Entry
Symbol
lpxC
Name
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:
3.5.1.108 ]
Pathway
map00540 Lipopolysaccharide biosynthesis
Module
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type
M00866 KDO2-lipid A biosynthesis, Raetz pathway, non-LpxL-LpxM type
Reaction
R04587 UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00540 Lipopolysaccharide biosynthesis
K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
09180 Brite Hierarchies
09181 Protein families: metabolism
01005 Lipopolysaccharide biosynthesis proteins
K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Enzymes [BR:ko01000 ]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.108 UDP-3-O-acyl-N-acetylglucosamine deacetylase
K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Lipopolysaccharide biosynthesis proteins [BR:ko01005 ]
Lipid A
K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
BRITE hierarchy
Other DBs
Genes
» show all
Taxonomy UniProt
Reference
Authors
Hyland SA, Eveland SS, Anderson MS
Title
Cloning, expression, and purification of UDP-3-O-acyl-GlcNAc deacetylase from Pseudomonas aeruginosa: a metalloamidase of the lipid A biosynthesis pathway.
Journal
Sequence
Reference
Authors
Hernick M, Gennadios HA, Whittington DA, Rusche KM, Christianson DW, Fierke CA
Title
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase functions through a general acid-base catalyst pair mechanism.
Journal
Sequence
Reference
Authors
Li C, Guan Z, Liu D, Raetz CR
Title
Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.
Journal
Sequence
LinkDB
All DBs