| Entry |
|
| Name |
HCV NS5A to PI3K signaling pathway
|
| Definition |
NS5A -> PI3K |
| Expanded |
K22275 -> (5290,5291,5293) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
| H00048 | Hepatocellular carcinoma |
|
| Gene |
| 5290 | PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| 5291 | PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| 5293 | PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
|
| Perturbant |
| K22275 (NS5A) | NS5A; HCV non-structural protein 5A |
|
| Reference |
|
| Authors |
Macdonald A, Harris M |
| Title |
Hepatitis C virus NS5A: tales of a promiscuous protein. |
| Journal |
|
| Reference |
|
| Authors |
Panteva M, Korkaya H, Jameel S |
| Title |
Hepatitis viruses and the MAPK pathway: is this a survival strategy? |
| Journal |
|
| Reference |
|
| Authors |
He Y, Nakao H, Tan SL, Polyak SJ, Neddermann P, Vijaysri S, Jacobs BL, Katze MG |
| Title |
Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. |
| Journal |
|
| LinkDB |
|