KEGG   ORTHOLOGY: K27782
Entry
K27782                      KO                                     
Symbol
NO
Name
norfluorocurarine 18-hydroxylase [EC:1.14.14.188]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00980  Strychnine biosynthesis, geissoschizine => strychnine
Reaction
R13332  (19E)-cura-2(16),19-dien-17-al,[NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K27782  NO; norfluorocurarine 18-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.188  norfluorocurarine 18-hydroxylase
     K27782  NO; norfluorocurarine 18-hydroxylase
Genes
AG: UQZ09624(NO) UQZ09633(NO)
Reference
PMID:35794473
  Authors
Hong B, Grzech D, Caputi L, Sonawane P, Lopez CER, Kamileen MO, Hernandez Lozada NJ, Grabe V, O'Connor SE
  Title
Biosynthesis of strychnine.
  Journal
Nature 607:617-622 (2022)
DOI:10.1038/s41586-022-04950-4
  Sequence
[ag:UQZ09624 UQZ09633]
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