KEGG   NETWORK: N00522
Entry
N00522                      Network                                
Name
HCV NS3 to p21-cell cycle G1/S
Definition
NS3 -| TP53
  Expanded
K22273 -| 7157
Class
nt06263 Hepatocellular carcinoma
nt06130 Cell cycle (viruses)
nt06163 Hepatitis C virus (HCV)
Type
Pathogen
Pathway
hsa05160  Hepatitis C
Disease
H00048  Hepatocellular carcinoma
Gene
7157  TP53; tumor protein p53
Perturbant
K22273 (NS3)  NS3; HCV serine protease NS3
Reference
  Authors
Kwun HJ, Jung EY, Ahn JY, Lee MN, Jang KL
  Title
p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3.
  Journal
J Gen Virol 82:2235-41 (2001)
DOI:10.1099/0022-1317-82-9-2235
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