KEGG   MODULE: M00763
Entry
M00763            Pathway   Module                                 
Name
Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Definition
K05826
K19412 K05828 K05829 K05830 K05831
Diagram
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00763

Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
map00220  Arginine biosynthesis
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Orthology
K05826  
glutamate carrier protein LysW
K19412  
glutamate--LysW ligase ArgX [EC:6.3.2.-] [RN:R10929]
K05828  
LysW-L-glutamate kinase [EC:2.7.2.19] [RN:R10930]
K05829  
LysW-L-glutamyl-5-phosphate reductase [EC:1.2.1.-] [RN:R10931]
K05830  
LysW-L-ornithine aminotransferase [EC:2.6.1.124] [RN:R10932]
K05831  
LysW-L-ornithine hydrolase [EC:3.5.1.132] [RN:R10933]
Complete
hdl  Halobacterium sp. DL1
hhb  Halobacterium hubeiense
hno  Halobacterium noricense
hlu  Halobacterium litoreum
hanx  Halobacterium sp. NMX12-1
halh  Halodesulfurarchaeum formicicum HTSR1
hhsr  Halodesulfurarchaeum formicicum HSR6
hsu  Halanaeroarchaeum sulfurireducens HSR2
hsf  Halanaeroarchaeum sulfurireducens M27-SA2
hahs  Halanaeroarchaeum sp. HSR-CO
salr  Salarchaeum sp. JOR-1
halr  Halarchaeum sp. CBA1220
hje  Halalkalicoccus jeotgali
hdo  Halococcus dombrowskii
halx  Halorussus limi
haxz  Halorussus gelatinilyticus
hayc  Halorussus salilacus
haxy  Halorussus vallis
sali  Salinarchaeum sp. Harcht-Bsk1
saim  Salinarchaeum sp. IM2453
hara  Natranaeroarchaeum sulfidigenes
hma  Haloarcula marismortui ATCC 43049
hsin  Haloarcula marismortui ATCC 33800
hhi  Haloarcula hispanica ATCC 33960
hhn  Haloarcula hispanica N601
hab  Haloarcula sp. CBA1115
hta  Haloarcula taiwanensis
halj  Haloarcula sp. JP-L23
hut  Halorhabdus utahensis
hti  Halorhabdus tiamatea
hala  Halorhabdus sp. CBA1104
hasv  Halorhabdus sp. SVX81
habn  Halorhabdus sp. BNX81
hmu  Halomicrobium mukohataei
halz  Halomicrobium mukohataei JP60
hall  Halomicrobium sp. LC1Hm
hazp  Halomicrobium sp. ZPS1
hali  Halorientalis sp. IM1011
hsn  Halapricum salinum
hds  Halapricum desulfuricans
hrr  Halosimplex rubrum
hpel  Halosimplex pelagicum
hlt  Halosimplex litoreum
harc  Halococcoides cellulosivorans
ssai  Salinirubellus salinus
haad  Halocatena salina
nph  Natronomonas pharaonis
nmo  Natronomonas moolapensis
nho  Natronomonas halophila
nsal  Natronomonas salina
hwa  Haloquadratum walsbyi DSM 16790
hwc  Haloquadratum walsbyi C23
hvo  Haloferax volcanii DS2
hale  Haloferax volcanii wsp1
hln  Haloferax volcanii SVX82
hme  Haloferax mediterranei
hgi  Haloferax gibbonsii
hls  Haloferax larsenii
hbo  Halogeometricum borinquense
haq  Haloplanus rubicundus CBA1112
haj  Haloplanus rubicundus CBA1113
haer  Haloplanus aerogenes
hra  Haloplanus rallus
hlm  Halobellus limi
halm  Haloprofundus sp. MHR1
hla  Halorubrum lacusprofundi
halp  Halorubrum sp. PV6
halb  Halorubrum sp. BOL3-1
hezz  Halorubrum ezzemoulense
halq  Halorubrum sp. CBA1229
hss  Halorubrum ruber
hsai  Halorubrum salinarum
hazz  Halorubrum sp. 2020YC2
hae  Halohasta litchfieldiae
haln  Halolamina sp. CBA1230
halg  Halorarum halophilum
halu  Halorarum salinum
hmp  Halobaculum magnesiiphilum
hre  Halobaculum roseum
hrm  Halobaculum rubrum
hacb  Halobaculum sp. CBA1158
hdf  Halalkaliarchaeum desulfuricum
haaa  Halalkaliarchaeum sp. AArc-CO
hah  Halophilic archaeon
htu  Haloterrigena turkmenica
hsal  Haloterrigena salifodinae
hakz  Haloterrigena alkaliphila
nmg  Natrialba magadii
hxa  Halopiger xanaduensis
nat  Natrinema sp. J7-2
npe  Natrinema pellirubrum
nvr  Natrinema versiforme
npl  Natrinema pallidum
nay  Natrinema zhouii
haly  Natrinema halophilum
hjt  Natrinema thermotolerans
hlo  Natrinema longum
nge  Natronobacterium gregoryi
hlc  Natronobacterium lacisalsi
hru  Halovivax ruber
sawl  Natronosalvus rutilus
halv  Natronosalvus halobius
nou  Natronococcus occultus
hlr  Halostagnicola larsenii
naj  Natrarchaeobaculum aegyptiacum
nag  Natrarchaeobaculum sulfurireducens AArc-Mg
nara  Natrialbaceae archaeon AArc-T1-2
nbg  Natronorubrum bangense
nas  Natronorubrum aibiense
hda  Natronorubrum daqingense
fai  Ferroplasma acidiphilum
iho  Ignicoccus hospitalis
iis  Ignicoccus islandicus
pfm  Pyrolobus fumarii
pdl  Pyrodictium delaneyi
pabi  Pyrodictium abyssi
pare  Pyrofollis japonicus
sto  Sulfurisphaera tokodaii
soh  Sulfurisphaera ohwakuensis
sjv  Sulfurisphaera javensis
sso  Saccharolobus solfataricus P2
sol  Saccharolobus solfataricus 98/2
ssoa  Saccharolobus solfataricus SULA
ssol  Saccharolobus solfataricus SARC-B
ssof  Saccharolobus solfataricus SARC-C
sshi  Saccharolobus shibatae
scas  Saccharolobus caldissimus
sis  Saccharolobus islandicus L.S.2.15
sia  Saccharolobus islandicus M.14.25
sim  Saccharolobus islandicus M.16.27
sid  Saccharolobus islandicus M.16.4
siy  Saccharolobus islandicus Y.G.57.14
sin  Saccharolobus islandicus Y.N.15.51
sii  Saccharolobus islandicus L.D.8.5
sih  Saccharolobus islandicus HVE10/4
sir  Saccharolobus islandicus REY15A
sic  Saccharolobus islandicus LAL14/1
sula  Saccharolobus sp. A20
sule  Saccharolobus sp. E5-1-F
sai  Sulfolobus acidocaldarius DSM 639
sacn  Sulfolobus acidocaldarius N8
sacr  Sulfolobus acidocaldarius Ron12/I
sacs  Sulfolobus acidocaldarius SUSAZ
sull  Sulfolobus sp. S-194
mse  Metallosphaera sedula DSM 5348
memj  Metallosphaera sedula MJ1HA
mpru  Metallosphaera sedula Ron 12/II
mcn  Metallosphaera cuprina
mhk  Metallosphaera hakonensis JCM 8857 = DSM 7519
mten  Metallosphaera tengchongensis
mjn  Metallosphaera javensis
aho  Acidianus hospitalis
aman  Acidianus manzaensis
abri  Acidianus brierleyi
asul  Acidianus sulfidivorans
aamb  Acidianus ambivalens
acih  Acidianus sp. HS-5
sacd  Sulfodiicoccus acidiphilus
sazo  Stygiolobus azoricus
csty  Stygiolobus caldivivus
step  Sulfuracidifex tepidarius
pyr  Pyrobaculum ferrireducens
tne  Pyrobaculum neutrophilum
pyw  Pyrobaculum sp. WP30
tuz  Thermoproteus uzoniensis
vdi  Vulcanisaeta distributa
csu  Caldarchaeum subterraneum
 » show all
Reaction
R10929  
R10930  
R10931  
R10932  
R10933  
Compound
C00025  L-Glutamate
C20948  LysW-L-glutamate
C20949  LysW-L-glutamyl 5-phosphate
C20950  LysW-L-glutamate 5-semialdehyde
C20951  LysW-L-ornithine
C00077  L-Ornithine
RModule
RM002  Carboxyl to amino conversion using protective N-acetyl group (basic amino acid synthesis)
Reference
PMID:23434852
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
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