KEGG   MODULE: M00641
Entry
M00641            Signature Module                                 
Name
Multidrug resistance, efflux pump MexEF-OprN
Definition
K18297 K18298+K18299-K18300
Diagram
M00641

Orthology
K18297  
mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
K18298  
mexE; membrane fusion protein
K18299  
mexF; multidrug efflux pump
K18300  
oprN; outer membrane protein
Class
Signature modules; Gene set; Drug resistance
Reference
  Authors
Tian ZX, Mac Aogain M, O'Connor HF, Fargier E, Mooij MJ, Adams C, Wang YP, O'Gara F
  Title
MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump.
  Journal
Microb Pathog 47:237-41 (2009)
DOI:10.1016/j.micpath.2009.08.003
Reference
  Authors
Depardieu F, Podglajen I, Leclercq R, Collatz E, Courvalin P
  Title
Modes and modulations of antibiotic resistance gene expression.
  Journal
Clin Microbiol Rev 20:79-114 (2007)
DOI:10.1128/CMR.00015-06
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