KEGG   ORTHOLOGY: K21857
Entry
K21857                      KO                                     
Symbol
tax
Name
Deltaretrovirus protein Tax-1
Pathway
map03230  Viral genome structure
map05166  Human T-cell leukemia virus 1 infection
map05203  Viral carcinogenesis
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06214  PI3K signaling (cancer)
nt06218  TGFB signaling (cancer)
nt06223  TNF signaling (cancer)
nt06230  Cell cycle (cancer)
nt06507  TGFB signaling
nt06516  TNF signaling
  Element
N00221  HTLV-1 Tax to spindle assembly checkpoint signaling
N00222  HTLV-1 Tax to spindle assembly checkpoint signaling
N00494  HTLV-1 Tax to p16-cell cycle G1/S
N00495  HTLV-1 Tax to p15-cell cycle G1/S
N00497  HTLV-1 Tax to p21-cell cycle G1/S
N00498  HTLV-1 Tax to p21-cell cycle G1/S
N00500  HTLV-1 Tax to p21-cell cycle G2/M
N00501  HTLV-1 Tax to EGFR-PI3K-NFKB signaling pathway
N00502  HTLV-1 Tax to PTEN-PIP3-AKT signaling pathway
N00503  HTLV-1 Tax to TNF-JNK signaling pathway
N00504  HTLV-1 Tax to NFKB signaling pathway
N00506  HTLV-1 Tax to CD40-NFKB signaling pathway
N00507  HTLV-1 Tax to TGF-beta signaling pathway
N00508  HTLV-1 Tax to NFY-mediated transcription
N00509  HTLV-1 Tax to SRF-mediated transcription
N00510  HTLV-1 Tax to CREB-mediated transcription
N00511  HTLV-1 Tax to E47-mediated transcription
N00512  HTLV-1 Tax to c-myc-mediated transcription
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K21857  tax; Deltaretrovirus protein Tax-1
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K21857  tax; Deltaretrovirus protein Tax-1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K21857  tax; Deltaretrovirus protein Tax-1
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21857  tax; Deltaretrovirus protein Tax-1
Viral proteins [BR:ko03200]
 ssRNA-RT viruses
  Human T-cell leukemia virus
   K21857  tax; Deltaretrovirus protein Tax-1
Genes
VG: 13230767(STLV-6_gp4) 1491938(tax) 1491946(HTLV2gp5) 1497204(STLV1gp4) 1724972(STLV2gp07) 7205460(tax) 929294(tax)
Reference
  Authors
Geddes VE, Jose DP, Leal FE, Nixon DF, Tanuri A, Aguiar RS
  Title
HTLV-1 Tax activates HIV-1 transcription in latency models.
  Journal
Virology 504:45-51 (2017)
DOI:10.1016/j.virol.2017.01.014
  Sequence
[vg:1491938]
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