KEGG   NETWORK: N00748
Entry
N00748                      Network                                
Name
GPI-anchor biosynthesis
Definition
PI+UDP-GlcNAc -- (PIGA+PIGC+PIGH+PIGP+PIGQ+PIGY+DPM2) >> PIGL >> PIGW >> (PIGM+PIGX) >> PIGV >> PIGN >> PIGB >> (PIGO+PIGF) >> (PIGG+PIGF) >> (GPAA1+PIGK+PIGS+PIGT+PIGU) -> G13150
  Expanded
(C01194+G10610) -- (5277+5279+5283+51227+9091+84992+8818) >> 9487 >> 284098 >> (93183+54965) >> 55650 >> 23556 >> 9488 >> (84720+5281) >> (54872+5281) >> (8733+10026+94005+51604+128869) -> G13150
Class
nt06018 GPI-anchor biosynthesis
Type
Reference
Pathway
hsa00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Gene
5277  PIGA; phosphatidylinositol glycan anchor biosynthesis class A
5279  PIGC; phosphatidylinositol glycan anchor biosynthesis class C
5283  PIGH; phosphatidylinositol glycan anchor biosynthesis class H
51227  PIGP; phosphatidylinositol glycan anchor biosynthesis class P
9091  PIGQ; phosphatidylinositol glycan anchor biosynthesis class Q
84992  PIGY; phosphatidylinositol glycan anchor biosynthesis class Y
8818  DPM2; dolichyl-phosphate mannosyltransferase subunit 2, regulatory
9487  PIGL; phosphatidylinositol glycan anchor biosynthesis class L
284098  PIGW; phosphatidylinositol glycan anchor biosynthesis class W
93183  PIGM; phosphatidylinositol glycan anchor biosynthesis class M
54965  PIGX; phosphatidylinositol glycan anchor biosynthesis class X
55650  PIGV; phosphatidylinositol glycan anchor biosynthesis class V
23556  PIGN; phosphatidylinositol glycan anchor biosynthesis class N
9488  PIGB; phosphatidylinositol glycan anchor biosynthesis class B
84720  PIGO; phosphatidylinositol glycan anchor biosynthesis class O
5281  PIGF; phosphatidylinositol glycan anchor biosynthesis class F
54872  PIGG; phosphatidylinositol glycan anchor biosynthesis class G
8733  GPAA1; glycosylphosphatidylinositol anchor attachment 1
10026  PIGK; phosphatidylinositol glycan anchor biosynthesis class K
94005  PIGS; phosphatidylinositol glycan anchor biosynthesis class S
51604  PIGT; phosphatidylinositol glycan anchor biosynthesis class T
128869  PIGU; phosphatidylinositol glycan anchor biosynthesis class U
Metabolite
C01194  1-Phosphatidyl-D-myo-inositol
G10610  UDP-N-acetyl-D-glucosamine
G13150   
Reference
PMID:32156170
  Authors
Kinoshita T.
  Title
Biosynthesis and biology of mammalian GPI-anchored proteins.
  Journal
Open Biol 10:190290 (2020)
DOI:10.1098/rsob.190290
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