KEGG   NETWORK: N00935
Entry
N00935                      Network                                
Name
Escherichia NleF to non-canonical inflammasome signaling pathway
Definition
NleF -| CASP4
  Expanded
K23658 -| 837
Class
nt06521 NLR signaling
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
837  CASP4; caspase 4
Perturbant
K23658 (NleF)  nleF; T3SS secreted effector NleF
Reference
  Authors
Song T, Li K, Zhou W, Zhou J, Jin Y, Dai H, Xu T, Hu M, Ren H, Yue J, Liang L
  Title
A Type III Effector NleF from EHEC Inhibits Epithelial Inflammatory Cell Death by Targeting Caspase-4.
  Journal
Biomed Res Int 2017:4101745 (2017)
DOI:10.1155/2017/4101745
Reference
  Authors
Pallett MA, Crepin VF, Serafini N, Habibzay M, Kotik O, Sanchez-Garrido J, Di Santo JP, Shenoy AR, Berger CN, Frankel G
  Title
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells.
  Journal
Mucosal Immunol 10:602-612 (2017)
DOI:10.1038/mi.2016.77
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