| Entry |
|
|---|
| Name |
PERK-ATF4 signaling pathway
|
|---|
| Definition |
EIF2AK3 -> EIF2S1 -> ATF4 => DDIT3 |
|---|
| Expanded |
9451 -> 1965 -> 468 => 1649 |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
| hsa04141 | Protein processing in endoplasmic reticulum |
|
|---|
| Gene |
| 9451 | EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3 |
| 1965 | EIF2S1; eukaryotic translation initiation factor 2 subunit alpha |
| 468 | ATF4; activating transcription factor 4 |
| 1649 | DDIT3; DNA damage inducible transcript 3 |
|
|---|
| Reference |
|
|---|
| Authors |
Walter P, Ron D |
|---|
| Title |
The unfolded protein response: from stress pathway to homeostatic regulation. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Kim I, Xu W, Reed JC |
|---|
| Title |
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Deldicque L |
|---|
| Title |
Endoplasmic reticulum stress in human skeletal muscle: any contribution to sarcopenia? |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Basseri S, Austin RC |
|---|
| Title |
Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. |
|---|
| Journal |
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|---|
| LinkDB |
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