KEGG   NETWORK: N00358
Entry
N00358                      Network                                
Name
HPV E6 to p21-cell cycle G1/S
Definition
(E6+UBE3A) -| TP53
  Expanded
(K21807+7337) -| 7157
Class
nt06130 Cell cycle (viruses)
nt06166 Human papillomavirus (HPV)
Type
Pathogen
Pathway
hsa05165  Human papillomavirus infection
Disease
H00030  Cervical cancer
Gene
7337  UBE3A; ubiquitin protein ligase E3A
7157  TP53; tumor protein p53
Perturbant
K21807 (E6)  E6; HPV protein E6
Reference
  Authors
Munger K
  Title
The role of human papillomaviruses in human cancers.
  Journal
Front Biosci 7:d641-9 (2002)
DOI:10.2741/a800
Reference
  Authors
Chocolatewala NM, Chaturvedi P
  Title
Role of human papilloma virus in the oral carcinogenesis: an Indian perspective.
  Journal
J Cancer Res Ther 5:71-7 (2009)
DOI:10.4103/0973-1482.52788
Reference
  Authors
Moody CA, Laimins LA
  Title
Human papillomavirus oncoproteins: pathways to transformation.
  Journal
Nat Rev Cancer 10:550-60 (2010)
DOI:10.1038/nrc2886
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