KEGG   MODULE: M00963
Entry
M00963            Pathway   Module                                 
Name
Chanoclavine aldehyde biosynthesis, tryptophan => chanoclavine-I aldehyde
Definition
K14130 K18884 K17746
Diagram
M00963  Chanoclavine aldehyde biosynthesis, tryptophan => chanoclavine-I aldehyde
M00963

Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of phytochemical compounds
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K14130  
tryptophan 4-dimethylallyltransferase [EC:2.5.1.34] [RN:R01657]
K18884  
4-dimethylallyltryptophan N-methyltransferase [EC:2.1.1.261] [RN:R10166]
K17746  
chanoclavine-I dehydrogenase [EC:1.1.1.332] [RN:R10128]
Complete
maw  Metarhizium acridum
maj  Metarhizium robertsii
mbrn  Metarhizium brunneum
glz  Glarea lozoyensis
afm  Aspergillus fumigatus
abe  Trichophyton benhamiae
tve  Trichophyton verrucosum
Reaction
R01657  
R10166  
R12104  
R10128  
Compound
C00078  L-Tryptophan
C04290  4-(3-Methylbut-2-enyl)-L-tryptophan
C20410  4-Dimethylallyl-L-abrine
C09131  Chanoclavine-I
C20379  Chanoclavine-I aldehyde
Reference
PMID:22403186
  Authors
Wallwey C, Heddergott C, Xie X, Brakhage AA, Li SM
  Title
Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae.
  Journal
Microbiology 158:1634-44 (2012)
DOI:10.1099/mic.0.056796-0
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