| Entry |
|
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| Name |
|
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| Definition |
(ATM,ATR) -> TADA3 -> EP300 -> TP53 => CDKN1A -| (CCND+CDK4/6) -> RB1 // E2F |
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| Expanded |
(472,545) -> 10474 -> 2033 -> 7157 => 1026 -| ((595,894,896)+(1019,1021)) -> 5925 // (1869,1870,1871) |
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| Class |
|
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| Type |
Reference
|
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| Pathway |
|
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| Gene |
| 472 | ATM; ATM serine/threonine kinase |
| 545 | ATR; ATR serine/threonine kinase |
| 10474 | TADA3; transcriptional adaptor 3 |
| 2033 | EP300; E1A binding protein p300 |
| 7157 | TP53; tumor protein p53 |
| 1026 | CDKN1A; cyclin dependent kinase inhibitor 1A |
| 1019 | CDK4; cyclin dependent kinase 4 |
| 1021 | CDK6; cyclin dependent kinase 6 |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
| 1870 | E2F2; E2F transcription factor 2 |
| 1871 | E2F3; E2F transcription factor 3 |
|
|---|
| Reference |
|
|---|
| Authors |
Vuong L, Conley SM, Al-Ubaidi MR |
|---|
| Title |
Expression and role of p53 in the retina. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Chand V, Nandi D, Mangla AG, Sharma P, Nag A |
|---|
| Title |
Tale of a multifaceted co-activator, hADA3: from embryogenesis to cancer and beyond. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Nag A, Germaniuk-Kurowska A, Dimri M, Sassack MA, Gurumurthy CB, Gao Q, Dimri G, Band H, Band V |
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| Title |
An essential role of human Ada3 in p53 acetylation. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Wong PP, Pickard A, McCance DJ |
|---|
| Title |
p300 alters keratinocyte cell growth and differentiation through regulation of p21(Waf1/CIP1). |
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| Journal |
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| LinkDB |
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