KEGG   ORTHOLOGY: K25562
Entry
K25562                      KO                                     
Symbol
creE
Name
L-aspartate N-monooxygenase (nitrosuccinate-forming) [EC:1.14.13.248]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00951  Cremeomycin biosynthesis, aspartate/3,4-AHBA => cremeomycin
Reaction
R12907  L-aspartate,NADPH:oxygen oxidoreductase [(2S)-2-nitrobutanedioate-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K25562  creE; L-aspartate N-monooxygenase (nitrosuccinate-forming)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.248  L-aspartate N-monooxygenase (nitrosuccinate-forming)
     K25562  creE; L-aspartate N-monooxygenase (nitrosuccinate-forming)
Other DBs
COG: COG4529
Genes
MAW: 19254044(J3458_014278)
MBRN: 26247442(G6M90_00g113260)
PCHM: VFPPC_14825
ELA: UCREL1_1623
AOR: AO090038000030
AFV: AFLA_012285
PCS: N7525_002277
XSK: AB0856_000973
RAGG: QUB73_27990
PHOI: ACLISE_06700
MAB: MAB_0289
MABB: MASS_0291
MCHE: BB28_01430
SALS: SLNWT_1071
SLD: T261_5726
SALU: DC74_2833
SALL: SAZ_15540
SAUH: SU9_009660
STPB: QR97_05360
SMIB: SMIR_27025
SCT: SCAT_5479
AREV: RVR_1684 RVR_4141(fur16)
AMI: Amir_4655
KAL: KALB_2259
SAQ: Sare_1050
AG: ALA99202(creE) BAU09302(creE)
 » show all
Reference
  Authors
Sugai Y, Katsuyama Y, Ohnishi Y.
  Title
A nitrous acid biosynthetic pathway for diazo group formation in bacteria.
  Journal
Nat Chem Biol 12:73-5 (2016)
DOI:10.1038/nchembio.1991
  Sequence
Reference
  Authors
Hagihara R, Katsuyama Y, Sugai Y, Onaka H, Ohnishi Y.
  Title
Novel desferrioxamine derivatives synthesized using the secondary metabolism-specific nitrous acid biosynthetic pathway in Streptomyces davawensis.
  Journal
J Antibiot (Tokyo) 71:911-919 (2018)
DOI:10.1038/s41429-018-0088-1
  Sequence
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