KEGG ORTHOLOGY: K25454

ORTHOLOGY: K25454

Entry

K25454                      KO

Symbol

CFC1

Name

cryptic protein

Disease

H00550

Complete transposition of the great arteries

H00632

Heterotaxy

H00918

Double-outlet right ventricle

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09193 Unclassified: signaling and cellular processes
   99995 Signaling proteins
    K25454  CFC1; cryptic protein

Other DBs

GO:

0038100

Genes

HSA:	55997(CFC1) 653275(CFC1B)

PTR:

459608

PPS:	100990759(CFC1B)

GGO:	101137661(CFC1B)

PON:

100436096

NLE:

100600217

HMH:

116462941

MCC:	702829(CFC1)

MCF:	102141168(CFC1)

MTHB:

126932723

MNI:

105464156

CSAB:

103247122(CFC1)

CATY:

105600120(CFC1)

PANU:

101020633

TGE:	112636589(CFC1)

MLEU:

105529669(CFC1)

RRO:

104674398

RBB:	108538889(CFC1)

TFN:

PTEH:

CANG:

CJC:

SBQ:

CIMI:

MMUR:

PCOQ:

OGA:

MMU:	12627(Cfc1)

MCAL:

110294071

MPAH:

110322148

RNO:	501121(Cfc1)

MCOC:

ANU:

CGE:

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

NCAR:

MMMA:

CFA:

CLUD:

VVP:

VLG:

NPO:

AML:	100473670(CFC1)

UMR:	103664258(CFC1)

UAH:	113251018(CFC1)

UAR:	123791752(CFC1)

ELK:

111161980

LLV:	125092707 125095599 125097312

MPUF:

101679361

MLK:

131810560

NVS:

122899203

ORO:	105757479(CFC1)

EJU:

114204140

ZCA:	113915711 118356839 118356844

MLX:

FCA:

PYU:

PVIV:

LRUF:

PTG:

PPAD:

PUC:

AJU:

HHV:

BTA:

BOM:

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

MBEZ:

SSC:	100514804(CFC1B)

CFR:	102515035(CFC1)

CBAI:

105081094

CDK:

105090756

BACU:

103001484

BMUS:

118898229(CFC1)

LVE:

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:

EPZ:

EAI:

MYB:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

HAI:

RFQ:

PALE:

102888128(CFC1B)

PGIG:

120607173

RAY:	107500632(CFC1B)

MJV:	108385186(CFC1B)

TOD:

LAV:

TMU:

DNM:

MDO:	103099228(TDGF1)

SHR:	105749735(TDGF1)

PCW:

110197658

GGA:	395437(CFC1)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ETL:

ZAB:

ACHL:

SVG:

MMEA:

HRT:

FPG:

FCH:

CLV:

EGZ:

NNI:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:	104331399(TDGF1)

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

104280423(TDGF1)

CVF:

RTD:

CUCA:

TEO:

AAM:

TGT:

SCAM:

ASN:

AMJ:	102567604(CFC1B)

CPOO:

109323305

GGN:

109298221

PSS:

102449702

CMY:	102932571 122465762

CCAY:

125636789 125637398(TDGF1)

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:	107125557(TDGF1)

STOW:

125436713

EMC:

129335130

XLA:	100158378(tdgf1.2.L) 733444(tdgf1.2.S)

XTR:	100486054(tdgf1.2)

RTEM:

BGAR:

GSH:

CPLA:

PMRN:

LPIC:

OSN:

Reference

PMID:11062482

Authors

Bamford RN, Roessler E, Burdine RD, Saplakoglu U, dela Cruz J, Splitt M, Goodship JA, Towbin J, Bowers P, Ferrero GB, Marino B, Schier AF, Shen MM, Muenke M, Casey B

Title

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

Journal

Nat Genet 26:365-9 (2000)
DOI:10.1038/81695

Sequence

[hsa:55997]

LinkDB

DBGET integrated database retrieval system