NETWORK: N00937
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Entry
N00937 Network
Name
Escherichia NleF to extrinsic apoptotic pathway
Definition
NleF -| CASP8
Expanded
K23658 -| 841
Class
nt06131
Apoptosis (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130
Pathogenic Escherichia coli infection
Disease
H00277
Enterohemorrhagic Escherichia coli (EHEC) infection
H00278
Enteropathogenic Escherichia coli (EPEC) infection
Gene
841
CASP8; caspase 8
Perturbant
K23658
(NleF)
nleF; T3SS secreted effector NleF
Reference
PMID:
23516580
Authors
Blasche S, Mortl M, Steuber H, Siszler G, Nisa S, Schwarz F, Lavrik I, Gronewold TM, Maskos K, Donnenberg MS, Ullmann D, Uetz P, Kogl M
Title
The E. coli effector protein NleF is a caspase inhibitor.
Journal
PLoS One 8:e58937 (2013)
DOI:
10.1371/journal.pone.0058937
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