KEGG   ORTHOLOGY: K27790
Entry
K27790                      KO                                     
Symbol
REDOX2
Name
17-dehydrostemmadenine reductase [EC:1.1.1.439]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00965  Vinblastine biosynthesis, geissoschizine => vinblastine
Reaction
R13349  stemmadenine:NADP+ 17-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K27790  REDOX2; 17-dehydrostemmadenine reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.439  17-dehydrostemmadenine reductase
     K27790  REDOX2; 17-dehydrostemmadenine reductase
Genes
AG: AVM85918(REDOX2)
Reference
  Authors
Qu Y, Easson MEAM, Simionescu R, Hajicek J, Thamm AMK, Salim V, De Luca V
  Title
Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizine.
  Journal
Proc Natl Acad Sci U S A 115:3180-3185 (2018)
DOI:10.1073/pnas.1719979115
  Sequence
LinkDB

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