KEGG   ORTHOLOGY: K28354
Entry
K28354                      KO                                     
Symbol
CYP81AN15
Name
ecgonone synthase [EC:1.14.14.194]
Pathway
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R13546  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K28354  CYP81AN15; ecgonone synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K28354  CYP81AN15; ecgonone synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.194  ecgonone synthase
     K28354  CYP81AN15; ecgonone synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP81 family
   K28354  CYP81AN15; ecgonone synthase
Genes
AG: WAA27646(CYP81AN15)
Reference
PMID:36376019
  Authors
Wang YJ, Huang JP, Tian T, Yan Y, Chen Y, Yang J, Chen J, Gu YC, Huang SX.
  Title
Discovery and Engineering of the Cocaine Biosynthetic Pathway.
  Journal
J Am Chem Soc 144:22000-22007 (2022)
DOI:10.1021/jacs.2c09091
  Sequence
[ag:WAA27646]
Reference
PMID:37068250
  Authors
Wang YJ, Tain T, Yu JY, Li J, Xu B, Chen J, D'Auria JC, Huang JP, Huang SX.
  Title
Genomic and structural basis for evolution of tropane alkaloid biosynthesis.
  Journal
Proc Natl Acad Sci U S A 120:e2302448120 (2023)
DOI:10.1073/pnas.2302448120
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