KEGG   ORTHOLOGY: K28008
Entry
K28008                      KO                                     
Symbol
hcgC
Name
FeGP 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase [EC:2.1.1.400]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K28008  hcgC; FeGP 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.400  6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase
     K28008  hcgC; FeGP 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase
Other DBs
COG: COG4017
Genes
MJA: MJ_0489
MFE: Mefer_0723
MVU: Metvu_0360
MFS: MFS40622_1760
MIF: Metin_0135
MJH: JH146_1405
MESG: MLAUSG7_0417
MESA: MLASG1_1596
MIG: Metig_1363
MMP: MMP1498
MMQ: MmarC5_0079
MMX: MmarC6_1176
MMZ: MmarC7_0742
MMD: GYY_08330
MMAK: MMKA1_17220
MMAO: MMOS7_16040
MMAD: MMJJ_13400
MAE: Maeo_1290
MVN: Mevan_0807
MVO: Mvol_1087
MOK: Metok_1034
METF: CFE53_03300
MTH: MTH_1145
MMG: MTBMA_c15290(hcgC)
MWO: MWSIV6_1537
MTEE: MTTB_02770
METC: MTCT_1038
METE: tca_01102
METZ: METMT2_1153
METK: FVF72_05860
MTHM: FZP57_07360
METJ: FZP68_03315
MSI: Msm_0575
MEB: Abm4_0010(hgcC)
MMIL: sm9_0394(hcgC)
MEYE: TL18_01635
MOL: YLM1_0196
METV: K4897_03445
METT: CIT01_01050
MEME: HYG87_04880
MFV: Mfer_0770
MKA: MK0014
MLA: Mlab_1740
MPI: Mpet_1997
MFO: Metfor_0860
 » show all
Reference
PMID:36264001
  Authors
Arriaza-Gallardo FJ, Schaupp S, Zheng YC, Abdul-Halim MF, Pan HJ, Kahnt J, Angelidou G, Paczia N, Hu X, Costa K, Shima S
  Title
The Function of Two Radical-SAM Enzymes, HcgA and HcgG, in the Biosynthesis of the [Fe]-Hydrogenase Cofactor.
  Journal
Angew Chem Int Ed Engl 61:e202213239 (2022)
DOI:10.1002/anie.202213239
  Sequence
[mmp:MMP1498]
Reference
PMID:37671838
  Authors
Arriaza-Gallardo FJ, Zheng YC, Gehl M, Nomura S, Fernandes-Queiroz JP, Shima S
  Title
[Fe]-Hydrogenase, Cofactor Biosynthesis and Engineering.
  Journal
Chembiochem 24:e202300330 (2023)
DOI:10.1002/cbic.202300330
Reference
PMID:27391308
  Authors
Fujishiro T, Bai L, Xu T, Xie X, Schick M, Kahnt J, Rother M, Hu X, Ermler U, Shima S.
  Title
Identification of HcgC as a SAM-Dependent Pyridinol Methyltransferase in [Fe]-Hydrogenase Cofactor Biosynthesis.
  Journal
Angew Chem Int Ed Engl 55:9648-51 (2016)
DOI:10.1002/anie.201604352
  Sequence
[mmp:MMP1498]
Reference
PMID:35286742
  Authors
Schaupp S, Arriaza-Gallardo FJ, Pan HJ, Kahnt J, Angelidou G, Paczia N, Costa K, Hu X, Shima S.
  Title
In Vitro Biosynthesis of the [Fe]-Hydrogenase Cofactor Verifies the Proposed Biosynthetic Precursors.
  Journal
Angew Chem Int Ed Engl 61:e202200994 (2022)
DOI:10.1002/anie.202200994
  Sequence
[mmp:MMP1498]
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