| Entry |
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| Name |
HCV core to RXRA/LXRA-mediated transcription
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| Definition |
(Core+PSME3) -> (RXRA+NR1H3) => (CCND1,CDK4,MYC) |
|---|
| Expanded |
(K22271+10197) -> (6256+10062) => (595,1019,4609) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
| H00048 | Hepatocellular carcinoma |
|
|---|
| Gene |
| 10197 | PSME3; proteasome activator subunit 3 |
| 6256 | RXRA; retinoid X receptor alpha |
| 10062 | NR1H3; nuclear receptor subfamily 1 group H member 3 |
| 1019 | CDK4; cyclin dependent kinase 4 |
| 4609 | MYC; MYC proto-oncogene, bHLH transcription factor |
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| Perturbant |
| K22271 (Core) | Core; HCV core protein |
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| Reference |
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| Authors |
Tan A, Yeh SH, Liu CJ, Cheung C, Chen PJ |
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| Title |
Viral hepatocarcinogenesis: from infection to cancer. |
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| Journal |
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| Reference |
|
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| Authors |
Hassan M, Selimovic D, El-Khattouti A, Ghozlan H, Haikel Y, Abdelkader O |
|---|
| Title |
Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies. |
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| Journal |
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| LinkDB |
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