KEGG   NETWORK: N00970
Entry
N00970                      Network                                
Name
Transport of calcium
Definition
Glutamate -> NMDAR -> Ca2+
  Expanded
C00025 -> (2902+(2903,2904,2905,2906,116443,116444)) -> C00076
Class
nt06544 Neuroactive ligand signaling
nt06460 Alzheimer disease
nt06461 Huntington disease
nt06462 Spinocerebellar ataxia
nt06465 Prion disease
nt06466 Pathways of neurodegeneration
Type
Reference
Pathway
hsa04724  Glutamatergic synapse
hsa04082  Neuroactive ligand signaling
Gene
2902  GRIN1; glutamate ionotropic receptor NMDA type subunit 1
2903  GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
2904  GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
2905  GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
2906  GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
116443  GRIN3A; glutamate ionotropic receptor NMDA type subunit 3A
116444  GRIN3B; glutamate ionotropic receptor NMDA type subunit 3B
Metabolite
C00025  L-Glutamate
C00076  Calcium cation
Reference
PMID:12399578
  Authors
Sheng M, Kim MJ
  Title
Postsynaptic signaling and plasticity mechanisms.
  Journal
Science 298:776-80 (2002)
DOI:10.1126/science.1075333
Reference
PMID:21204408
  Authors
Blanke ML, VanDongen AMJ
  Title
Activation Mechanisms of the NMDA Receptor
  Journal
Biology of the NMDA Receptor (2009)
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