KEGG   MODULE: M01060
Entry
M01060            Pathway   Module                                 
Name
Petrobactin biosynthesis, spermidine => petrobactin
Definition
K15652 K24110 K24111
K24108 K24109 K24112
Diagram
M01060  Petrobactin biosynthesis, spermidine => petrobactin
M01060

Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other bacterial compounds
Pathway
map00975  Biosynthesis of various siderophores
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K15652  
asbF; 3-dehydroshikimate dehydratase [EC:4.2.1.118] [RN:R01627]
K24110  
asbC; 3,4-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.2.1.62] [RN:R12576 R12577]
K24111  
asbD; aryl carrier protein AsbD
K24108  
asbA; spermidine-citrate ligase [EC:6.3.2.-] [RN:R12596]
K24109  
asbB; 3,4-dihydroxybenzoyl-citryl-spermidine/N-citryl-spermidine--spermidine ligase [EC:6.3.2.-] [RN:R12598 R12599]
K24112  
asbE; petrobactin synthase [EC:2.-.-.-] [RN:R12600 R12597 R12601]
Complete
maq  Marinobacter nauticus VT8
mhc  Marinobacter nauticus ATCC 49840
marj  Marinobacter sp. JH2
mshe  Marinobacter shengliensis
mrx  Marinobacter sp. RI1
ban  Bacillus anthracis Ames
bar  Bacillus anthracis Ames Ancestor
bat  Bacillus anthracis Sterne
bah  Bacillus anthracis CDC 684
bax  Bacillus anthracis H9401
bant  Bacillus anthracis A16
banr  Bacillus anthracis A16R
bans  Bacillus anthracis SVA11
banh  Bacillus anthracis HYU01
banv  Bacillus anthracis Vollum
bal  Bacillus cereus biovar anthracis CI
bce  Bacillus cereus ATCC 14579
bcz  Bacillus cereus E33L
bcb  Bacillus cereus B4264
bcu  Bacillus cereus AH820
bcg  Bacillus cereus G9842
bcx  Bacillus cereus 03BB102
bcf  Bacillus cereus F837/76
btk  Bacillus thuringiensis serovar konkukian 97-27
btl  Bacillus thuringiensis Al Hakam
btb  Bacillus thuringiensis BMB171
btt  Bacillus thuringiensis serovar kurstaki HD73
bthr  Bacillus thuringiensis serovar kurstaki YBT-1520
bthi  Bacillus thuringiensis serovar kurstaki HD-1
btc  Bacillus thuringiensis serovar chinensis CT-43
btg  Bacillus thuringiensis Bt407
bti  Bacillus thuringiensis HD-771
btn  Bacillus thuringiensis HD-789
btht  Bacillus thuringiensis serovar thuringiensis IS5056
bthu  Bacillus thuringiensis YBT-1518
btw  Bacillus thuringiensis HD1011
bthy  Bacillus thuringiensis YWC2-8
bwe  Bacillus mycoides KBAB4
bww  Bacillus mycoides WSBC 10204
bmyo  Bacillus mycoides ATCC 6462
btm  Bacillus toyonensis biovar Thuringiensis
bty  Bacillus toyonensis BCT-7112
bby  Bacillus bombysepticus
bwd  Bacillus wiedmannii
btro  Bacillus tropicus
bmob  Bacillus mobilis
bnt  Bacillus nitratireducens
balu  Bacillus albus
bpam  Bacillus paramobilis
bard  Bacillus arachidis
basd  Bacillus sp. SD-4
bham  Bacillus haimaensis
baez  Bacillus sp. E25
baaz  Bacillus sp. A260
bhk  Sutcliffiella horikoshii
bcl  Shouchella clausii
ble  Shouchella lehensis
shua  Shouchella hunanensis
bpf  Alkalihalophilus pseudofirmus
bon  Cytobacillus oceanisediminis
cfir  Cytobacillus firmus
cpss  Cytobacillus pseudoceanisediminis
lsp  Lysinibacillus sphaericus
lfu  Lysinibacillus fusiformis
llb  Lysinibacillus louembei
lyq  Lysinibacillus sp. Ag94
lyo  Lysinibacillus sp. OF-1
lyr  Lysinibacillus sp. RS11
mlit  Metabacillus litoralis
mebz  Metabacillus sp. B2-18
bwh  Metabacillus harenarius
ecto  Ectobacillus sp. JY-23
alkl  Alkalihalobacillus sp. LMS39
exm  Exiguobacterium sp. MH3
exu  Exiguobacterium sp. U13-1
bbe  Brevibacillus brevis
blr  Brevibacillus laterosporus
bfm  Brevibacillus formosus
brw  Brevibacillus sp. 7WMA2
pms  Paenibacillus mucilaginosus KNP414
pmq  Paenibacillus mucilaginosus 3016
pmw  Paenibacillus mucilaginosus K02
palr  Paenibacillus albicereus
sob  Solibacillus sp. R5-41
 » show all
Reaction
R01627  
R12576  
R12577  
R12596  
R12598  
R12600  
R12597  
R12599  
R12601  
Compound
C02637  3-Dehydroshikimate
C00230  3,4-Dihydroxybenzoate
C20884  (3,4-Dihydroxybenzoyl)adenylate
C20883  3,4-Dihydroxybenzoyl-[aryl-carrier protein]
C00315  Spermidine
C00158  Citrate
C20885  N-Citryl-spermidine
C22004  N8,N'8-Citryl-bis(spermidine)
C22069  N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine)
C20952  N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine
C22273  Petrobactin
Reference
PMID:18758617
  Authors
Oves-Costales D, Kadi N, Fogg MJ, Song L, Wilson KS, Challis GL
  Title
Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative.
  Journal
Chem Commun (Camb) 4034-6 (2008)
DOI:10.1039/b809353a
Reference
PMID:18955706
  Authors
Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH
  Title
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
  Journal
Proc Natl Acad Sci U S A 105:17133-8 (2008)
DOI:10.1073/pnas.0808118105
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