| Entry |
|
| Name |
Yersinia YopP/J to TLR2/4-MAPK signaling pathway
|
| Definition |
YopP/J -| (MEK,MKK3/6,MKK4/7) |
| Expanded |
K08598 -| (5604,5605,5606,5608,6416,5609) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
|
| Gene |
| 5604 | MAP2K1; mitogen-activated protein kinase kinase 1 |
| 5605 | MAP2K2; mitogen-activated protein kinase kinase 2 |
| 5606 | MAP2K3; mitogen-activated protein kinase kinase 3 |
| 5608 | MAP2K6; mitogen-activated protein kinase kinase 6 |
| 6416 | MAP2K4; mitogen-activated protein kinase kinase 4 |
| 5609 | MAP2K7; mitogen-activated protein kinase kinase 7 |
|
| Perturbant |
| K08598 (YopP/J) | yopJ; YopJ protease family |
|
| Reference |
|
| Authors |
Rosadini CV, Zanoni I, Odendall C, Green ER, Paczosa MK, Philip NH, Brodsky IE, Mecsas J, Kagan JC |
| Title |
A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4. |
| Journal |
|
| Reference |
|
| Authors |
Mukherjee S, Keitany G, Li Y, Wang Y, Ball HL, Goldsmith EJ, Orth K |
| Title |
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. |
| Journal |
|
| Reference |
|
| Authors |
Orth K, Palmer LE, Bao ZQ, Stewart S, Rudolph AE, Bliska JB, Dixon JE |
| Title |
Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. |
| Journal |
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| LinkDB |
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