Homo sapiens (human): 26873 Help Entry 26873             CDS       T01001                                  Symbol OPLAH, 5-Opase, OPLA, OPLAHD Name (RefSeq) 5-oxoprolinase, ATP-hydrolysing   KO K01469   5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways Network nt06026  Glutathione biosynthesis   Element N00899   5-Oxoproline metabolism Disease H02313   5-Oxoprolinase deficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     26873 (OPLAH) Enzymes [BR:hsa01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.2  In cyclic amides     3.5.2.9  5-oxoprolinase (ATP-hydrolysing)      26873 (OPLAH) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hydantoinase_B Hydantoinase_A Hydant_A_N Hydant_A_C Motif Other DBs NCBI-GeneID:  26873 NCBI-ProteinID:  NP_060040 OMIM:  614243 HGNC:  8149 Ensembl:  ENSG00000178814 UniProt:  O14841 LinkDB All DBs Position 8:complement(144050322..144063961) Genome browser AA seq 1288 aa AA seqDB search MGSPEGRFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYADAPTEGIRRILEQEAG MLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTRGFRDLLHIGTQARGDLFD LAVPMPEVLYEEVLEVDERVVLHRGEAGTGTPVKGRTGDLLEVQQPVDLGALRGKLEGLL SRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSLSSEAMPMVRIVPRGHTACADAY LTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAPMDTFSGSSAVLSGPAGGVVGYSAT TYQQEGGQPVIGFDMGGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRL FFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGENQPLSP EASRKALEAVATEVNSFLTNGPCPASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLLYA PETFVQLDQRLSRLEEQCVDALQAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATA RSPRAGDFGAAFVERYMREFGFVIPERPVVVDDVRVRGTGRSGLRLEDAPKAQTGPPRVD KMTQCYFEGGYQETPVYLLAELGYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICIS VGAEVPGTVGPQLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDG GLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFW PGQTRPVFYVASRGHHADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEA LRAPGKVPNCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANA ELAVRDMLRAFGTSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEV FGNLNAPRAVTLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNV LTSQRVVDVILGAFGACAASQGCMNNVTLGNAHMGYYETVAGGAGAGPSWHGRSGVHSHM TNTRITDPEILESRYPVILRRFELRRGSGGRGRFRGGDGVTRELLFREEALLSVLTERRA FRPYGLHGGEPGARGLNLLIRKNGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDPA PPPGSPPQALAFPEHGSVYEYRRAQEAV NT seq 3867 nt NT seq  +upstreamnt  +downstreamnt atgggcagccccgagggccgcttccactttgccatcgaccgtgggggtaccttcacagac gtctttgcccagtgcccaggggggcacgtgcgggtcttaaaactgctctcagaggaccct gccaactatgcggacgcgccaaccgaaggcatccgccgcatcctggagcaggaggccggc atgctcctgccccgggaccagccgctggactccagtcatatcgccagcatccgcatgggc accacagtggccaccaacgcactgctggagcggaagggggagcgggtggcgctgctggtg acacgtggcttccgagacctgctgcacattggcacccaagcccgtggggacctctttgac ctggccgtgcccatgcctgaggtgctgtatgaagaggtgctggaggtggacgaacgcgtg gtgctgcaccgtggagaggcgggcaccgggacgcctgtgaaaggccgcacgggggacctg ctggaagtgcagcagcctgtggacctgggggccctgcgtgggaagctggaggggctgcta tctcgaggcatccgcagcctggctgtggtgctcatgcactcgtacacgtgggcccagcat gagcagcaggtgggtgtgctggcccgggagctgggcttcacgcacgtgtcactgtcctcg gaggccatgcccatggtgcgcatcgtccctcgggggcacacggcctgtgccgacgcctac ctcacgcccgccatccagcgctacgtgcagggcttctgccgtggcttccagggccaactc aaggatgtgcaggtgttgttcatgcgctccgatggcggcctggcgcccatggacaccttc agcggctccagtgctgtgctctcgggcccggccggcggcgtggtgggctactcagccacc acctaccagcaggagggtggccagcctgtcatcggctttgacatgggaggcacgtccacg gatgtgagccgctatgctggggaattcgagcacgtcttcgaggccagcacagctggcgtc accctccaggccccgcagctggacatcaacaccgtggcagcgggagggggttcccgcctc ttcttcaggtctggcctctttgtggttgggcccgagtcagcaggagcccacccaggaccc gcctgctaccgcaaagggggccctgtgacagtgacggatgctaatctggtcctgggtcgc ctgctgcctgcctccttcccctgcatttttgggccgggagagaaccaaccactttcccct gaggcctcccgcaaagccctggaggctgtggccactgaggtcaacagcttcctgaccaac gggccctgcccggcctccccgctgagcctggaggaggtggccatggggttcgtgcgcgtg gccaacgaggccatgtgccggcccatccgtgcactcacgcaggcaagaggccatgacccc tcagcccatgtgctggcctgctttgggggagctggtgggcagcatgcatgtgccatcgcc cgggccctgggcatggacacggtgcacatccacaggcacagtgggctgctgtcggccctg gggctggccctggctgacgtggtgcatgaggcacaggaaccctgctccctgctctacgcg cctgagaccttcgtgcagctggaccagaggctgagccgcctggaggagcagtgtgtggat gctctgcaggcccagggcttccccaggtcccagatcagcactgagagcttcctgcacctg cgctaccagggcacggactgtgctctgatggtgtctgcccaccagcacccagccacagcc cgctcgccccgtgcgggggacttcggggcagcctttgtggagcggtacatgagggagttt ggctttgtcatacctgagcggccggtggtcgtggacgatgtgcgagtgcggggcaccggc cgcagtggtcttcgcctcgaggatgcccccaaagcccagaccgggcctccccgggtggac aagatgacccagtgctactttgaggggggctaccaggagacccctgtgtacctgctggca gagctgggctatgggcacaagctccatgggccctgcctcatcatcgacagtaacagcacc atcctggtggagccaggttgccaggcagaggtgaccaagacaggggacatctgcatctcc gtgggggccgaagtccccggcacagtgggcccccagctggaccctatccagctgtccatc ttctcacaccgcttcatgagcattgctgagcagatgggccgcatcctgcagcgcacagcc atctccaccaacatcaaggagcgtctggacttctcctgtgccctctttgggcccgatggg gggctggtgtccaatgccccccacatccctgtgcacctgggtgccatgcaggagacggtg cagttccagattcagcacctgggggccgatctccaccctggcgacgtgctactgagcaac catcccagtgccgggggcagccacctgccagacctgactgttatcacaccggtgttttgg ccgggtcagacgcggcctgtgttctatgtggccagccgagggcaccacgcagacatcggg ggcatcacaccaggctccatgcccccccactccaccatgctgcaacaggagggtgccgtc tttctgtccttcaaacttgtccaggggggcgtcttccaggaggaggcggtgacggaggcc ctgcgggcgccaggcaaggtccccaactgcagcggaaccagaaacctgcacgacaacctg tcggacctccgtgcccaggtggcagccaaccagaagggcatccagctggtgggggagctc attgggcagtacggcctggacgtggtgcaggcctacatgggccatattcaggcaaacgct gagctggccgtgcgagacatgttgcgtgcctttggaacctcccggcaggcccggggcctg cccctggaggtgtcctcggaagaccacatggacgacggttcccccatccgcctccgtgtg cagatcagcctgagtcagggcagcgccgtgtttgacttcagcggcactgggccggaggtg tttggtaatctcaacgcaccgcgggccgtaaccctgtccgccctcatctactgcctgcgc tgtctggtgggccgcgacatcccactcaaccagggctgcctggcgccagtgcgcgtggtc attccccgaggctccatcctggacccgtcgcccgaggcggcggtggtgggcggcaacgtg ctcacgtcgcagcgcgtggtggatgtcatcctgggggcctttggggcctgcgccgcctcc cagggctgcatgaacaacgtgaccctgggcaacgcccacatgggctactacgagacggtg gcgggcggcgcgggcgcgggtcccagctggcacgggcgcagcggtgtgcacagccacatg accaacacacgcatcaccgaccctgagatcctggagagccggtacccggtcatcctgcgc cgcttcgagctgcggcggggctcggggggcagaggccgcttccgaggcggcgacggcgtc acccgcgagctgctctttcgtgaggaggcgctgctgtcagtgctgaccgagcgccgcgcc ttccggccatacgggctccacgggggcgagcctggcgcccgcggcctaaacctgctgatc cgcaaaaacggccggacggtgaatctgggcggcaagacgtcggtgaccgtgtaccccggg gatgtgttctgtctccacacgcccggcggcggtggctatggggacccggaggaccccgcc ccaccgccggggtcgcccccgcaagcactggcctttcccgagcacggcagcgtctatgag tatcgccgggcccaggaggccgtgtga

DBGET integrated database retrieval system