KEGG ORTHOLOGY: K28428

ORTHOLOGY: K28428

Entry

K28428                      KO

Symbol

PRR12

Name

proline-rich protein 12

Disease

H02947

Neuroocular syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K28428  PRR12; proline-rich protein 12
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Sister chromatid cohesion proteins
   Other sister chromatid cohesion factors
    K28428  PRR12; proline-rich protein 12

Genes

HSA:	57479(PRR12)

PTR:	456210(PRR12)

PPS:	100988887(PRR12)

GGO:	101149406(PRR12)

PON:	100442261(PRR12)

PPYG:

129019482(PRR12)

NLE:	100602425(PRR12)

HMH:	116478182(PRR12)

SSYN:

129459926(PRR12)

MCC:	719344(PRR12)

MCF:	102131615(PRR12)

MTHB:

126943089

MNI:	105497192(PRR12)

CSAB:

103235047(PRR12)

CATY:

105595297(PRR12)

PANU:

101012001(PRR12)

TGE:	112611906(PRR12)

MLEU:

105529021(PRR12)

RRO:	104667203(PRR12)

RBB:	108535772(PRR12)

TFN:	117091583(PRR12)

PTEH:

111519905(PRR12)

CANG:

105514863(PRR12)

CJC:	100413414(PRR12)

SBQ:	101042544(PRR12)

CIMI:

108298388(PRR12)

ANAN:

105722984(PRR12)

CSYR:

103271736(PRR12)

MMUR:

105865682(PRR12)

LCAT:

123623816(PRR12)

PCOQ:

105809402(PRR12)

OGA:	100943619(PRR12)

MMU:	233210(Prr12)

MCAL:

110298585(Prr12)

MPAH:

110316825(Prr12)

RNO:	361569(Prr12)

MCOC:

116102165(Prr12)

ANU:	117710855(Prr12)

ASYL:

127669564(Prr12)

MUN:	110546809(Prr12)

CGE:	100767720(Prr12)

MAUA:

101826410(Prr12)

PROB:

127213932(Prr12)

PLEU:

114687162(Prr12)

MORG:

121446163(Prr12)

MFOT:

126488201

AAMP:

119802475(Prr12)

NGI:	103743671(Prr12)

HGL:	101723808(Prr12)

CPOC:

100723430(Prr12)

CCAN:

109683901(Prr12)

DORD:

105994254(Prr12)

DSP:	122125859(Prr12)

DMER:

138812786(Prr12)

PLOP:

125338809(Prr12)

NCAR:

124966841

MMMA:

107151561(Prr12)

ITI:	101961003(Prr12)

OCU:

127489361

OPI:	101529239(PRR12)

TUP:	102488188(PRR12)

GVR:	103592601(PRR12)

CFA:	484377(PRR12)

CLUD:

112645141(PRR12)

VVP:	112931514(PRR12)

VLG:	121482144(PRR12)

NPO:	129500225(PRR12)

AML:	100467823(PRR12)

UMR:	103657257(PRR12)

UAH:	113243227(PRR12)

UAR:	123776248(PRR12)

ELK:

111160626

LLV:

125088770

MPUF:

101689668(PRR12)

MNP:

132005675

MLK:	131817457(PRR12)

NVS:	122911815(PRR12)

ORO:	101381105(PRR12)

EJU:	114199528(PRR12)

ZCA:	113936580(PRR12)

MLX:	117998258(PRR12)

NSU:	110572710(PRR12)

LWW:	102731296 102733038(PRR12)

FCA:	101081016(PRR12)

PYU:	121018889(PRR12)

PCOO:

112850809(PRR12)

PBG:	122493853(PRR12)

PVIV:

125152928(PRR12)

LRUF:

124510906

LGF:	123578730(PRR12)

AJU:

106983107

PTG:	102968020(PRR12)

PPAD:

109252868(PRR12)

PUC:

125915970

PLEZ:

122208098(PRR12)

HHV:	120243942(PRR12)

BTA:	529621(PRR12)

BOM:	102286601(PRR12)

BIU:	109572220(PRR12)

BBUB:

102398486(PRR12)

BBIS:

104995730(PRR12)

CHX:	102184084(PRR12)

OAS:	101112157(PRR12)

BTAX:

128063133(PRR12)

CSUM:

138096049(PRR12)

ODA:	120872126(PRR12)

CCAD:

122421008(PRR12)

MREE:

136161549(PRR12)

OVR:	110132315(PRR12)

MBEZ:

129546538(PRR12)

SSC:	100521902(PRR12)

CFR:	102517971(PRR12)

CBAI:

105062766(PRR12)

CDK:	105100237 116154946

VPC:	102527065(PRR12)

BACU:

103010234(PRR12)

BMUS:

118884991(PRR12)

LVE:	103070396(PRR12)

OOR:	101273842(PRR12)

LALB:

132510027(PRR12)

GMF:	115849069(PRR12)

DDP:	132416566(PRR12)

DLE:	111180613(PRR12)

PCAD:

102975071(PRR12)

PSIU:

116743407(PRR12)

PPHC:

136140999(PRR12)

NASI:

112415310(PRR12)

ECB:	100146713(PRR12)

EPZ:	103541760(PRR12)

EAI:	106824138(PRR12)

MYB:	102242021(PRR12)

MYD:	102771157(PRR12)

MMYO:

118655418(PRR12)

MDT:	132216176(PRR12)

MYUM:

139000086(PRR12)

PKL:	118712182(PRR12)

EFUS:

103297625(PRR12)

MNA:	107531796(PRR12)

DRO:	112310088(PRR12)

AJM:	119046001(PRR12)

PDIC:

114510863(PRR12)

PHAS:

123830256(PRR12)

MMF:	118639382(PRR12)

PPAM:

129082937(PRR12)

HAI:	109391057(PRR12)

RFQ:	117034790(PRR12)

PALE:

102882186(PRR12)

PGIG:

120615535(PRR12)

PVP:	105301790(PRR12)

RAY:	107498825(PRR12)

MJV:	108400294(PRR12)

TOD:	119249589(PRR12)

SARA:

101542357(PRR12)

SFUM:

130044206(PRR12)

SETR:

126027181(PRR12)

LAV:	100668427(PRR12)

TMU:

101349814

ETF:	101657331(PRR12)

DNM:	101425319(PRR12)

MDO:	100030306(PRR12)

GAS:

123254539

SHR:	105749970(PRR12)

AFZ:

127556540

PCW:	110219917(PRR12)

TVP:	118838689(PRR12)

PBRV:

138173339(PRR12)

MLAO:

141509865(PRR12)

OAA:	103169015(PRR12)

TACU:

119932881(PRR12)

ACYG:

136788582 136789378

TGU:	115491532(PRR12)

LSR:	110480665(PRR12)

PMOA:

120497121

OTC:

121340528

PRUF:

121351441 121356411

ATRC:

139586962(PRR12)

PHI:	102101931(PRR12)

ACOE:

138100984(PRR12)

ZLE:	135460499(PRR12)

SVG:	106864093(PRR12)

MMEA:

130587592(PRR12)

CCIC:

134057233(PRR12)

FPG:

101910742

SHAB:

115618936(PRR12)

AGEN:

126034855

HHAR:

128138501(PRR12)

NNI:

104017294

CBOY:

140644650(PRR12)

CNIC:

136001239(PRR12)

CUCA:

128849765(PRR12)

ACAR:

104531996

RTD:

128903665

LMIC:

141736810(PRR12)

AROW:

112964116(PRR12)

ASN:	102381021(PRR12)

AMJ:	106737175(PRR12)

CMY:	102938159(PRR12)

CCAY:

125628491(PRR12)

DCC:	119847215(PRR12)

CPIC:

101942956(PRR12)

CABI:

116817981(PRR12)

MRV:	120388243(PRR12)

ACS:	100567271(prr12)

ASAO:

132778111(PRR12)

PVT:	110079147(PRR12)

SUND:

121933277(PRR12)

PBI:	103060274(PRR12)

PMUR:

107282379(PRR12) 107290040

CTIG:

120313684(PRR12)

TSR:	106547863(PRR12)

PGUT:

117664469(PRR12)

PCAE:

139317396(PRR12)

APRI:

131196673(PRR12)

PTEX:

113442825(PRR12)

NSS:	113413421(PRR12)

VKO:	123030505(PRR12)

PMUA:

114581679(PRR12)

PRAF:

128400351(PRR12)

ZVI:	118094230(PRR12)

HCG:	128329377(PRR12)

GJA:	107108111(PRR12)

STOW:

125444585(PRR12)

EMC:	129338564(PRR12)

XLA:	108696728(prr12.L) 735127(prr12.S)

XTR:	100127703(prr12)

NPR:	108797514(PRR12)

RTEM:

120916500(PRR12)

ACAT:

141110679(PRR12)

BBUF:

121002513(PRR12)

BGAR:

122928595(PRR12)

DTC:	141085460(PRR12)

PWL:	138246396(PRR12)

MUO:	115466634(PRR12)

GSH:	117367536(PRR12)

DRE:	557848(prr12b) 564766(prr12a)

SRX:	107708947 107729421 107730729 107732166

SANH:

107654018 107658420 107664611 107689691

SGH:	107554076 107557376 107583015 107598586

CCAR:

109068024(prr12a) 109087768 109113716(prr12b)

CAUA:

113045694 113056390 113111983

CGIB:

127949762 127953795 127968760 128025043

PTET:

122341539(prr12b) 122355818(prr12a)

LROH:

127163521(prr12b) 127173833(prr12a)

GRF:	141297330(prr12a) 141334997(prr12b)

OMC:	131537687(prr12b) 131551455(prr12a)

PPRM:

120470449(prr12a) 120489761(prr12b)

RKG:	130080582(prr12a) 130088466(prr12b)

MAMB:

125256037(prr12a) 125277291(prr12b)

CIDE:

127508009 127523428

CERY:

137007332(prr12a) 137017599(prr12b)

MASI:

127423096 127427367 127451795

TROS:

130561053(prr12b)

TDW:	130426120(prr12b)

MANU:

129421186(prr12a) 129436049(prr12b)

PDAB:

135760146(prr12b)

IPU:	108273897(prr12a) 108274934(prr12b)

IFU:	128604308(prr12b) 128616935(prr12a)

PHYP:

113525012 113527079

SMEO:

124388680(prr12a) 124396802(prr12b)

TFD:	113648522(prr12b) 113653536(prr12a)

TVC:	132841565(prr12a) 132861026(prr12b)

CGAR:

128540950(prr12a) 128544643(prr12b)

NGRA:

132868977(prr12b) 132898034(prr12a)

TRN:	134300093(prr12b) 134321091(prr12a)

AMEX:

103033182(prr12a) 103042282(prr12b)

CMAO:

118800509(prr12b) 118809736(prr12a)

EEE:	113580281(prr12) 113590846

CHAR:

105891165(prr12a) 105898708(prr12b)

SPIL:

134070725(prr12a) 134076903(prr12b)

ASAD:

121699832(prr12a) 121705822(prr12b)

TRU:	101062379(prr12)

TFS:	130523704(prr12a)

TNG:	GSTEN00028284G001

LCO:	104924878 104935902

NCC:	104948901 104949442

TBEN:

117469365(prr12b) 117473778

CGOB:

115012063(prr12) 115024345

PGEO:

117443697 117464710(prr12a)

GACU:

117537125 117544895(prr12a)

EMAC:

134870822(prr12a) 134877496(prr12b)

ELY:	117246640(prr12a) 117269075(prr12b)

EFO:	125878798(prr12b) 125881058(prr12a)

PLEP:

121956604(prr12b) 121958415

SLUC:

116045061(prr12b) 116061475

ECRA:

117937269(prr12a) 117958222(prr12b)

ESP:	116671418 116703190(prr12)

PFLV:

114548634 114569579(prr12)

GAT:	120819796(prr12a) 120827508(prr12b)

PPUG:

119212569(prr12a) 119220149(prr12b)

AFB:	129091063 129098544(prr12b)

CLUM:

117735138(prr12b) 117748440(prr12a)

PSWI:

130188974(prr12b) 130203376(prr12a)

CANA:

137789241(prr12a) 137799073(prr12b)

CVE:	137882454(prr12b)

MSAM:

119915741 119918996(prr12b)

SCHU:

122868138(prr12a) 122869583(prr12b)

CUD:	121503980(prr12b) 121527896(prr12a)

SPUL:

138593891(prr12a) 138602496(prr12b)

LMIX:

132954670(prr12b) 132955523(prr12a)

ALAT:

119009226 119015366(prr12b)

ASTR:

137588260(prr12a)

MZE:	101465728 101474844

ONL:	100702673 100702688

OAU:	116319889(prr12a) 116333410(prr12b)

OLA:	101159141 101174673

OML:	112145940(prr12b) 112154095(prr12a)

CSAI:

133419630(prr12a) 133422774(prr12b)

XMA:	102224445(prr12) 102230057

XCO:	114147888 114151518(prr12)

XHE:	116727645(prr12) 116736236

PRET:

103468152 103481246(prr12)

PFOR:

103154717 103156830

PLAI:

106941534 106942480

PMEI:

106906107 106907694

GAF:	122821254(prr12b) 122823591(prr12a)

PPRL:

129363926 129377688

CVG:	107097214 107103919

CTUL:

119777573 119778945

GMU:	124862849 124864545 124874983

NFU:	107387992 107391811

KMR:	108237191(prr12a) 108248465(prr12b)

ALIM:

106517441 106526392(prr12) 106535387

NWH:	119423968(prr12a)

AOCE:

111579415(prr12b) 111584603(prr12a)

EJA:	138202037(prr12a) 138215504(prr12b)

BFRE:

138616967(prr12a) 138627703(prr12b)

MCEP:

124998487(prr12b) 125022297(prr12a)

CSEM:

103382031 103393519(prr12)

POV:	109646184 109646253

SSEN:

122758989(prr12a) 122785053

SSOE:

131448995(prr12a) 131475055(prr12b)

HHIP:

117753318(prr12a)

HSP:	118100399(prr12a)

PPLT:

128426596(prr12a)

SMAU:

118287968 118288687(prr12b)

LCF:	108884440 108898494(prr12b)

SDU:	111220009 111227958(prr12)

SLAL:

111655624(prr12) 111658743

XGL:	120788098(prr12b) 120794175(prr12a)

HCQ:	109523940 109524739 109524743

SSCV:

125983013(prr12b) 125990898(prr12a)

SBIA:

133495588(prr12a) 133514794(prr12b)

PEE:	133415201(prr12b) 133417731(prr12a)

PTAO:

133465980(prr12b) 133469814(prr12a)

BPEC:

110159815(prr12)

ENY:	140357824(prr12b) 140368717(prr12a)

MALB:

109963546 109964699(prr12)

BSPL:

114845282(prr12a) 114860389(prr12b)

SJO:	128378239(prr12b) 128381236(prr12a)

SSCO:

133999870(prr12b) 134003633(prr12a)

TTY:	137171491(prr12a) 137201092(prr12b)

GMH:	115530878 115558393

SASA:

106578330 106579416 106583894 106600663(prr12)

STRU:

115162640 115170761(prr12) 115191627 115200981

OTW:	112232883 112235561 112260587(prr12b) 112260614

OMY:	110491795 110498812 110521015 110538923(prr12b)

OGO:	123999755(prr12b) 124037936 124039929 124048532

ONE:	115106746 115109984(prr12) 115143939 115145251

OKI:	109865629 109881733 109893085(prr12) 109897242

OKE:	118357591 118358643 118363693 118384117(prr12b)

OMM:	135504737 135523940 135556017 135556086

OCLA:

139368294 139376463 139406874 139420905

SALP:

111971259 111976270 111977345

SNH:	120046425 120052153 120060914

SFON:

129823268(prr12b) 129854159 129855710 129860393

CCLU:

121547169 121550781 121572023 123482598(prr12b)

ELS:	105026238 105029094(prr12)

OEP:	134030821(prr12a) 134034314(prr12b)

SFM:	108925141 108941632

PKI:	111836880 111851274

AANG:

118217237(prr12b) 118220989

AROT:

135243024(prr12b) 135247998

CCOG:

133115381(prr12b) 133117583

LOC:	107075361(prr12)

PSPA:

121305887

PSEX:

120543027(prr12b)

LCM:	102350517(PRR12)

CMK:	103172339(prr12b)

RTP:

CPLA:

HOC:

LERI:

HAKA:

Reference

PMID:39742660

Authors

Nguyen AL, Smith EM, Cheeseman IM

Title

Co-essentiality analysis identifies PRR12 as a cohesin interacting protein and contributor to genomic integrity.

Journal

Dev Cell 60:1217-1233.e7 (2025)
DOI:10.1016/j.devcel.2024.12.015

Sequence

[hsa:57479]

LinkDB

DBGET integrated database retrieval system