NETWORK: N00937
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Entry
N00937 Network
Name
Escherichia NleF to extrinsic apoptotic pathway
Definition
NleF -| CASP8
Expanded
K23658 -| 841
Class
nt06524
Apoptosis
Type
Pathogen
Pathway
hsa05130
Pathogenic Escherichia coli infection
Disease
H00277
Enterohemorrhagic Escherichia coli (EHEC) infection
H00278
Enteropathogenic Escherichia coli (EPEC) infection
Gene
841
CASP8; caspase 8
Perturbant
K23658
(NleF)
nleF; T3SS secreted effector NleF
Reference
PMID:
23516580
Authors
Blasche S, Mortl M, Steuber H, Siszler G, Nisa S, Schwarz F, Lavrik I, Gronewold TM, Maskos K, Donnenberg MS, Ullmann D, Uetz P, Kogl M
Title
The E. coli effector protein NleF is a caspase inhibitor.
Journal
PLoS One 8:e58937 (2013)
DOI:
10.1371/journal.pone.0058937
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