KEGG   MODULE: M00060
Entry
M00060            Pathway   Module                                 
Name
KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type
Definition
K00677 K02535 K02536 (K03269,K09949) K00748 K00912 K02527 K02517 K02560
Diagram
M00060

Orthology
K00677  
lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] [RN:R04567]
K02535  
lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] [RN:R04587]
K02536  
lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] [RN:R04550]
K03269  
lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] [RN:R04549]
K09949  
lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] [RN:R04549]  
K00748  
lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] [RN:R04606]
K00912  
lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] [RN:R04657]
K02527  
kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13] [RN:R04658]
K02517  
lpxL, htrB; Kdo2-lipid IVA lauroyltransferase [EC:2.3.1.241] [RN:R05146]
K02560  
lpxM, msbB; lauroyl-Kdo2-lipid IVA myristoyltransferase [EC:2.3.1.243] [RN:R05075]
Class
Pathway modules; Glycan metabolism; Lipopolysaccharide metabolism
Pathway
map00540  Lipopolysaccharide biosynthesis
map01100  Metabolic pathways
Reaction
R04567  
R04587  
R04550  
R04549  
R04606  
R04657  
R04658  
R05074  
R05146  
R05075  
Compound
C00043  UDP-N-acetyl-D-glucosamine
C04738  UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
C06022  UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
C04652  UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine
C04824  2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate
C04932  2,3,2',3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate
C04919  2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
C06024  3-Deoxy-D-manno-octulosonyl-lipid IV(A)
C06025  Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
C06251  Lauroyl-KDO2-lipid IV(A)
C06026  Di[3-deoxy-D-manno-octulosonyl]-lipid A
LinkDB

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