KEGG   MODULE: M00803
Entry
M00803            Pathway   Module                                 
Name
dTDP-D-angolosamine biosynthesis
Definition
K16435 K19859 K16436 K13332
Diagram
M00803

Orthology
K16435  
ang4; dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159] [RN:R05518]
K19859  
ang14; dTDP-4-keto-6-deoxyhexose reductase [RN:R08927]
K16436  
angB; dTDP-2,6-dideoxy-D-kanosamine transaminase [RN:R08928]
K13332  
angMI; N,N-dimethyltransferase [RN:R08929]
Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Polyketide sugar unit biosynthesis
Pathway
map00523  Polyketide sugar unit biosynthesis
map01250  Biosynthesis of nucleotide sugars
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R05518  
R08927  
R08928  
R08929  
Compound
C11907  dTDP-4-oxo-6-deoxy-D-glucose
C06620  dTDP-3,4-dioxo-2,6-dideoxy-D-glucose
C18029  dTDP-3-oxo-2,6-dideoxy-D-glucose
C18030  dTDP-2,6-dideoxy-D-kanosamine
C18031  dTDP-D-angolosamine
RModule
RM035  Transamination and N,N-dimethylation in polyketide biosynthesis
Reference
PMID:18802638
  Authors
Schell U, Haydock SF, Kaja AL, Carletti I, Lill RE, Read E, Sheehan LS, Low L, Fernandez MJ, Grolle F, McArthur HA, Sheridan RM, Leadlay PF, Wilkinson B, Gaisser S
  Title
Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
  Journal
Org Biomol Chem 6:3315-27 (2008)
DOI:10.1039/b807914e
LinkDB

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