KEGG ORTHOLOGY: K28056

ORTHOLOGY: K28056

Entry

K28056                      KO

Symbol

RHPN2

Name

rhophilin-2

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K28056  RHPN2; rhophilin-2
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Others
   Others
    K28056  RHPN2; rhophilin-2

Genes

HSA:	85415(RHPN2)

PTR:	107968458 112205630 749937(RHPN2)

PPS:	100985314(RHPN2) 117975754 117977952

GGO:	101128715(RHPN2) 101152972 129527053

PON:	100437364(RHPN2)

PPYG:

129020408(RHPN2)

NLE:	100584105(RHPN2)

HMH:	116478849(RHPN2)

SSYN:

129459863(RHPN2)

MCC:	716602(RHPN2)

MCF:	102130444(RHPN2)

MTHB:

126943369

MNI:	105495654(RHPN2)

CSAB:

103234453(RHPN2)

CATY:

105578120(RHPN2)

PANU:

101009983(RHPN2)

TGE:	112613442(RHPN2)

MLEU:

105550345(RHPN2)

RRO:	104665242(RHPN2)

RBB:	108517245(RHPN2)

TFN:	117092285(RHPN2)

PTEH:

111553940(RHPN2)

CANG:

105515507(RHPN2)

CJC:	100408738(RHPN2)

SBQ:	101032673(RHPN2)

CIMI:

108286411(RHPN2)

ANAN:

105714519(RHPN2)

CSYR:

103258959(RHPN2)

MMUR:

105876985(RHPN2)

LCAT:

123624140(RHPN2)

PCOQ:

105812558(RHPN2)

OGA:	100953186(RHPN2)

MMU:	52428(Rhpn2)

MCAL:

110298173(Rhpn2)

MPAH:

110333840(Rhpn2)

RNO:	308516(Rhpn2)

MCOC:

116102031(Rhpn2)

ANU:	117694634(Rhpn2)

ASYL:

127670896(Rhpn2)

MUN:	110551418(Rhpn2)

CGE:	100757315(Rhpn2)

MAUA:

101825600(Rhpn2)

PROB:

127218050 127238631(Rhpn2)

PLEU:

114698906(Rhpn2)

MORG:

121449711(Rhpn2)

MFOT:

126486636

AAMP:

119821077(Rhpn2)

NGI:	103739156(Rhpn2)

HGL:	101722256(Rhpn2)

CPOC:

100723999(Rhpn2)

CCAN:

109698094(Rhpn2)

DORD:

105993028(Rhpn2)

DSP:	122097599(Rhpn2)

PLOP:

125367994(Rhpn2)

NCAR:

124967610

MMMA:

107151692(Rhpn2)

ITI:	101968347(Rhpn2)

OCU:

100357570

OPI:	101522902(RHPN2)

TUP:	102495302(RHPN2)

GVR:	103601145(RHPN2)

CFA:	403518(RHPN2)

CLUD:

112645579(RHPN2)

VVP:	112928448(RHPN2)

VLG:	121485346(RHPN2)

NPO:	129500565(RHPN2)

AML:	100484053(RHPN2)

UMR:	103661347(RHPN2)

UAH:	113244725(RHPN2)

UAR:	123791389(RHPN2)

ELK:

111161435

LLV:

125089269

MPUF:

101670771(RHPN2)

MNP:	132006147(RHPN2)

MLK:	131817938(RHPN2)

NVS:	122911510(RHPN2)

ORO:	101367174(RHPN2)

EJU:	114224449(RHPN2)

ZCA:	113936477(RHPN2)

MLX:	118022734(RHPN2)

NSU:	110590273(RHPN2)

LWW:	102745782(RHPN2)

FCA:	101091576(RHPN2)

PYU:	121011627(RHPN2)

PCOO:

112851066(RHPN2)

PBG:	122494144(RHPN2)

PVIV:

125152789(RHPN2)

LRUF:

124511265

LGF:	123579050(RHPN2)

AJU:

106975775

PTG:	102956444(RHPN2)

PPAD:

109251594(RHPN2)

PUC:

125915960

PLEZ:

122207681(RHPN2)

HHV:	120231709(RHPN2)

BTA:	533687(RHPN2)

BOM:	102287330(RHPN2)

BIU:	109572822(RHPN2)

BBUB:

102412489(RHPN2)

BBIS:

104995202(RHPN2)

CHX:	102189513(RHPN2)

OAS:	101117270(RHPN2)

BTAX:

128063902(RHPN2)

CSUM:

138096162(RHPN2)

ODA:	120860735 120872648(RHPN2)

CCAD:

122421560(RHPN2)

MREE:

136161166(RHPN2)

OVR:	110140698(RHPN2) 139032209

MBEZ:

129546903(RHPN2)

SSC:	100620673(RHPN2)

CFR:	102503938(RHPN2)

CBAI:

105064995(RHPN2)

CDK:	105096711(RHPN2)

VPC:	102524965(RHPN2)

BACU:

103018141(RHPN2)

BMUS:

118885550(RHPN2)

LVE:	103082832(RHPN2)

OOR:	101271820(RHPN2)

LALB:

132509598(RHPN2)

DLE:	111180937(RHPN2)

PCAD:

102975097(RHPN2)

PSIU:

116744479(RHPN2)

NASI:

112392411(RHPN2)

ECB:	100056200(RHPN2)

EPZ:	103547063(RHPN2)

EAI:	106830602(RHPN2)

MYB:	102240394(RHPN2)

MYD:	102756200(RHPN2)

MMYO:

118674465(RHPN2)

MLF:	102418374(RHPN2)

MDT:	132215597 132217058

MYUM:

138996907(RHPN2)

PKL:	118720559(RHPN2)

EFUS:

103284471(RHPN2)

MNA:	107543387(RHPN2)

DRO:	112320121(RHPN2)

SHON:

118976306(RHPN2)

AJM:	119044677(RHPN2)

PDIC:

114510915(RHPN2)

PHAS:

123823754(RHPN2)

MMF:	118639467(RHPN2)

PPAM:

129083165(RHPN2)

HAI:	109389199(RHPN2)

RFQ:	117035154(RHPN2)

PALE:

102892164(RHPN2)

PGIG:

120622787(RHPN2)

PVP:	105299896(RHPN2)

RAY:	107504197(RHPN2)

MJV:	108384625(RHPN2)

TOD:	119249211(RHPN2)

SARA:

101558287(RHPN2)

SFUM:

130043783(RHPN2)

SETR:

126027593(RHPN2)

LAV:	100657172(RHPN2)

TMU:

101345856

ETF:	101649718(RHPN2)

DNM:	101441161(RHPN2)

MDO:	100012878(RHPN2)

GAS:	123237332(RHPN2)

SHR:	100915549(RHPN2)

AFZ:

127550640

PCW:	110207408(RHPN2)

TVP:	118841534(RHPN2)

PBRV:

138157130(RHPN2)

OAA:	100077978(RHPN2)

TACU:

119934365(RHPN2)

GGA:	415771(RHPN2)

PCOC:

116244012(RHPN2)

CJO:	107319249(RHPN2)

TPAI:

128082679(RHPN2)

LMUT:

125699453(RHPN2)

NMEL:

110404287(RHPN2)

APLA:

101802559(RHPN2)

ACYG:

106033153(RHPN2)

CATA:

118246281(RHPN2)

AFUL:

116493817(RHPN2)

TGU:	100229146(RHPN2)

LSR:	110484127(RHPN2)

SCAN:

103821150(RHPN2)

PMOA:

120504470(RHPN2)

OTC:	121331636(RHPN2)

PRUF:

121365933(RHPN2)

ATRC:

139596202(RHPN2)

GFR:	102041538(RHPN2)

FAB:	101811269(RHPN2)

OMA:	130257668(RHPN2)

PHI:	102104785(RHPN2)

PMAJ:

107209775(RHPN2)

CCAE:

111934694(RHPN2)

CCW:	104687381(RHPN2)

CBRC:

103617090(RHPN2)

ACOE:

138117214(RHPN2)

ETL:	114065356(RHPN2)

ZAB:	102069372(RHPN2)

ZLE:	135452596(RHPN2)

ACHL:

103805577(RHPN2)

SVG:	106856562(RHPN2)

MMEA:

130585650(RHPN2)

HRT:	120757622(RHPN2)

SATI:

136366702(RHPN2)

CCIC:

134048344(RHPN2)

FPG:	101924585(RHPN2)

FCH:	102055841(RHPN2)

CCRI:

104169073(RHPN2)

NNT:	104408384(RHPN2)

SHAB:

115619776(RHPN2)

ACUN:

113484360(RHPN2)

TALA:

104359240(RHPN2)

ACHC:

115346357(RHPN2)

HALD:

104320803(RHPN2)

HLE:	104842624(RHPN2)

AGEN:

126040381

HHAR:

128146100(RHPN2)

GCL:

127021335

CSTI:

104550441(RHPN2)

LDI:	104350042(RHPN2)

MNB:	103781353(RHPN2)

DPUB:

104302269(RHPN2)

PPUS:

135184267(RHPN2)

AVIT:

104271077(RHPN2)

BRHI:

104488989(RHPN2)

EGZ:	104123649(RHPN2)

NNI:	104013301(RHPN2)

PCRI:

104031032

PCAO:

104040027(RHPN2)

PADL:

103913780(RHPN2)

AFOR:

103895627(RHPN2)

FGA:	104083530(RHPN2)

GSTE:

104264602(RHPN2)

CBOY:

140656435(RHPN2)

CLV:	102083460(RHPN2)

MUI:	104546802(RHPN2)

PGUU:

104458510(RHPN2)

PLET:

104614375(RHPN2)

EHS:	104503619(RHPN2)

CMAC:

104474448(RHPN2)

CUCA:

104065471(RHPN2)

TEO:	104381128(RHPN2)

BREG:

104629849(RHPN2)

OHA:	104339213(RHPN2)

ACAR:

104521816(RHPN2)

CPEA:

104396384(RHPN2)

CVF:	104283258(RHPN2)

RTD:	128908441(RHPN2)

CRID:

134515502(RHPN2)

AAM:	106483303(RHPN2)

AROW:

112963045(RHPN2)

NPD:	112949853(RHPN2)

TGT:	104569343(RHPN2)

DNE:	112987629(RHPN2)

SCAM:

104146371(RHPN2)

ASN:	102383998(RHPN2)

AMJ:	106736795(RHPN2)

CPOO:

109310591(RHPN2)

GGN:	109289532(RHPN2)

PSS:	102446975(RHPN2)

CMY:	102939055(RHPN2)

CCAY:

125645360(RHPN2)

DCC:	119841095(RHPN2)

CPIC:

101949901(RHPN2)

TST:	117886678(RHPN2)

CABI:

116820703(RHPN2)

MRV:	120384579(RHPN2)

ACS:	100559812(rhpn2)

ASAO:

132783026(RHPN2)

PVT:	110089520(RHPN2)

SUND:

121914557(RHPN2)

PBI:	103066670(RHPN2)

PMUR:

107292577(RHPN2)

CTIG:

120300911(RHPN2)

TSR:	106550755(RHPN2)

PGUT:

117670533(RHPN2)

APRI:

131184399(RHPN2)

PTEX:

113448314 113448385(RHPN2)

NSS:	113417503(RHPN2)

VKO:	123022345(RHPN2)

PMUA:

114602307(RHPN2)

PRAF:

128419525(RHPN2)

ZVI:	118086391(RHPN2)

HCG:	128334577(RHPN2)

GJA:	107108319(RHPN2)

STOW:

125443629(RHPN2)

EMC:	129343918(RHPN2)

XLA:	444802(rhpn2.S) 494748(rhpn2.L)

XTR:	100145690(rhpn2)

NPR:	108798936(RHPN2)

RTEM:

120917871(RHPN2)

BBUF:

120981066(RHPN2)

BGAR:

122920314(RHPN2)

PWL:	138267530(RHPN2)

MUO:	115470845(RHPN2)

GSH:	117359924(RHPN2)

DRE:	321330(rhpn2)

SRX:	107722367 107741034

SANH:

107657133 107696719

SGH:	107551478(rhpn2) 107554616

CCAR:

109093207(rhpn2) 109094245

CAUA:

113051433 113106074(rhpn2)

CGIB:

127962317 128016835

PTET:

122349066(rhpn2)

LROH:

127168610(rhpn2)

OMC:	131543657(rhpn2)

PPRM:

120468869(rhpn2)

RKG:	130069729(rhpn2)

MAMB:

125265045(rhpn2)

CIDE:

127516110

CERY:

137030396(rhpn2)

MASI:

127415192 127432780

TROS:

130557871(rhpn2)

TDW:	130425675(rhpn2)

MANU:

129444992(rhpn2)

PDAB:

135778879(rhpn2)

IPU:

108259318

IFU:	128602868(rhpn2)

PHYP:

113546754(rhpn2)

SMEO:

124379893(rhpn2)

TFD:	113634248(rhpn2)

TVC:	132838611(rhpn2)

CGAR:

128519318(rhpn2)

NGRA:

132875279(rhpn2)

TRN:	134303975(rhpn2)

AMEX:

103031065(rhpn2)

CMAO:

118817433(rhpn2)

EEE:	113576727(rhpn2)

CHAR:

105901335(rhpn2)

SPIL:

134068779(rhpn2)

TRU:	101077188(rhpn2)

TFS:	130517153(rhpn2)

TNG:	GSTEN00022359G001

LCO:	104919805(rhpn2)

NCC:	104954203(rhpn2)

TBEN:

117484261(rhpn2)

CGOB:

115006376(rhpn2)

PGEO:

117468340(rhpn2)

GACU:

117536429(rhpn2)

EMAC:

134863139(rhpn2)

ELY:	117256815(rhpn2)

EFO:	125904729(rhpn2)

PLEP:

121941446(rhpn2)

SLUC:

116056847(rhpn2)

ECRA:

117944451(rhpn2)

ESP:

116693015

PFLV:

114570429(rhpn2)

GAT:	120831458(rhpn2)

PPUG:

119225611(rhpn2)

AFB:	129102707(rhpn2)

CLUM:

117750648(rhpn2)

PSWI:

130192767(rhpn2)

CANA:

137801975(rhpn2)

CVE:	137887948(rhpn2)

MSAM:

119889866(rhpn2)

SCHU:

122881922(rhpn2)

CUD:	121514697(rhpn2)

SPUL:

138590181(rhpn2)

LMIX:

132977645(rhpn2)

ALAT:

119018498(rhpn2)

ASTR:

137599171(rhpn2)

MZE:	101480823(rhpn2)

ONL:	100710631(rhpn2)

OAU:	116325573(rhpn2)

OLA:	101173292(rhpn2)

OML:	112160603(rhpn2)

CSAI:

133421735(rhpn2)

XMA:	102218537(rhpn2)

XCO:	114142558(rhpn2)

XHE:	116718819(rhpn2)

PRET:

103462213(rhpn2)

PFOR:

103131489(rhpn2)

PLAI:

106961617(rhpn2)

PMEI:

106915838(rhpn2)

GAF:	122824970(rhpn2)

PPRL:

129379333(rhpn2)

CVG:	107085061(rhpn2)

CTUL:

119773824(rhpn2)

GMU:	124867088(rhpn2)

NFU:	107381986(rhpn2)

KMR:	108241604(rhpn2)

ALIM:

106524255(rhpn2)

NWH:	119430180(rhpn2)

AOCE:

111563334(rhpn2)

EJA:	138213245(rhpn2)

BFRE:

138616172(rhpn2)

CSEM:

103379233(rhpn2)

POV:	109625172(rhpn2)

SSEN:

122772472(rhpn2)

SSOE:

131459276(rhpn2)

HHIP:

117753127(rhpn2)

HSP:	118111380(rhpn2)

PPLT:

128437334(rhpn2)

SMAU:

118302483(rhpn2)

LCF:

108897728

SDU:	111222165(rhpn2)

SLAL:

111672355(rhpn2)

XGL:	120788933(rhpn2)

HCQ:	109519701(rhpn2)

SSCV:

125966689(rhpn2)

SBIA:

133498252(rhpn2)

PEE:	133398738(rhpn2)

PTAO:

133473565(rhpn2)

BPEC:

110175270(rhpn2)

ENY:	140380979(rhpn2)

MALB:

109969916(rhpn2)

BSPL:

114852550(rhpn2)

SJO:	128358415(rhpn2)

SSCO:

133978088(rhpn2)

GMH:	115558497(rhpn2)

SASA:

106588072(rhpn2)

STRU:

115202554 115203701

OTW:	112242344 121845719

OMY:	110518216(rhpn2) 118944442

OGO:

124021160

OKI:	109885826 116363055

OKE:

127922599

OMM:	135554779 135554798

OCLA:

139384794 139411747

CCLU:

121560585

ELS:	105006299(rhpn2)

OEP:	134027869(rhpn2)

SFM:	108926207 108941153(rhpn2)

PKI:	111861209(rhpn2)

AANG:

118215487(rhpn2)

AROT:

135241796(rhpn2)

CCOG:

133111520(rhpn2)

LOC:	102690911(rhpn2)

PSPA:

121296596 121325583

ARUT:

117424170 117425756(rhpn2)

PSEX:

120535654(rhpn2)

LCM:	102347821(RHPN2)

CMK:	103188077(rhpn2)

RTP:	109924296(rhpn2)

CPLA:

122558184(rhpn2)

HOC:	132823848(rhpn2)

DME:	Dmel_CG8497(Rhp)

DER:

6550673

DSE:

6619981

DSI:	Dsimw501_GD17246(Dsim_GD17246)

DYA:	Dyak_GE17224

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI15742

DAZ:

108618184

DNV:

108656530

DHE:

111600212

DVI:	6632150(Rhp)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119670714 119672071

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135957665(Rhp)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ010630

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139105747(Rhp)

TLN:	139808720(Rhp)

HST:

DQU:

CFO:

FEX:

PMEC:

138940265(Rhp)

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124215381(Rhp)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138123208(Rhp)

DPA:

109543868

ESIM:

136419863(Rhp)

EFOR:

136341364(Rhp)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

135799502(Rhp)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213344

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137925449(Rhp)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM204130

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138703529(Rhp)

SGRE:

126277966

BROR:

134527958

IEL:

124155336

HAMR:

139689946 139694440(Rhp)

FCD:

110863422

DPX:	DAPPUDRAFT_43798

DMK:

116920210

DPZ:

124336912

AFRA:

136033194 136033196

PVM:	113829496(Rhp)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123769625(Rhp)

CQD:	128700002(Rhp)

PTRU:

ESN:

MNZ:

MRJ:

PORN:

139758150(Rhp)

HAZT:

EAF:

LSM:

TCF:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

CVS:	136989896(Rhp)

PTEP:

107439462 107441903

ABRU:

129984002 129985208

UDV:	129224146 129232073

SDM:	118184184 118201206

LPOL:

106459865 106463073

PMEO:

129590215

TSP:

Tsp_05621

LGI:	LOTGIDRAFT_155816

PVUL:

PCAN:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LAK:	106160901 106174034

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

AQU:

Reference

PMID:12473120

Authors

Mircescu H, Steuve S, Savonet V, Degraef C, Mellor H, Dumont JE, Maenhaut C, Pirson I

Title

Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP.

Journal

Eur J Biochem 269:6241-9 (2002)
DOI:10.1046/j.1432-1033.2002.03343.x

Sequence

[hsa:85415]

LinkDB

DBGET integrated database retrieval system