KEGG ORTHOLOGY: K28227

ORTHOLOGY: K28227

Entry

K28227                      KO

Symbol

scdY, echA20

Name

HIEC-CoA hydrolase [EC:4.1.-.-]

Pathway

map00984

Steroid degradation

map01120

Microbial metabolism in diverse environments

Reaction

R13481

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K28227  scdY, echA20; HIEC-CoA hydrolase

Other DBs

COG:

COG1024

Genes

RGL:	CS053_01825

VAF:	D1115_22685

PRE:	PCA10_13430

PFUW:

PLAL:

PPUT:

PPUN:

PPUU:

PKC:

PFZ:	AV641_09535

PLQ:	AA042_00490

PPSY:

AOC04_06360

PSET:

THL1_1415

PSIL:

PMA3_11825

PKE:	DLD99_14620

PUM:	HGP31_20675

PPSH:

G5J76_12675

PAZE:

KSS91_19135

PTAE:

NCTC10697_01825(caiD_1)

PCAV:

D3880_17200

PPHN:

HU825_14485

PIZ:	LAB08_R40680

PKM:	PZ739_11735

PSHS:

PLAU:

PFOU:

PSKP:

PDEU:

PBUB:

PSML:

PSMZ:

PSWO:

PMOR:

PKH:	JLK41_05820

SDEG:

HARR:

PPHA:

HASM:

KAK:	Kalk_07795

SPL:

SHL:

COLW:

CBER:

PHA:

PTN:	PTRA_a1039(paaF)

PNG:	PNIG_a1090(paaF)

SNAN:

I6N98_06950

ZAL:	AZF00_05290

MSPN:

M8T91_14310

HJA:	BST95_08535

HALC:

AFUS:

PAQM:

MSEC:

MRZ:	KDW95_01150

EMP:	EZMO1_1290(caiD)

SDF:	ACG33_00335

SOK:	D0B54_05315

SINI:

GT972_08430

FCE:	JN531_005425

GPB:	HDN1F_27430

RIN:	ACS15_4379

REH:	H16_B0659(h16_B0659)

CNC:	CNE_2c06060(echA1)

CUH:	BJN34_30690

REU:	Reut_A1562

CTI:	RALTA_B0501

CBW:	RR42_s2331

COX:	E0W60_08240

CUK:	KB879_20740

CUPP:

CTP10_R38900

BUR:	Bcep18194_B1436

BCJ:

BCEN:

BCEO:

BCT:

BCED:

BCEP:

BPYR:

BCON:

BDF:	WI26_21295

BTEI:

BPSL:

BMEC:

BSTL:

BANN:

BARI:

BAEN:

BURK:

BURF:

BFN:

PBRY:

PPAI:

PVE:	UC34_06960

CABA:

SBC2_48860(echA8_2)

CTT:	CtCNB1_1280

CTES:

O987_07310

CRJ:	QMY55_06820

DIH:	G7047_10890

SMIO:

CATMQ487_32120

DOE:	DENOEST_1368

DENI:

B9N43_04455

AZD:	CDA09_09645

THU:	AC731_008490

THAU:

C4PIVTH_4227

THAG:

CKCBHOJB_02317(caiD)

MESS:

ABSY17_13535

AAK:	AA2016_3634

AMIS:

Amn_28120

AMIO:

N7E70_017760

GYJ:	AADW23_16465

FRB:	AB6B37_08145

NAR:

Saro_3755

NPP:	PP1Y_Mpl3023

NOV:	TQ38_027250

NOT:	C7W88_20775

NOR:	FA702_21065

NOVO:

IM701_15470 IM701_20455

SPOG:

SWI:

SPHD:

SPHM:

SPHI:

SSAN:

SPKC:

SPHA:

SLAN:

SBIN:

SPCL:

SPHB:

SPCA:

PHAO:

CNA:	AB433_04815

PHZ:	CHX26_05270

NTD:	EGO55_13735

CAEN:

K5X80_14680

HFO:	ABFZ83_09730

MTU:	Rv3550(echA20)

MTV:

RVBD_3550

MTC:

MT3654

MRA:	MRA_3589(echA20)

MTF:	TBFG_13583

MTB:	TBMG_03589

MTK:	TBSG_03616

MTZ:	TBXG_003565

MTG:	MRGA327_21925

MTI:	MRGA423_22435

MTE:	CCDC5079_3291

MTUR:

CFBS_3766(echA20)

MTL:	CCDC5180_3243

MTO:	MTCTRI2_3614(echA20)

MTD:	UDA_3550(echA20)

MTN:	ERDMAN_3895(echA20)

MTJ:	J112_19110

MTUB:

MT7199_3612

MTUE:

J114_18985

MTX:	M943_18250

MTUL:

TBHG_03490

MTUT:

HKBT1_3751(echA20)

MTUU:

HKBT2_3760(echA20)

MTQ:	HKBS1_3763(echA20)

MBO:	BQ2027_MB3580(echA20)

MBB:	BCG_3614(echA20)

MBT:	JTY_3615(echA20)

MBM:	BCGMEX_3612(echA20)

MBK:	K60_036880

MBX:

BCGT_3416

MAF:	MAF_35620(echA20)

MMIC:

RN08_3926

MCE:	MCAN_35611(echA20)

MCQ:	BN44_110042(echA)

MCV:	BN43_90048(echA)

MCX:	BN42_90045

MCZ:	BN45_100045(echA)

MORY:

MO_003707

MPA:	MAP_0516c(echA20)

MAO:

MAVI:

MAVU:

MAV:

MAVM:

MAA44156_00529(caiD_1)

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MSER:

MSA:	Mycsm_05815

MUL:	MUL_4113(echA20)

MMI:	MMAR_5039(echA20)

MMAE:

MMARE11_48490(echA20)

MLI:	MULP_05292(echA20)

MPSE:

MPSD_52380(echA20)

MSHO:

MSHO_05150(echA20)

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_11935

MYV:	G155_26220

MYE:	AB431_26450

MHAD:

B586_04550

MDX:	BTO20_31445

MSHG:

MSG_04537

MFJ:	MFLOJ_40860

MSTO:

MSTO_44830

MSIM:

MSIM_29280

MSAK:

MSAS_28940

MKU:	I2456_25585

MLW:	MJO58_24990

MXE:	MYXE_05990(echA20)

MNV:	MNVI_12340

MPAG:

C0J29_27630

MNM:	MNVM_23690

MGOR:

H0P51_25710

MCOO:

MCOO_27050

MBAI:

MB901379_04429(echA8_15)

MSEO:

MSEO_34320

MHEK:

JMUB5695_00497(echA20)

MGAU:

MGALJ_38260

MLJ:	MLAC_47570(echA20)

MBRD:

MBRA_20220(echA20)

MSHJ:

MSHI_38890(echA20)

MMAM:

K3U93_22580

MSPG:

F6B93_20370

MOT:	LTS72_28025

MPAA:

MKK62_02515

MKY:	IWGMT90018_57250

MADI:

A7U43_06850

MWU:	PT015_15455

MYW:	BVC93_09175

MYJ:	BCA37_02830

MSM:	MSMEG_6001

MSG:	MSMEI_5840(echA20)

MSB:	LJ00_29670

MSN:	LI99_29675

MSH:	LI98_29680

MVA:

Mvan_5266

MGI:

Mflv_1490

MSP:	Mspyr1_46770

MCB:	Mycch_4644

MNE:	D174_24540

MYN:	MyAD_24075

MFT:	XA26_53140

MPHL:

MPHLCCUG_00526(echA8_2)

MVQ:

MYVA_5180

MLL:	B1R94_25290

MRH:	MycrhN_2279

MTHN:

4412656_04068(caiD_11)

MHAS:

MHAS_03746(echA8_13)

MDU:	MDUV_49310

MCHT:

MCHIJ_19620

MAUU:

NCTC10437_05020(echA20)

MMAG:

MMAD_48340

MMOR:

MMOR_12120

MFX:	MFAL_32920

MAIC:

MAIC_05410

MIJ:	MINS_00360

MALV:

MALV_42510

MTY:	MTOK_22240

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_05570

MSEI:

MSEDJ_02240

MFLV:

NCTC10271_00492(echA8_2)

MCEE:

MCEL_38040

MMON:

EWR22_25340

MGO:	AFA91_10785

MHOL:

K3U96_03210

MSEN:

K3U95_25265

MPAE:

K0O64_25945

MRF:	MJO55_24005

MDF:	K0O62_25795

MCRO:

MGRO:

MAUS:

MFRE:

MBUG:

MYQ:	TUM20985_06660

MFLU:

HZU40_32885

MYH:	QU592_27215

MPAT:

MPNTM1_01951

MKR:	MKOR_35600

MPAK:

MIU77_02100

MAB:

MAB_0606c

MMV:	MYCMA_0313

MABB:

MASS_0576

MABL:

MMASJCM_0595

MCHE:

BB28_02900

MIZ:	BAB75_03650

MSTE:

MSTE_00565

MSAO:

MYCSP_02600

MSAL:

DSM43276_00524(caiD_2)

MJD:	JDM601_3704(echA20)

MTER:

4434518_03704(echA20)

MMIN:

MMIN_12280

MHIB:

MHIB_30950

MHER:

K3U94_20900

MVM:	MJO54_20800

MKK:	MU0083_003451

ASD:

AS9A_0958

NFA:	NFA_5100(echA4)

NFR:	ERS450000_03722(caiD_5)

NCY:	NOCYR_0523(echA)

NBR:	O3I_002830

NNO:	NONO_c05250

NSL:	BOX37_02290

NSR:	NS506_01290

NTP:	CRH09_03435

NOZ:	DMB37_23730

NOD:	FOH10_28540

NAH:	F5544_02765

NAD:	NCTC11293_01271(caiD_2)

NWL:	NWFMUON74_05190(paaG_3)

NIE:	KV110_03150

NHU:	H0264_03995

NYA:	LTV02_28745

NGP:	LTT66_15645

NSPU:

IFM12276_02030(paaG_2)

NYU:	D7D52_04645

NVU:	V7968_10245

RHA:	RHA1_ro04652

RER:

RER_09200

REY:

O5Y_04095

REB:	XU06_04340

RQI:	C1M55_04575

ROP:

ROP_47500

ROA:	Pd630_LPD01154

RPY:	Y013_19205

RBY:	CEJ39_05570

RAV:	AAT18_04105

RHW:	BFN03_14780

RRZ:	CS378_19740

RHOD:

AOT96_14980

RRT:	4535765_00617(echA8_3)

RCR:	NCTC10994_02104(echA8_5)

RTM:	G4H71_07210

RKO:	JWS14_25655

RGO:	KYT97_14650

ROZ:	CBI38_04825

RPSK:

RGOR:

RHOP:

RHOO:

RHOU:

RHOW:

RHOJ:

JVH1_12990(echA20)

RHOS:

RHOQ:

RHOY:

RHOH:

RHOX:

RHJS:

RSF:	OED52_02450

RHZQ:

GO592_26300

RHZG:

BO226_23620

RHBH:

A0W34_04385

RHPD:

U9J23_02885(echA20)

REQ:

REQ_07180

PDEF:

P9209_28875

PSOW:

ABI214_10050(echA20)

WHR:	OG579_09375

GBR:

Gbro_3981

GPO:	GPOL_c43030

GOR:	KTR9_3913(echA20)

GOQ:	ACH46_17555

GTA:	BCM27_20510

GOC:	CXX93_00590

GIT:	C6V83_03875

GRU:	GCWB2_20005(caiD12)

GOM:	D7316_04502(crt_18)

GAV:	C5O27_08110

GOD:	GKZ92_18930

GOS:	QAD21_19415

GOJ:	GR168_18760

GAM:	GII34_18910

GPD:	GII33_03835

GJI:	H1R19_18860

GOI:	LK459_13750

GHN:	MVF96_19445

GAMI:

IHQ52_22985

GMG:	NWF22_06425

GSI:	P5P27_01140

GOO:	HUN08_15900

GOP:	ACE11G_15665(echA20)

SPIN:

KV203_17225

TPR:

Tpau_3826

TSM:	ASU32_21805

TPUL:

TPB0596_41670(paaG_2)

TSD:	MTP03_43100(paaG_2)

DTM:	BJL86_0730

DIT:	C3V38_09375

DIZ:	CT688_03295

DPC:	A6048_03245

DLU:	A6035_03535

DKN:	NHB83_03105

DCD:	VYL96_03320

TOY:	FO059_13855

SMA:	SAVERM_6203(echA13)

SGR:

SGB:

SFI:

SANL:

SGRF:

SCYE:

SCB:	SCAB_68731(echA13)

SVL:	Strvi_4082

SRC:	M271_44255

SMAL:

SMALA_7393

SSOI:

I1A49_40730

SBH:	SBI_01731(echA3)

SVE:

SVEN_1657

SDV:	BN159_6438(echA13)

SCI:	B446_10565

SVT:	SVTN_35840

STRE:

GZL_01197

SLD:

T261_0442

SLC:	SL103_15030

STRM:

M444_10240

SPRI:

SPRI_5499

SCZ:	ABE83_27950

SCX:	AS200_32880

SRW:	TUE45_02541(caiD_1)

SCLF:

BB341_21995

SGS:	AVL59_37045

STSI:

A4E84_00885

SALW:

CP975_30885

SGM:	GCM10017557_61980(paaG)

SCAD:

DN051_28330

SPHW:

NFX46_30855

SLS:	SLINC_2343

SNR:	SNOUR_05100

SALU:

SALL:

SPLU:

SAUO:

SSIA:

SVU:	B1H20_06935

SPUN:

BFF78_01770

SGV:	B1H19_37150

SLAU:

SLA_1555

SALF:

SMD44_07228(paaF)

SALJ:

SMD11_0776(paaF)

SLX:	SLAV_27325(echA4)

STRO:

STRMOE7_04800

SFK:

KY5_7034c

SNZ:	DC008_08440

SGE:	DWG14_08121(crt_3)

SRJ:

SRO_5453

SLK:	SLUN_09825

SDX:	C4B68_30140

SGD:	ELQ87_29255

SQZ:	FQU76_06665

SCYA:

EJ357_11855

STIR:

DDW44_03305

SKA:	CP970_04890

SGZ:	C0216_23125

SVN:	CP980_24865

SHAW:

CEB94_10915

SRK:	FGW37_28070

SFIC:

EIZ62_25070

SGAL:

CP966_08905

SSPO:

DDQ41_02675

SFY:	GFH48_29890

SAQU:

EJC51_13625

SGF:	HEP81_05760

SCAV:

SRIM:

SSUB:

STSU:

SCHA:

SGX:	H4W23_38475

SCOE:

CP976_11690

SSPB:

CP982_33815

SNF:	JYK04_02667(echA8_2)

SPLA:

CP981_03335

SBRO:

GQF42_13040

STUI:

GCM10017668_16570(paaG)

SATA:

C5746_11020

SHUN:

DWB77_05716(crt_2)

SCYG:

S1361_11125(echA2)

SFEU:

IM697_11845

SDW:	K7C20_03215

SCAL:

SAUH:

SPEU:

SROI:

SXN:	IAG42_26705

SHK:	J2N69_32380

SANU:

STRY:

SGOB:

SINE:

SLF:	JEQ17_34425

SDEC:

SAOV:

SDUR:

SYAN:

SRUG:

STAA:

SNIG:

HEK616_31320(paaG_4)

SCAE:

STUB:

SSPN:

SCIR:

SXT:	KPP03845_102234(crt_1)

SLON:

LGI35_13900

STUD:

STRTU_006622

SGK:	PET44_08860

SANT:

QR300_02005

SYUN:

MOV08_04835

SJN:	RI060_31915

SCYN:

N8I84_11270

SOV:	QZH56_03640

SFIY:

F0344_28350

SKG:	KJK29_28865

SCOA:

QU709_32740

SLAI:

P8A22_33585

SROC:

RGF97_25985

SFP:	QUY26_06100

STTN:

BSL84_08700

SINN:

ABB07_34060

KBU:	Q4V64_12680

SLUO:

STPB:

SRPA:

SMIB:

SCAJ:

STRW:

STRL:

STSD:

SRPZ:

SCHE:

SCAT:

STII:

STIC:

SABD:

SPAZ:

SMOD:

SPOF:

STBR:

STAC:

STVB:

SSOC:

SSLI:

STYI:

C9F11_32950(echA3)

SCIT:

SSIR:

SEXP:

SFLU:

SSTO:

STGO:

STCM:

STID:

SCT:

SCY:	SCATT_56240

KAB:	B7C62_06820

YIA:	LO772_20220

STRH:

GXP74_18340

AGLA:

OIE69_15340

MRN:	K8F61_15965

MSUF:

KV394_02650

MWN:	QNO26_01595

ARL:	AFL94_16370

ARY:	ATC04_01495

ASUN:

KG104_09000

ARTA:

OL239_10480

GPR:	JQN66_16685

PAEY:

KUF55_17780

NCA:

Noca_2743

NDK:	I601_0610(echA8_1)

NBE:	Back2_27610

NANO:

G5V58_09890

NARO:

CFH99_13415

NPI:	G7071_15845

NPC:	KUV85_04365

NMAR:

HPC71_09630

NFC:	KG111_08430

NBI:	SHK19_12360

NOF:	MF408_21175

NOCR:

NOCW:

NOCA:

NOCL:

NOCD:

NOCQ:

PSIM:

AEB:	C6I20_03385

NGV:	CDO52_10840

TCU:

ACTW:

AMAZ:

ACIR:

AWS:	ACN3XK_01350 ACN3XK_35760 ACN3XK_36380

SPIQ:

OHA34_37855

ACTQ:

OG417_40395

SRO:

Sros_2065

NOA:	BKM31_34335

NCX:	Nocox_09775(caiD4)

NGN:	LCN96_11035

NFS:	OIE67_35995

FRI:	FraEuI1c_1264

AMD:	AMED_3377(paaG)

AMN:

RAM_17180

AMM:	AMES_3338(paaG)

AMZ:	B737_3338(paaG)

AOI:	AORI_2521(paaG)

AJA:	AJAP_26220

AMQ:	AMETH_4466(paaG)

AMYC:

CU254_23925

AMYB:

BKN51_05215

AAB:	A4R43_15950

AMYY:

YIM_33210(caiD8)

AORI:

AACD:

APRT:

AROO:

ATHM:

ARHD:

AMOG:

ACYN:

ORV05_11035 ORV05_13565

ACOR:

LCL61_01415

AMYZ:

HUW46_00307

ANW:	QP939_44020

AMYD:

ABAR:

AMYE:

AMYS:

PSDS:

KAL:

KUT:	JJ691_41360(paaG_5)

KBR:	Q4V65_07745

KPHY:

AOZ06_42545

LED:	BBK82_38835

LXR:	ACRSBM_25895

ALO:

PMAD:

SACE:

CROS:

STP:	Strop_2604

SAQ:

Sare_2803

MICB:

MicB006_5700

MCHL:

PVK74_03270

AMS:	AMIS_21700

AIH:	Aiant_18390(paaG_1)

ACTL:

L3i22_084020(paaG)

ASIC:

Q0Z83_065020

AOU:	ACTOB_004186

ACTE:

ACTI_41600(paaG_6)

DVC:	Dvina_21525

DFU:	Dfulv_25820

DROS:

DAUR:

DMAT:

DACT:

CAI:

JCY:	M6B22_17405

ABAI:

IMCC26256_111852

CWO:

Cwoe_2352

AQZ:	KSP35_09520

IAM:	HC251_18150

IMA:	PO878_16985

DHI:	LH044_15585

AHAI:

AB8619_00275

» show all

Reference

PMID:12676694

Authors

Horinouchi M, Hayashi T, Koshino H, Yamamoto T, Kudo T

Title

Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni.

Journal

Appl Environ Microbiol 69:2139-52 (2003)
DOI:10.1128/AEM.69.4.2139-2152.2003

Sequence

[ctt:CtCNB1_1280]

Reference

PMID:30194104

Authors

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

Title

Steroid Degradation in Comamonas testosteroni TA441: Identification of Metabolites and the Genes Involved in the Reactions Necessary before D-Ring Cleavage.

Journal

Appl Environ Microbiol 84 (2018)
DOI:10.1128/AEM.01324-18

Reference

PMID:28377529

Authors

Crowe AM, Casabon I, Brown KL, Liu J, Lian J, Rogalski JC, Hurst TE, Snieckus V, Foster LJ, Eltis LD.

Title

Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria.

Journal

mBio 8 (2017)
DOI:10.1128/mBio.00321-17

Sequence

[mtu:Rv3550]

LinkDB

DBGET integrated database retrieval system