| Entry |
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| Name |
Escherichia NleB to TNF-NFKB signaling pathway
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| Definition |
NleB -| GAPDH -> (RIPK1+TRAF2) |
|---|
| Expanded |
K23657 -| 2597 -> (8737+7186) |
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| Class |
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| Type |
Pathogen
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|---|
| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
|
|---|
| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
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|---|
| Gene |
| 2597 | GAPDH; glyceraldehyde-3-phosphate dehydrogenase |
| 8737 | RIPK1; receptor interacting serine/threonine kinase 1 |
| 7186 | TRAF2; TNF receptor associated factor 2 |
|
|---|
| Perturbant |
| K23657 (NleB) | nleB; T3SS secreted effector NleB |
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|---|
| Reference |
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| Authors |
Gao X, Wang X, Pham TH, Feuerbacher LA, Lubos ML, Huang M, Olsen R, Mushegian A, Slawson C, Hardwidge PR |
|---|
| Title |
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-kappaB activation. |
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| Journal |
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| LinkDB |
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