903472 109907361 109909121

OKE:	118364372 118367426 118398018 118399518

OMM:	135520187 135522314 135549767 135552017

OCLA:

139365871 139373609 139391668 139392982

SALP:

111955044 111955936 111958907 112067733

SNH:	120022670 120027000 120031196 120048370

CCLU:

121560541 121560984 121571901 121586576

ELS:	105012384 105021891(tmem106b)

OEP:	134023317(tmem106ba) 134040747(tmem106bb)

SFM:	108927353 108935609

PKI:	111839061(tmem106b) 111842799

AANG:

118211019 118233238

AROT:

135262269 135262600(tmem106ba)

CCOG:

133132646(tmem106ba) 133137807

LOC:	102692147(tmem106b)

PSPA:

121313579 121315055

ARUT:

117399673 117435327

PSEX:

120515560(tmem106ba)

LCM:	102358529(TMEM106B)

CMK:	103172406 103182647(tmem106ba)

RTP:	109913386(tmem106bb) 109918282(tmem106a)

CPLA:

122539883(tmem106a) 122549802(tmem106ba)

HOC:	132816027(tmem106ba) 132830899(tmem106a)

LERI:

129710291(tmem106a) 129713126(tmem106ba)

PMRN:

116941056 116948689

LRJ:	133344760 133349677

BFO:

BBEL:

CIN:

SCLV:

SPU:	100891221 752954

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

PFLL:

NAI:	NECAME_13814

BMY:	BM_BM12942(Bm12942)

LOA:	LOAG_07844

TSP:	Tsp_01553 Tsp_02056

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

SMM:	Smp_160410.1

SHX:	MS3_00005100

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100209377 100211531

HSY:	130622592 130622694

RES:	135682469 135682540

AQU:

105314855

» show all

Reference

PMID:22511793

Authors

Lang CM, Fellerer K, Schwenk BM, Kuhn PH, Kremmer E, Edbauer D, Capell A, Haass C

Title

Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.

Journal

J Biol Chem 287:19355-65 (2012)
DOI:10.1074/jbc.M112.365098

Sequence

[hsa:54664]

LinkDB

DBGET integrated database retrieval system