KEGG   ORTHOLOGY: K27689
Entry
K27689                      KO                                     
Symbol
hadAB
Name
meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB [EC:4.2.1.-]
Pathway
map00074  Mycolic acid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00885  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA)
Reaction
R13260  long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (long-chain trans-2-enoyl-[acyl-carrier protein]-forming)
R13264  very-long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (very-long-chain trans-2-enoyl-[acyl-carrier protein]-forming)
R13268  ultra-long-chain-mono-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (ultra-long-chain mono-unsaturated trans-2-enoyl-[acyl-carrier protein]-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00074 Mycolic acid biosynthesis
    K27689  hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K27689  hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K27689  hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB
Other DBs
COG: COG2030
Genes
MMAL: CKJ54_00365
MSER: MTY59_19580
MSA: Mycsm_06410
MMI: MMAR_0106
MMAE: MMARE11_00950
MLI: MULP_00089
MPSE: MPSD_00990
MSHO: MSHO_11720
MMC: Mmcs_5324
MKM: Mkms_5413
MJL: Mjls_5703
MYV: G155_29860
MYE: AB431_28790
MDX: BTO20_00965
MSHG: MSG_03656
MFJ: MFLOJ_44970
MSTO: MSTO_49190
MSIM: MSIM_23930
MSAK: MSAS_43080
MKU: I2456_00760
MLW: MJO58_23005
MXE: MYXE_48420
MNV: MNVI_17600
MPAG: C0J29_00515
MNM: MNVM_19590
MGOR: H0P51_00485
MCOO: MCOO_15210
MBAI: MB901379_04018
MSEO: MSEO_39420
MHEK: JMUB5695_04665
MGAU: MGALJ_41840
MBRD: MBRA_15370
MMAM: K3U93_00340
MPAA: MKK62_24395
MMEH: M5I08_24160
MKY: IWGMT90018_01480
MADI: A7U43_03595
MWU: PT015_17975
MYW: BVC93_13235
MYJ: BCA37_29320
MSM: MSMEG_6754
MSG: MSMEI_6572
MSB: LJ00_33370
MSN: LI99_33375
MSH: LI98_33380
MVA: Mvan_5844
MGI: Mflv_0994
MSP: Mspyr1_51960
MCB: Mycch_5231
MNE: D174_01295
MYN: MyAD_01265
MFT: XA26_60360
MPHL: MPHLCCUG_05132
MVQ: MYVA_5786
MLL: B1R94_28200
MRH: MycrhN_1733
MTHN: 4412656_04651
MHAS: MHAS_04312(phaJ_2)
MDU: MDUV_43980
MCHT: MCHIJ_13270
MDR: MDOR_37240
MAUU: NCTC10437_05651
MMAG: MMAD_02770
MMOR: MMOR_06270
MFX: MFAL_09940
MAIC: MAIC_00580
MIJ: MINS_28960
MALV: MALV_36480
MTY: MTOK_14440
MPSC: MPSYJ_10020
MARZ: MARA_37900
MGAD: MGAD_43350
MHEV: MHEL_22950
MSAR: MSAR_14790
MANY: MANY_40380
MAUB: MAUB_32440
MPOF: MPOR_04520
MPHU: MPHO_37600
MMUC: C1S78_029025
MMAT: MMAGJ_25670
MBOK: MBOE_11570
MFG: K6L26_01765
MSEI: MSEDJ_10160
MFLV: NCTC10271_05090
MCEE: MCEL_31440
MBRM: L2Z93_001894
MMON: EWR22_28630
MGO: AFA91_05765
MHOL: K3U96_00665
MSEN: K3U95_28620
MPAE: K0O64_28965
MRF: MJO55_27090
MDF: K0O62_00760
MCRO: MI149_28750
MGRO: FZ046_07210
MAUS: JN090_29290
MFRE: EXE63_15475
MBUG: MU0053_004956
MKR: MKOR_09120
MPAK: MIU77_08975
MAB: MAB_4780
MMV: MYCMA_02975
MABB: MASS_4852
MABL: MMASJCM_4839
MCHE: BB28_24340
MIZ: BAB75_27065
MSTE: MSTE_04931
MSAO: MYCSP_22275
MSAL: DSM43276_04606
MJD: JDM601_4227
MTER: 4434518_04167
MMIN: MMIN_16550
MHIB: MHIB_35270
MHER: K3U94_23000
MVM: MJO54_23060
MKK: MU0083_003858
NFA: NFA_51180
NFR: ERS450000_04773
NCY: NOCYR_2781 NOCYR_4906
NBR: O3I_014345 O3I_024025 O3I_038520
NNO: NONO_c69560 NONO_c72980
NSL: BOX37_12080 BOX37_29300
NSR: NS506_00060(phaJ)
NTP: CRH09_36620
NOZ: DMB37_17285 DMB37_38885
NOD: FOH10_00310(hadB)
NAH: F5544_41000(hadB)
NAD: NCTC11293_00027 NCTC11293_03986
NWL: NWFMUON74_65160
NIE: KV110_37685(hadB)
NTC: KHQ06_09460(hadB) KHQ06_25600
NHU: H0264_08745(hadB) H0264_25240
NYA: LTV02_10420 LTV02_24310
NGP: LTT66_08445
NSPU: IFM12276_56810
NYU: D7D52_06680(hadB) D7D52_30400
NVU: V7968_03695 V7968_22080 V7968_27645 V7968_31945
RHB: NY08_3148
RHU: A3Q40_01427
RHOP: D8W71_06140(hadB)
RFA: A3L23_01345
RHS: A3Q41_02009
WHR: OG579_08195
GBR: Gbro_0464 Gbro_1106
GPO: GPOL_c06820 GPOL_c11830
GOR: KTR9_0970 KTR9_2676
GOQ: ACH46_16615
GTA: BCM27_05915 BCM27_14185
GOC: CXX93_18855
GIT: C6V83_11905 C6V83_16775
GRU: GCWB2_05220 GCWB2_10540
GOM: D7316_03992 D7316_04775(phaJ)
GAV: C5O27_17010 C5O27_22110
GOD: GKZ92_04950 GKZ92_10240
GOS: QAD21_05070 QAD21_13985
GOJ: GR168_05145 GR168_13425
GAM: GII34_04410
GPD: GII33_18475
GJI: H1R19_04955 H1R19_13430
GOI: LK459_06980 LK459_14835
GHN: MVF96_05310 MVF96_13925
GAMI: IHQ52_08260 IHQ52_13480
GMG: NWF22_04255
GSI: P5P27_01850
GOO: HUN08_02760 HUN08_15050
GOP: ACE11G_14950 ACE11G_16690
SPIN: KV203_03405(hadB) KV203_07150
BFY: ABYF36_05745
 » show all
Reference
PMID:17804795
  Authors
Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffe M, Backbro K, Quemard A
  Title
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.
  Journal
Proc Natl Acad Sci U S A 104:14628-33 (2007)
DOI:10.1073/pnas.0704132104
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