KEGG   NETWORK: N00970
Entry
N00970                      Network                                
Name
Transport of calcium
Definition
Glutamate -> NMDAR -> Ca2+
  Expanded
C00025 -> (2902+(2903,2904,2905,2906)) -> C00076
Class
nt06460 Alzheimer disease
nt06461 Huntington disease
nt06462 Spinocerebellar ataxia
nt06465 Prion disease
nt06466 Pathways of neurodegeneration
Type
Reference
Pathway
hsa04724  Glutamatergic synapse
Gene
2902  GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903  GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904  GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905  GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906  GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
Metabolite
C00025  L-Glutamate
C00076  Calcium cation
Reference
PMID:12399578
  Authors
Sheng M, Kim MJ
  Title
Postsynaptic signaling and plasticity mechanisms.
  Journal
Science 298:776-80 (2002)
DOI:10.1126/science.1075333
Reference
PMID:21204408
  Authors
Blanke ML, VanDongen AMJ
  Title
Activation Mechanisms of the NMDA Receptor
  Journal
Biology of the NMDA Receptor (2009)
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