KEGG   NETWORK: N00899
Entry
N00899                      Network                                
Name
Glutathione biosynthesis
Definition
5-Oxoproline -- OPLAH -> Glu -- (GCLC+GCLM) >> GSS -> GSH -- GPX -> GSSG
  Expanded
C01879 -- 26873 -> C00025 -- (2729+2730) >> 2937 -> C00051 -- (2876,2877,2878,2879,2880,257202,2882,493869) -> C00127
Class
nt06026 Glutathione biosynthesis
Type
Reference
Pathway
hsa00480  Glutathione metabolism
Gene
26873  OPLAH; 5-oxoprolinase, ATP-hydrolysing
2729  GCLC; glutamate-cysteine ligase catalytic subunit
2730  GCLM; glutamate-cysteine ligase modifier subunit
2937  GSS; glutathione synthetase
2876  GPX1; glutathione peroxidase 1
2877  GPX2; glutathione peroxidase 2
2878  GPX3; glutathione peroxidase 3
2879  GPX4; glutathione peroxidase 4
2880  GPX5; glutathione peroxidase 5
257202  GPX6; glutathione peroxidase 6
2882  GPX7; glutathione peroxidase 7
493869  GPX8; glutathione peroxidase 8 (putative)
Metabolite
C01879  5-Oxoproline
C00025  L-Glutamate
C00051  Glutathione
C00127  Glutathione disulfide
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