| Entry |
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| Name |
Escherichia NleF to non-canonical inflammasome signaling pathway
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| Definition |
NleF -| CASP4 |
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| Expanded |
K23658 -| 837 |
|---|
| Class |
nt06139 NLR signaling (viruses and bacteria)
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| Type |
Pathogen
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| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
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| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
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| Gene |
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| Perturbant |
| K23658 (NleF) | nleF; T3SS secreted effector NleF |
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| Reference |
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| Authors |
Song T, Li K, Zhou W, Zhou J, Jin Y, Dai H, Xu T, Hu M, Ren H, Yue J, Liang L |
|---|
| Title |
A Type III Effector NleF from EHEC Inhibits Epithelial Inflammatory Cell Death by Targeting Caspase-4. |
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| Journal |
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| Reference |
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| Authors |
Pallett MA, Crepin VF, Serafini N, Habibzay M, Kotik O, Sanchez-Garrido J, Di Santo JP, Shenoy AR, Berger CN, Frankel G |
|---|
| Title |
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells. |
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| Journal |
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| LinkDB |
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