KEGG   ORTHOLOGY: K25581
Entry
K25581                      KO                                     
Symbol
CYP82M3
Name
ecgonone synthase [EC:1.14.14.194]
Pathway
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R13546  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K25581  CYP82M3; ecgonone synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K25581  CYP82M3; ecgonone synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.194  ecgonone synthase
     K25581  CYP82M3; ecgonone synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP82 family
   K25581  CYP82M3; ecgonone synthase
Genes
SLY: 101256720 101264988
SPEN: 107001763 107032483
SOT: 102595151
SSTN: 125864932 125865406
SDUL: 129876576 129877096
CANN: 107854582 107860624
LBB: 132605462 132609369 132636906 132640729
NTA: 107810711(CYP82M1v1) 107822970
NSY: 104246960
NTO: 104108880
NAU: 109235450
PTAB: 142543207
CARB: 140005252 140005253
AG: AYU65303(CYP82M3)
 » show all
Reference
PMID:30538251
  Authors
Bedewitz MA, Jones AD, D'Auria JC, Barry CS.
  Title
Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization.
  Journal
Nat Commun 9:5281 (2018)
DOI:10.1038/s41467-018-07671-3
  Sequence
[ag:AYU65303]
Reference
PMID:37068250
  Authors
Wang YJ, Tain T, Yu JY, Li J, Xu B, Chen J, D'Auria JC, Huang JP, Huang SX.
  Title
Genomic and structural basis for evolution of tropane alkaloid biosynthesis.
  Journal
Proc Natl Acad Sci U S A 120:e2302448120 (2023)
DOI:10.1073/pnas.2302448120
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