| Entry |
|
| Name |
Escherichia NleH to intrinsic apoptotic pathway
|
| Definition |
NleH -> TMBIM6 -| BAX |
| Expanded |
K16042 -> 7009 -| 581 |
| Class |
|
| Type |
Pathogen
|
| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
|
| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
|
| Gene |
| 7009 | TMBIM6; transmembrane BAX inhibitor motif containing 6 |
| 581 | BAX; BCL2 associated X, apoptosis regulator |
|
| Perturbant |
| K16042 (NleH) | nleH; non-LEE-encoded effector NleH |
|
| Reference |
|
| Authors |
Hemrajani C, Berger CN, Robinson KS, Marches O, Mousnier A, Frankel G |
| Title |
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. |
| Journal |
|
| Reference |
|
| Authors |
Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, Sasakawa C |
| Title |
Cell death and infection: a double-edged sword for host and pathogen survival. |
| Journal |
|
| LinkDB |
|