KEGG   ORTHOLOGY: K28740
Entry
K28740                      KO                                     
Symbol
CoPKS, CrPKS
Name
6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase [EC:2.3.1.335 2.3.1.336 3.1.2.35 3.1.2.34]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.335  6-hydroxymusizin-2-carbonyl-[acyl-carrier protein] synthase
     K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
    2.3.1.336  atrochrysone-2-carbonyl-[acyl-carrier protein] synthase
     K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.34  atrochrysone-2-carbonyl-[acyl-carrier protein] thioesterase
     K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
    3.1.2.35  6-hydroxymusizin-2-carbonyl-[acyl-carrier protein] thioesterase
     K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Iterative type I PKS
   Fungal nonreducing PKS (NR-PKS)
    K28740  CoPKS, CrPKS; 6-hydroxymusizin-2-carbonyl-ACP/atrochrysone-2-carbonyl-ACP synthase/thioesterase
Other DBs
COG: COG3321 COG3319 COG0236 COG3433
Genes
AG: UMW72407(PKS1) UMW72408(PKS4) WJZ49098(PKS1) WJZ49099(PKS2) WJZ49100(PKS3)
Reference
PMID:35218274
  Authors
Lohr NA, Eisen F, Thiele W, Platz L, Motter J, Huttel W, Gressler M, Muller M, Hoffmeister D.
  Title
Unprecedented Mushroom Polyketide Synthases Produce the Universal Anthraquinone Precursor.
  Journal
Angew Chem Int Ed Engl 61:e202116142 (2022)
DOI:10.1002/anie.202116142
  Sequence
[ag:UMW72407 UMW72408]
Reference
PMID:36507600
  Authors
Lohr NA, Urban MC, Eisen F, Platz L, Huttel W, Gressler M, Muller M, Hoffmeister D.
  Title
The Ketosynthase Domain Controls Chain Length in Mushroom Oligocyclic Polyketide Synthases.
  Journal
Chembiochem 24:e202200649 (2023)
DOI:10.1002/cbic.202200649
  Sequence
[ag:UMW72407 UMW72408]
Reference
PMID:37542286
  Authors
Lohr NA, Rakhmanov M, Wurlitzer JM, Lackner G, Gressler M, Hoffmeister D.
  Title
Basidiomycete non-reducing polyketide synthases function independently of SAT domains.
  Journal
Fungal Biol Biotechnol 10:17 (2023)
DOI:10.1186/s40694-023-00164-z
  Sequence
[ag:WJZ49098 WJZ49099 WJZ49100]
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