NETWORK: N00932
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Entry
N00932 Network
Name
Escherichia NleH1 to TNF-NFKB signaling pathway
Definition
NleH1 -| RPS3 -> NFKB
Expanded
K16042 -| 6188 -> (4790+5970)
Class
nt06516
TNF signaling
nt06180
Pathogenic Escherichia coli
Type
Pathogen
Pathway
hsa05130
Pathogenic Escherichia coli infection
Disease
H00277
Enterohemorrhagic Escherichia coli (EHEC) infection
H00278
Enteropathogenic Escherichia coli (EPEC) infection
Gene
6188
RPS3; ribosomal protein S3
4790
NFKB1; nuclear factor kappa B subunit 1
5970
RELA; RELA proto-oncogene, NF-kB subunit
Perturbant
K16042
(NleH1)
nleH; non-LEE-encoded effector NleH
Reference
PMID:
20041225
Authors
Gao X, Wan F, Mateo K, Callegari E, Wang D, Deng W, Puente J, Li F, Chaussee MS, Finlay BB, Lenardo MJ, Hardwidge PR
Title
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function.
Journal
PLoS Pathog 5:e1000708 (2009)
DOI:
10.1371/journal.ppat.1000708
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