NETWORK: N00512
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Entry
N00512 Network
Name
HTLV-1 Tax to c-myc-mediated transcription
Definition
TAX -| MYC => TERT
Expanded
K21857 -| 4609 => 7015
Type
Pathogen
Pathway
hsa05166
Human T-cell leukemia virus 1 infection
Disease
H00009
Adult T-cell leukemia
Gene
4609
MYC; MYC proto-oncogene, bHLH transcription factor
7015
TERT; telomerase reverse transcriptase
Perturbant
K21857
(TAX)
tax; HTLV protein Tax-1
Reference
PMID:
12802280
Authors
Gabet AS, Mortreux F, Charneau P, Riou P, Duc-Dodon M, Wu Y, Jeang KT, Wattel E
Title
Inactivation of hTERT transcription by Tax.
Journal
Oncogene 22:3734-41 (2003)
DOI:
10.1038/sj.onc.1206468
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