KEGG   NETWORK: N00565
Entry
N00565                      Network                                
Name
HSV US11 to RIG-I-like receptor signaling pathway
Definition
US11 -| (DDX58,IFIH1)
  Expanded
K19438 -| (23586,64135)
Class
nt06133 RLR signaling (viruses)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
23586  DDX58; DExD/H-box helicase 58
64135  IFIH1; interferon induced with helicase C domain 1
Perturbant
K19438 (US11)  US11; HSV1 RNA-binding protein
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Xing J, Wang S, Lin R, Mossman KL, Zheng C
  Title
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5.
  Journal
J Virol 86:3528-40 (2012)
DOI:10.1128/JVI.06713-11
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