| Entry |
|
| Name |
EBV EBNA3C to cell cycle G1/S
|
| Definition |
EBNA3C -> (CCND+CDK4/6) -> RB1 // E2F |
| Expanded |
K19458 -> ((595,894,896)+(1019,1021)) -> 5925 // (1869,1870,1871) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
|
| Gene |
| 1019 | CDK4; cyclin dependent kinase 4 |
| 1021 | CDK6; cyclin dependent kinase 6 |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
| 1870 | E2F2; E2F transcription factor 2 |
| 1871 | E2F3; E2F transcription factor 3 |
|
| Perturbant |
| K19458 (EBNA3C) | EBNA6; EBV nuclear antigen 6 |
|
| Reference |
|
| Authors |
Saha A, Robertson ES |
| Title |
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes. |
| Journal |
|
| Reference |
|
| Authors |
Saha A, Halder S, Upadhyay SK, Lu J, Kumar P, Murakami M, Cai Q, Robertson ES |
| Title |
Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1. |
| Journal |
|
| LinkDB |
|