| Entry |
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| Symbol |
PIGT, CGI-06, MCAHS3, NDAP, PIG-T, PNH2
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| Name |
(RefSeq) phosphatidylinositol glycan anchor biosynthesis class T
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| KO |
| K05292 | GPI-anchor transamidase subunit T |
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| Organism |
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| Pathway |
| hsa00563 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
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| Network |
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| Element |
| N00748 | GPI-anchor biosynthesis |
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| Disease |
| H01053 | Paroxysmal nocturnal hemoglobinuria |
| H01486 | Multiple congenital anomalies-hypotonia-seizures syndrome |
| H01489 | Inherited glycosylphosphatidylinositol deficiencies |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
51604 (PIGT)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
20:45416141..45426241
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| AA seq |
578 aa
MAAAMPLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQR
EGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTV
TDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREV
VCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQ
TLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPP
TTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSG
YGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQ
DRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA
AKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCY
GSFYNLLTRTFHIEEPRTGGLAKRLANLIRRARGVPPL |
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| NT seq |
1737 nt +upstreamnt +downstreamnt
atggcggcggctatgccgcttgctctgctcgtcctgttgctcctggggcccggcggctgg
tgccttgcagaacccccacgcgacagcctgcgggaggaacttgtcatcaccccgctgcct
tccggggacgtagccgccacattccagttccgcacgcgctgggattcggagcttcagcgg
gaaggagtgtcccattacaggctctttcccaaagccctggggcagctgatctccaagtat
tctctacgggagctgcacctgtcattcacacaaggcttttggaggacccgatactggggg
ccacccttcctgcaggccccatcaggtgcagagctgtgggtctggttccaagacactgtc
actgatgtggataaatcttggaaggagctcagtaatgtcctctcagggatcttctgcgcc
tctctcaacttcatcgactccaccaacacagtcactcccactgcctccttcaaacccctg
ggtctggccaatgacactgaccactactttctgcgctatgctgtgctgccgcgggaggtg
gtctgcaccgaaaacctcaccccctggaagaagctcttgccctgtagttccaaggcaggc
ctctctgtgctgctgaaggcagatcgcttgttccacaccagctaccactcccaggcagtg
catatccgccctgtttgcagaaatgcacgctgtactagcatctcctgggagctgaggcag
accctgtcagttgtatttgatgccttcatcacggggcagggaaagaaagactggtccctc
ttccggatgttctcccgaaccctcacggagccctgccccctggcttcagagagccgagtc
tatgtggacatcaccacctacaaccaggacaacgagacattagaggtgcacccacccccg
accactacatatcaggacgtcatcctaggcactcggaagacctatgccatctatgacttg
cttgacaccgccatgatcaacaactctcgaaacctcaacatccagctcaagtggaagaga
cccccagagaatgaggcccccccagtgcccttcctgcatgcccagcggtacgtgagtggc
tatgggctgcagaagggggagctgagcacactgctgtacaacacccacccataccgggcc
ttcccggtgctgctgctggacaccgtaccctggtatctgcggctgtatgtgcacaccctc
accatcacctccaagggcaaggagaacaaaccaagttacatccactaccagcctgcccag
gaccggctgcaaccccacctcctggagatgctgattcagctgccggccaactcagtcacc
aaggtttccatccagtttgagcgggcgctgctgaagtggaccgagtacacgccagatcct
aaccatggcttctatgtcagcccatctgtcctcagcgcccttgtgcccagcatggtagca
gccaagccagtggactgggaagagagtcccctcttcaacagcctgttcccagtctctgat
ggctctaactactttgtgcggctctacacggagccgctgctggtgaacctgccgacaccg
gacttcagcatgccctacaacgtgatctgcctcacgtgcactgtggtggccgtgtgctat
ggctccttctacaatctcctcacccgaaccttccacatcgaggagccccgcacaggtggc
ctggccaagcggctggccaaccttatccggcgcgcccgaggtgtccccccactctga |
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