KEGG   MODULE: M00916
Entry
M00916            Pathway   Module                                 
Name
Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
Definition
K06215+K08681
Diagram
M00916

Orthology
K06215  
pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] [RN:R10089]
K08681  
pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] [RN:R10089]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00750  Vitamin B6 metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
Compound
C00117  D-Ribose 5-phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00064  L-Glutamine
C00018  Pyridoxal phosphate
Reference
  Authors
Fitzpatrick TB, Amrhein N, Kappes B, Macheroux P, Tews I, Raschle T
  Title
Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.
  Journal
Biochem J 407:1-13 (2007)
DOI:10.1042/BJ20070765
Reference
  Authors
Raschle T, Amrhein N, Fitzpatrick TB
  Title
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.
  Journal
J Biol Chem 280:32291-300 (2005)
DOI:10.1074/jbc.M501356200
Reference
  Authors
Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB.
  Title
Vitamin B6 biosynthesis in higher plants.
  Journal
Proc Natl Acad Sci U S A 102:13687-92 (2005)
DOI:10.1073/pnas.0506228102
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