KEGG   MODULE: M00141
Entry
M00141            Pathway   Module                                 
Name
C1-unit interconversion, eukaryotes
Definition
K00600 (K00288,(K13403 K13402))
Diagram
M00141

Orthology
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1] [RN:R00945]
K00288  
methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] [RN:R01220 R01655 R00943]
K13403  
methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9] [RN:R01218 R01655]
K13402  
C1-tetrahydrofolate synthase [EC:6.3.4.3] [RN:R00943]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00670  One carbon pool by folate
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
R00945  
R01220,R01218  
R01655  
R00943  
Compound
C00101  Tetrahydrofolate
C00143  5,10-Methylenetetrahydrofolate
C00445  5,10-Methenyltetrahydrofolate
C00234  10-Formyltetrahydrofolate
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