| Entry |
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| Name |
HSV US11 to PKR-eIF2alpha signaling pathway
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| Definition |
US11 -| EIF2AK2 |
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| Expanded |
K19438 -| 5610 |
|---|
| Class |
nt06168 Herpes simplex virus 1 (HSV-1)
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| Type |
Pathogen
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| Pathway |
| hsa05168 | Herpes simplex virus 1 infection |
|
|---|
| Disease |
| H00365 | Herpes simplex virus infection |
|
|---|
| Gene |
| 5610 | EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2 |
|
|---|
| Perturbant |
| K19438 (US11) | US11; HSV1 RNA-binding protein |
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|---|
| Reference |
|
|---|
| Authors |
Poppers J, Mulvey M, Khoo D, Mohr I |
|---|
| Title |
Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein. |
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| Journal |
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|---|
| Reference |
|
|---|
| Authors |
Leib DA |
|---|
| Title |
Counteraction of interferon-induced antiviral responses by herpes simplex viruses. |
|---|
| Journal |
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| Reference |
|
|---|
| Authors |
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A |
|---|
| Title |
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR. |
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| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Walsh D, Mohr I |
|---|
| Title |
Viral subversion of the host protein synthesis machinery. |
|---|
| Journal |
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| LinkDB |
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